Thomas Lengauer
Orcid: 0000-0003-3801-2640Affiliations:
- University Hospital Cologne, Germany
- Max-Planck-Institut for Informatics, Saarbrücken, Germany (former)
According to our database1,
Thomas Lengauer
authored at least 191 papers
between 1979 and 2023.
Collaborative distances:
Collaborative distances:
Awards
ACM Fellow
ACM Fellow 2021, "For contributions to bioinformatics and medical informatics".
Timeline
Legend:
Book In proceedings Article PhD thesis Dataset OtherLinks
Online presence:
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on zbmath.org
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on orcid.org
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on id.loc.gov
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on gi.de
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on d-nb.info
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on isni.org
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on dl.acm.org
On csauthors.net:
Bibliography
2023
Incorporating temporal dynamics of mutations to enhance the prediction capability of antiretroviral therapy's outcome for HIV-1.
CoRR, 2023
2018
geno2pheno[ngs-freq]: a genotypic interpretation system for identifying viral drug resistance using next-generation sequencing data.
Nucleic Acids Res., 2018
2017
J. Graph Algorithms Appl., 2017
Selecting optimal minimum spanning trees that share a topological correspondence with phylogenetic trees.
CoRR, 2017
ISCB's initial reaction to New England Journal of Medicine editorial on data sharing.
Bioinform., 2017
2016
ISCB's Initial Reaction to <i>The New England Journal of Medicine</i> Editorial on Data Sharing.
PLoS Comput. Biol., 2016
DeepBlue epigenomic data server: programmatic data retrieval and analysis of epigenome region sets.
Nucleic Acids Res., 2016
2015
ISCB Ebola Award for Important Future Research on the Computational Biology of Ebola Virus.
PLoS Comput. Biol., 2015
Message from the ISCB: ISCB Ebola award for important future research on the computational biology of Ebola virus.
Bioinform., 2015
Database J. Biol. Databases Curation, 2015
2014
BiQ Analyzer HiMod: an interactive software tool for high-throughput locus-specific analysis of 5-methylcytosine and its oxidized derivatives.
Nucleic Acids Res., 2014
Correction to On the Applicability of Elastic Network Normal Modes in Small-Molecule Docking.
J. Chem. Inf. Model., 2014
J. Comput. Chem., 2014
2013
PLoS Comput. Biol., 2013
Analysis of Physicochemical and Structural Properties Determining HIV-1 Coreceptor Usage.
PLoS Comput. Biol., 2013
A method for finding consensus breakpoints in the cancer genome from copy number data.
Bioinform., 2013
2012
History-alignment models for bias-aware prediction of virological response to HIV combination therapy.
Proceedings of the Fifteenth International Conference on Artificial Intelligence and Statistics, 2012
J. Chem. Inf. Model., 2012
Improving HIV coreceptor usage prediction in the clinic using hints from next-generation sequencing data.
Bioinform., 2012
2011
BiQ Analyzer HT: locus-specific analysis of DNA methylation by high-throughput bisulfite sequencing.
Nucleic Acids Res., 2011
Genotypic tropism testing by massively parallel sequencing: qualitative and quantitative analysis.
BMC Medical Informatics Decis. Mak., 2011
Classification with correlated features: unreliability of feature ranking and solutions.
Bioinform., 2011
2010
Nucleic Acids Res., 2010
Improving disease gene prioritization using the semantic similarity of Gene Ontology terms.
Bioinform., 2010
Bioinform., 2010
2009
Bioinform., 2009
Proceedings of the German Conference on Bioinformatics 2009, 2009
2008
PLoS Comput. Biol., 2008
Integrative Visual Analysis of the Effects of Alternative Splicing on Protein Domain Interaction Networks.
J. Integr. Bioinform., 2008
Rtreemix: an R package for estimating evolutionary pathways and genetic progression scores.
