Douglas A. Lauffenburger

Orcid: 0000-0002-0050-989X

According to our database1, Douglas A. Lauffenburger authored at least 23 papers between 1994 and 2019.

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Bibliography

2019
Computational translation of genomic responses from experimental model systems to humans.
PLoS Comput. Biol., 2019

2018
Exploiting glycan topography for computational design of Env glycoprotein antigenicity.
PLoS Comput. Biol., 2018

2013
Linking Proteomic and Transcriptional Data through the Interactome and Epigenome Reveals a Map of Oncogene-induced Signaling.
PLoS Comput. Biol., 2013

Identification of signaling pathways related to drug efficacy in hepatocellular carcinoma via integration of phosphoproteomic, genomic and clinical data.
Proceedings of the 13th IEEE International Conference on BioInformatics and BioEngineering, 2013

2012
Modular Design of Artificial Tissue Homeostasis: Robust Control through Synthetic Cellular Heterogeneity.
PLoS Comput. Biol., 2012

CellNOptR: a flexible toolkit to train protein signaling networks to data using multiple logic formalisms.
BMC Syst. Biol., 2012

Creating and analyzing pathway and protein interaction compendia for modelling signal transduction networks.
BMC Syst. Biol., 2012

2011
MCAM: Multiple Clustering Analysis Methodology for Deriving Hypotheses and Insights from High-Throughput Proteomic Datasets.
PLoS Comput. Biol., 2011

Training Signaling Pathway Maps to Biochemical Data with Constrained Fuzzy Logic: Quantitative Analysis of Liver Cell Responses to Inflammatory Stimuli.
PLoS Comput. Biol., 2011

A Dynamical Systems Model for Combinatorial Cancer Therapy Enhances Oncolytic Adenovirus Efficacy by MEK-Inhibition.
PLoS Comput. Biol., 2011

2009
Fuzzy Logic Analysis of Kinase Pathway Crosstalk in TNF/EGF/Insulin-Induced Signaling.
PLoS Comput. Biol., 2009

Learning Signaling Network Structures with Sparsely Distributed Data.
J. Comput. Biol., 2009

Transforming Boolean models to continuous models: methodology and application to T-cell receptor signaling.
BMC Syst. Biol., 2009

2008
Flexible informatics for linking experimental data to mathematical models via <i>DataRail</i>.
Bioinform., 2008

Modeling pro-death signaling pathways in cancer hepatocytes using multi-combinatorial treatments of inhibitors and stimuli.
Proceedings of the 8th IEEE International Conference on Bioinformatics and Bioengineering, 2008

2007
Modeling HER2 Effects on Cell Behavior from Mass Spectrometry Phosphotyrosine Data.
PLoS Comput. Biol., 2007

Decision tree modeling predicts effects of inhibiting contractility signaling on cell motility.
BMC Syst. Biol., 2007

2005
Bayesian analysis of signaling networks governing embryonic stem cell fate decisions.
Bioinform., 2005

Modeling of signal-response cascades using decision tree analysis.
Bioinform., 2005

2004
Cue-Signal-Response Analysis of TNF-Induced Apoptosis by Partial Least Squares Regression of Dynamic Multivariate Data.
J. Comput. Biol., 2004

Analysis of Signaling Pathways in Human T-Cells Using Bayesian Network Modeling of Single Cell Data.
Proceedings of the 3rd International IEEE Computer Society Computational Systems Bioinformatics Conference, 2004

2003
Modeling cellular signal processing using interacting Markov chains.
Proceedings of the 2003 IEEE International Conference on Acoustics, 2003

1994
Probability of Autocrine Ligand Capture by Cell-Surface Receptors: Implications for Ligand Secretion Measurements.
J. Comput. Biol., 1994


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