Yun Tang

Orcid: 0000-0003-2340-1109

Affiliations:
  • East China University of Science and Technology, School of Pharmacy, Shanghai, China


According to our database1, Yun Tang authored at least 55 papers between 2010 and 2024.

Collaborative distances:
  • Dijkstra number2 of five.
  • Erdős number3 of four.

Timeline

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Bibliography

2024
DBPP-Predictor: a novel strategy for prediction of chemical drug-likeness based on property profiles.
J. Cheminformatics, December, 2024

Network-Based Methods and Their Applications in Drug Discovery.
J. Chem. Inf. Model., January, 2024

mtADENet: A novel interpretable method integrating multiple types of network-based inference approaches for prediction of adverse drug events.
Comput. Biol. Medicine, January, 2024

XGraphCDS: An explainable deep learning model for predicting drug sensitivity from gene pathways and chemical structures.
Comput. Biol. Medicine, January, 2024

Unraveling the Ligand-Binding Sites of CYP3A4 by Molecular Dynamics Simulations with Solvent Probes.
J. Chem. Inf. Model., 2024

MedChatZH: A tuning LLM for traditional Chinese medicine consultations.
Comput. Biol. Medicine, 2024

MetaPredictor: <i>in silico</i> prediction of drug metabolites based on deep language models with prompt engineering.
Briefings Bioinform., 2024

Herb-CMap: a multimodal fusion framework for deciphering the mechanisms of action in traditional Chinese medicine using Suhuang antitussive capsule as a case study.
Briefings Bioinform., 2024

2023
Chemical rules for optimization of chemical mutagenicity via matched molecular pairs analysis and machine learning methods.
J. Cheminformatics, December, 2023

Pharmaceutical Cocrystal Discovery via 3D-SMINBR: A New Network Recommendation Tool Augmented by 3D Molecular Conformations.
J. Chem. Inf. Model., July, 2023

Prediction of Sites of Metabolism of CYP3A4 Substrates Utilizing Docking-Derived Geometric Features.
J. Chem. Inf. Model., July, 2023

Investigation of Anti-Alzheimer's Mechanisms of Sarsasapogenin Derivatives by Network-Based Combining Structure-Based Methods.
J. Chem. Inf. Model., May, 2023

ACP-MLC: A two-level prediction engine for identification of anticancer peptides and multi-label classification of their functional types.
Comput. Biol. Medicine, May, 2023

Identification of vital chemical information via visualization of graph neural networks.
Briefings Bioinform., January, 2023

2022
Mechanistic Studies on the Stereoselectivity of FFAR1 Modulators.
J. Chem. Inf. Model., 2022

IDL-PPBopt: A Strategy for Prediction and Optimization of Human Plasma Protein Binding of Compounds via an Interpretable Deep Learning Method.
J. Chem. Inf. Model., 2022

Discovery of New Estrogen-Related Receptor α Agonists via a Combination Strategy Based on Shape Screening and Ensemble Docking.
J. Chem. Inf. Model., 2022

A multitask GNN-based interpretable model for discovery of selective JAK inhibitors.
J. Cheminformatics, 2022

In silico prediction of UGT-mediated metabolism in drug-like molecules via graph neural network.
J. Cheminformatics, 2022

ADENet: a novel network-based inference method for prediction of drug adverse events.
Briefings Bioinform., 2022

Profiling prediction of nuclear receptor modulators with multi-task deep learning methods: toward the virtual screening.
Briefings Bioinform., 2022

2021
SMINBR: An Integrated Network and Chemoinformatics Tool Specialized for Prediction of Two-Component Crystal Formation.
J. Chem. Inf. Model., 2021

Discovery of Natural Products Targeting NQO1 via an Approach Combining Network-Based Inference and Identification of Privileged Substructures.
J. Chem. Inf. Model., 2021

Pathway-Based Drug Repurposing with DPNetinfer: A Method to Predict Drug-Pathway Associations via Network-Based Approaches.
J. Chem. Inf. Model., 2021

Homotropic Cooperativity of Midazolam Metabolism by Cytochrome P450 3A4: Insight from Computational Studies.
J. Chem. Inf. Model., 2021