Bioinform., 2008
Proceedings of the Proceedings 16th International Conference on Intelligent Systems for Molecular Biology (ISMB), 2008
Proceedings of the Machine Learning, 2008
Proceedings of the ECCB'08 Proceedings, 2008
Proceedings of the Ontologies and Text Mining for Life Sciences: Current Status and Future Perspectives, 24.03., 2008
Proceedings of the 6th Asia-Pacific Bioinformatics Conference, 2008
2007
Structural Descriptors of gp120 V3 Loop for the Prediction of HIV-1 Coreceptor Usage.
PLoS Comput. Biol., 2007
PLoS Comput. Biol., 2007
Moment invariants as shape recognition technique for comparing protein binding sites.
Bioinform., 2007
Functional evaluation of domain-domain interactions and human protein interaction networks.
Bioinform., 2007
2006
Flexible Docking of Ligands into Synthetic Receptors Using a Two-Sided Incremental Construction Algorithm.
J. Chem. Inf. Model., 2006
J. Chem. Inf. Model., 2006
Fully Automated Flexible Docking of Ligands into Flexible Synthetic Receptors Using Forward and Inverse Docking Strategies.
J. Chem. Inf. Model., 2006
Improving the quality of protein structure models by selecting from alignment alternatives.
BMC Bioinform., 2006
BMC Bioinform., 2006
Improved scoring of functional groups from gene expression data by decorrelating GO graph structure.
Bioinform., 2006
DynaPred: A structure and sequence based method for the prediction of MHC class I binding peptide sequences and conformations.
Proceedings of the Proceedings 14th International Conference on Intelligent Systems for Molecular Biology 2006, 2006
Arevir: A Secure Platform for Designing Personalized Antiretroviral Therapies Against HIV.
Proceedings of the Data Integration in the Life Sciences, Third International Workshop, 2006
2005
J. Chem. Inf. Model., 2005
POEM: Parameter Optimization Using Ensemble Methods: Application to Target Specific Scoring Functions.
J. Chem. Inf. Model., 2005
J. Comput. Biol., 2005
The DFG Priority Program "Informatics Methods for the Analysis and Interpretation of Large Genomic Datasets".
it Inf. Technol., 2005
BMC Bioinform., 2005
Estimating cancer survival and clinical outcome based on genetic tumor progression scores.
Bioinform., 2005
BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing.
Bioinform., 2005
Computational methods for the design of effective therapies against drug resistant HIV strains.
Bioinform., 2005
Mtreemix: a software package for learning and using mixture models of mutagenetic trees.
Bioinform., 2005
Characterization of Novel HIV Drug Resistance Mutations Using Clustering, Multidimensional Scaling and SVM-Based Feature Ranking.
Proceedings of the Knowledge Discovery in Databases: PKDD 2005, 2005
Supervised and Unsupervised Approaches for Analyzing Covariation and Phenotypic Impact of HIV Drug Resistance Mutations.
Proceedings of the Lernen, 2005
Proceedings of the ECCB/JBI'05 Proceedings, Fourth European Conference on Computational Biology/Sixth Meeting of the Spanish Bioinformatics Network (Jornadas de BioInformática), Palacio de Congresos, Madrid, Spain, September 28, 2005
2004
Arby: automatic protein structure prediction using profile-profile alignment and confidence measures.
Bioinform., 2004
The Helmholtz Network for Bioinformatics: an integrative web portal for bioinformatics resources.
Bioinform., 2004
Learning Mixtures of Localized Rules by Maximizing the Area Under the ROC Curve.
Proceedings of the ROC Analysis in Artificial Intelligence, 1st International Workshop, 2004
2003
Nucleic Acids Res., 2003
J. Parallel Distributed Comput., 2003
Disease-associated variants in PYPAF1 and NOD2 result in similar alterations of conserved sequence.
Bioinform., 2003
Bioinform., 2003
Proceedings of the Eleventh International Conference on Intelligent Systems for Molecular Biology, June 29, 2003
Analyzing resistance phenomena in HIV with bioinformatics methods.
