Timothy Clark

Orcid: 0000-0001-7931-4659

According to our database1, Timothy Clark authored at least 43 papers between 1990 and 2024.

Collaborative distances:
  • Dijkstra number2 of five.
  • Erdős number3 of four.

Timeline

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Bibliography

2024
Extended Metadynamics Protocol for Binding/Unbinding Free Energies of Peptide Ligands to Class A G-Protein-Coupled Receptors.
J. Chem. Inf. Model., January, 2024

Determinants of Neutral Antagonism and Inverse Agonism in the β<sub>2</sub>-Adrenergic Receptor.
J. Chem. Inf. Model., 2024

2023
Activation/Deactivation Free-Energy Profiles for the β<sub>2</sub>-Adrenergic Receptor: Ligand Modes of Action.
J. Chem. Inf. Model., October, 2023

General Metadynamics Protocol To Simulate Activation/Deactivation of Class A GPCRs: Proof of Principle for the Serotonin Receptor.
J. Chem. Inf. Model., May, 2023

2019
Propagation of Holes and Electrons in Metal-Organic Frameworks.
J. Chem. Inf. Model., 2019

Universal Activation Index for Class A GPCRs.
J. Chem. Inf. Model., 2019

2018
Methods and Tools to Enhance Rigor and Reproducibility of Biomedical Research.
Proceedings of the AMIA 2018, 2018

2017
The hpCADD NDDO Hamiltonian: Parametrization.
J. Chem. Inf. Model., August, 2017

An Efficient Metadynamics-Based Protocol To Model the Binding Affinity and the Transition State Ensemble of G-Protein-Coupled Receptor Ligands.
J. Chem. Inf. Model., 2017

Conformation and Dynamics of Human Urotensin II and Urotensin Related Peptide in Aqueous Solution.
J. Chem. Inf. Model., 2017

Big Data to Knowledge (BD2K) and the Application of Metadata.
Proceedings of the AMIA 2017, 2017

2016
Can Simulations and Modeling Decipher NMR Data for Conformational Equilibria? Arginine-Vasopressin.
J. Chem. Inf. Model., 2016

2014
Parameterization to NDDO-based polarizable force field.
J. Cheminformatics, 2014

Quantum-mechanics-based molecular interaction fields for 3D-QSAR.
J. Cheminformatics, 2014

2013
Economical and Accurate Protocol for Calculating Hydrogen-Bond-Acceptor Strengths.
J. Chem. Inf. Model., 2013

Quantum Mechanics-Based Properties for 3D-QSAR.
J. Chem. Inf. Model., 2013

Geospatial site suitability modeling for US department of defense humanitarian assistance projects.
Proceedings of the 10th Proceedings of the International Conference on Information Systems for Crisis Response and Management, 2013

2012
Predicting the Sites and Energies of Noncovalent Intermolecular Interactions Using Local Properties.
J. Chem. Inf. Model., 2012

3D-QSAR Based on Quantum-Chemical Molecular Fields: Toward an Improved Description of Halogen Interactions.
J. Chem. Inf. Model., 2012

2011
Conformation-Dependent QSPR Models: logP<sub>OW</sub>.
J. Chem. Inf. Model., 2011

2010
A Surface-Integral Model for Log <i>P</i><sub>OW</sub>.
J. Chem. Inf. Model., 2010

Insolubility Classification with Accurate Prediction Probabilities Using a MetaClassifier.
J. Chem. Inf. Model., 2010

Tautomers and reference 3D-structures: the orphans of <i>in silico</i> drug design.
J. Comput. Aided Mol. Des., 2010

2009
Sharpening the Toolbox of Computational Chemistry: A New Approximation of Critical <i>F</i>-Values for Multiple Linear Regression.
J. Chem. Inf. Model., 2009

2006
In Silico Prediction of Buffer Solubility Based on Quantum-Mechanical and HQSAR- and Topology-Based Descriptors.
J. Chem. Inf. Model., 2006

2005
Nanoporous Carbon Allotropes by Septupling Map Operations.
J. Chem. Inf. Model., 2005

Surface-Integral QSPR Models: Local Energy Properties.
J. Chem. Inf. Model., 2005

2004
New Molecular Descriptors Based on Local Properties at the Molecular Surface and a Boiling-Point Model Derived from Them.
J. Chem. Inf. Model., 2004

Enthalpies of formation from B3LYP calculations.
J. Comput. Chem., 2004

2003
The structure and stability of Si60 and Ge60 cages: A computational study.
J. Comput. Chem., 2003

2001
A Temperature-Dependent Quantum Mechanical/Neural Net Model for Vapor Pressure.
J. Chem. Inf. Comput. Sci., 2001

A Quantum Mechanical/Neural Net Model for Boiling Points with Error Estimation.
J. Chem. Inf. Comput. Sci., 2001

2000
QM/NN QSPR Models with Error Estimation: Vapor Pressure and LogP.
J. Chem. Inf. Comput. Sci., 2000

1998
Enhanced 3D-Databases: A Fully Electrostatic Database of AM1-Optimized Structures.
J. Chem. Inf. Comput. Sci., 1998

1997
Empirical force field and ab initio calculations on allyl cations.
J. Comput. Chem., 1997

Empirical force-field and ab initio calculations on delocalized open chain cations.
J. Comput. Chem., 1997

VESPA: A new, fast approach to electrostatic potential-derived atomic charges from semiempirical methods.
J. Comput. Chem., 1997

1996
A new method for empirical force field calculations on localized and delocalized carbocations.
J. Comput. Chem., 1996

Electronic publishing and the Web.
Proceedings of WebNet 96, 1996

1994
The Natural Atomic Orbital Point Charge Model for PM3: Multipole Moments and Molecular Electrostatic Potentials.
J. Comput. Chem., 1994

1993
Multicenter point charge model for high-quality molecular electrostatic potentials from AM1 calculations.
J. Comput. Chem., 1993

Molecular orbital studies of enzyme mechanisms. II. Catalytic oxidation of alcohols by liver alcohol dehydrogenase.
J. Comput. Chem., 1993

1990
Can we predict reactivity using MO calculations?
J. Chem. Inf. Comput. Sci., 1990


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