MetaADEDB 2.0: a comprehensive database on adverse drug events.
Bioinform., 2021

Drug repositioning by prediction of drug's anatomical therapeutic chemical code via network-based inference approaches.
Briefings Bioinform., 2021

2020
NetInfer: A Web Server for Prediction of Targets and Therapeutic and Adverse Effects via Network-Based Inference Methods.
J. Chem. Inf. Model., 2020

Computational Insights into Molecular Activation and Positive Cooperative Mechanisms of FFAR1 Modulators.
J. Chem. Inf. Model., 2020

Dissecting the Structural Plasticity and Dynamics of Cytochrome P450 2B4 by Molecular Dynamics Simulations.
J. Chem. Inf. Model., 2020

Computational Insight into the Allosteric Activation Mechanism of Farnesoid X Receptor.
J. Chem. Inf. Model., 2020

2019
Insights into the antineoplastic mechanism of Chelidonium majus via systems pharmacology approach.
Quant. Biol., 2019

Predicting Meridian in Chinese traditional medicine using machine learning approaches.
PLoS Comput. Biol., 2019

In Silico Prediction of Endocrine Disrupting Chemicals Using Single-Label and Multilabel Models.
J. Chem. Inf. Model., 2019

Correction to "admetSAR: A Comprehensive Source and Free Tool for Assessment of Chemical ADMET Properties".
J. Chem. Inf. Model., 2019

Computational Prediction of Site of Metabolism for UGT-Catalyzed Reactions.
J. Chem. Inf. Model., 2019

admetSAR 2.0: web-service for prediction and optimization of chemical ADMET properties.
Bioinform., 2019

2018
ADMETopt: A Web Server for ADMET Optimization in Drug Design via Scaffold Hopping.
J. Chem. Inf. Model., 2018

Multiclassification Prediction of Enzymatic Reactions for Oxidoreductases and Hydrolases Using Reaction Fingerprints and Machine Learning Methods.
J. Chem. Inf. Model., 2018

2017
Quantitative and Systems Pharmacology. 1. <i>In Silico</i> Prediction of Drug-Target Interactions of Natural Products Enables New Targeted Cancer Therapy.
J. Chem. Inf. Model., November, 2017

Computational Investigation of Ligand Binding to the Peripheral Site in CYP3A4: Conformational Dynamics and Inhibitor Discovery.
J. Chem. Inf. Model., 2017

SDTNBI: an integrated network and chemoinformatics tool for systematic prediction of drug-target interactions and drug repositioning.
Briefings Bioinform., 2017

2014
<i>In Silico</i> Prediction of Chemical Acute Oral Toxicity Using Multi-Classification Methods.
J. Chem. Inf. Model., 2014

2013
Adverse Drug Events: Database Construction and in Silico Prediction.
J. Chem. Inf. Model., 2013

Prediction of Polypharmacological Profiles of Drugs by the Integration of Chemical, Side Effect, and Therapeutic Space.
J. Chem. Inf. Model., 2013

2012
Prediction of Drug-Target Interactions and Drug Repositioning via Network-Based Inference.
PLoS Comput. Biol., 2012

In silico Prediction of Chemical Ames Mutagenicity.
J. Chem. Inf. Model., 2012

Unbinding Pathways of GW4064 from Human Farnesoid X Receptor As Revealed by Molecular Dynamics Simulations.
J. Chem. Inf. Model., 2012

Performance Evaluation of 2D Fingerprint and 3D Shape Similarity Methods in Virtual Screening.
J. Chem. Inf. Model., 2012

admetSAR: A Comprehensive Source and Free Tool for Assessment of Chemical ADMET Properties.
J. Chem. Inf. Model., 2012

In Silico Assessment of Chemical Biodegradability.
J. Chem. Inf. Model., 2012

2011
Insights into Molecular Basis of Cytochrome P450 Inhibitory Promiscuity of Compounds.
J. Chem. Inf. Model., 2011

Classification of Cytochrome P450 Inhibitors and Noninhibitors Using Combined Classifiers.
J. Chem. Inf. Model., 2011

2010
Estimation of ADME Properties with Substructure Pattern Recognition.
J. Chem. Inf. Model., 2010

Accuracy Assessment of Protein-Based Docking Programs against RNA Targets.
J. Chem. Inf. Model., 2010


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