Proceedings of the European Conference on Computational Biology (ECCB 2003), 2003
2002
Diversity and complexity of HIV-1 drug resistance: A bioinformatics approach to predicting phenotype from genotype.
Proc. Natl. Acad. Sci. USA, 2002
J. Comput. Aided Mol. Des., 2002
ProML - the Protein Markup Language for specification of protein sequences, structures and families.
Silico Biol., 2002
A hypergraph-based method for unification of existing protein structure- and sequence-families.
Silico Biol., 2002
Improving fold recognition of protein threading by experimental distance constraints.
Silico Biol., 2002
Co-clustering of biological networks and gene expression data.
Proceedings of the Tenth International Conference on Intelligent Systems for Molecular Biology, 2002
ECCB 2002 Organization.
Proceedings of the European Conference on Computational Biology (ECCB 2002), 2002
Editorial.
Proceedings of the European Conference on Computational Biology (ECCB 2002), 2002
2001
IEEE Intell. Syst., 2001
Centralization: a new method for the normalization of gene expression data.
Proceedings of the Ninth International Conference on Intelligent Systems for Molecular Biology, 2001
Confidence Measures for Fold Recognition.
Proceedings of the Computer science and biology: Proceedings of the German Conference on Bioinformatics, 2001
A new Method for Unification of Existing Protein Structure- and Sequence-Families.
Proceedings of the Computer science and biology: Proceedings of the German Conference on Bioinformatics, 2001
Identifying drug resistance-associated patterns in HIV genotypes.
Proceedings of the Computer science and biology: Proceedings of the German Conference on Bioinformatics, 2001
Proceedings of the Informatics - 10 Years Back. 10 Years Ahead., 2001
2000
J. Comput. Aided Mol. Des., 2000
Engineering support vector machine kernels that recognize translation initiation sites.
Bioinform., 2000
Bioinform., 2000
Proceedings of the Eighth International Conference on Intelligent Systems for Molecular Biology, 2000
Bioinformatics Problems Along the Process Line from Genomic Data to New Drugs.
Proceedings of the German Conference on Bioinformatics (GCB 2000), 2000
1999
Bioinform., 1999
Bioinform., 1999
Editorial. The Seventh International Conference on Intelligent Systems for Molecular Biology (ISMB'99).
Bioinform., 1999
Invited Lecture: Discrete Optimization Methods for Packing Problems in Two and Three Dimensions - With Applications in the Textile and Car Manufacturing Industries.
Proceedings of the Graph-Theoretic Concepts in Computer Science, 1999
Proceedings of the 4th Pacific Symposium on Biocomputing, 1999
Engineering Support Vector Machine Kerneis That Recognize Translation Initialion Sites.
Proceedings of the German Conference on Bioinformatics, 1999
Pathway analysis in metabolic databases via differetial metabolic display (DMD).
Proceedings of the German Conference on Bioinformatics, 1999
1998
J. Comput. Aided Mol. Des., 1998
Eur. J. Oper. Res., 1998
Random Generation of Embedded Graphs and an Extension to Dobrushin Uniqueness (Extended Abstract).
Proceedings of the Thirtieth Annual ACM Symposium on the Theory of Computing, 1998
1997
Multiple automatic base selection: Protein-ligand docking based on incremental construction without manual intervention.
J. Comput. Aided Mol. Des., 1997
J. Comput. Aided Mol. Des., 1997
Proceedings of the First Annual International Conference on Research in Computational Molecular Biology, 1997
Proceedings of the Randomization and Approximation Techniques in Computer Science, 1997
Detection of Distant Structural Similarities in a Set of Proteins Using a Fast Graph-Based Method.
Proceedings of the 5th International Conference on Intelligent Systems for Molecular Biology, 1997
Proceedings of the 11th International Parallel Processing Symposium (IPPS '97), 1997
DFG-Schwerpunkt: Informatikmethoden zur Analyse und Interpretation großer genomischer Datenmengen.
Proceedings of the Informatik '97, 1997
Algorithmen zum automatischen Zeichnen von Graphen im Rahmen des DFG-Schwerpunkts Effiziente Algorithmen für diskrete Probleme und ihre Anwendungen.
Proceedings of the Informatik '97, 1997
1996
An Algorithm for Finding Maximal Common Subtopologies in a Set of Protein Structures.
J. Comput. Biol., 1996
J. Comput. Aided Mol. Des., 1996
Informationstechnik Tech. Inform., 1996
Time-Efficient Flexible Superposition of Medium-Sized Molecules and Molecular Fragments.
Proceedings of the German Conference on Bioinformatics, 1996
Proceedings of the Algorithms, 1996
1995
A simulated annealing approach to the nesting problem in the textile manufacturing industry.
Ann. Oper. Res., 1995
Proceedings of the Third International Conference on Intelligent Systems for Molecular Biology, 1995
Proceedings of the Third International Conference on Intelligent Systems for Molecular Biology, 1995
APPlaUSE: Area and performance optimization in a unified placement and synthesis environment.
Proceedings of the 1995 IEEE/ACM International Conference on Computer-Aided Design, 1995
Proceedings of the 1995 European Design and Test Conference, 1995
1994
IEEE Trans. Comput. Aided Des. Integr. Circuits Syst., 1994
1993
IEEE Trans. Comput. Aided Des. Integr. Circuits Syst., 1993
1. Fachtagung "Informatik in den Biowissenschaften".
Künstliche Intell., 1993
J. ACM, 1993
Proceedings of the Fourth Annual ACM/SIGACT-SIAM Symposium on Discrete Algorithms, 1993
Proceedings of the Second Israel Symposium on Theory of Computing Systems, 1993
Informatik in den Naturwissenschaften.
Proceedings of the Informatik: Grundlagen - Amwendungen, 1993
Informatik in den technischen Disziplinen.
Proceedings of the Informatik: Grundlagen - Amwendungen, 1993
Proceedings of the Algorithmic Aspects of VLSI Layout, 1993
1992
The Correlation between the Complexities of the Nonhierarchical and Hierarchical Versions of Graph Problems.
J. Comput. Syst. Sci., 1992
Proceedings of the 1992 IEEE/ACM International Conference on Computer-Aided Design, 1992
Proceedings of the Data Structures and Efficient Algorithms, 1992
1991
IEEE Trans. Comput. Aided Des. Integr. Circuits Syst., 1991
Proceedings of the Algorithms and Data Structures, 1991
Proceedings of the Automata, Languages and Programming, 18th International Colloquium, 1991
Proceedings of the conference on European design automation, 1991
1990
Theor. Comput. Sci., 1990
Proceedings of the IEEE/ACM International Conference on Computer-Aided Design, 1990
VLSI Theory.
Proceedings of the Handbook of Theoretical Computer Science, 1990
Combinatorial algorithms for integrated circuit layout.
Applicable theory in computer science, Teubner, ISBN: 978-0-471-92838-6, 1990
1989
1988
SIAM J. Comput., 1988
ZOR Methods Model. Oper. Res., 1988
Efficient processing of hierarchical graphs for engineering design.
Bull. EATCS, 1988
Efficient Analysis of Graph Properties on Context-free Graph Languages (Extended Abstract).
Proceedings of the Automata, Languages and Programming, 15th International Colloquium, 1988
1987
IEEE Trans. Comput. Aided Des. Integr. Circuits Syst., 1987
Efficient Algorithms for Finding Minimum Spanning Forests of Hierarchically Defined Graphs.
J. Algorithms, 1987
1986
An analysis of ternary simulation as a tool for race detection in digital MOS circuits.
Integr., 1986
Proceedings of the Automata, Languages and Programming, 13th International Colloquium, 1986
Proceedings of the GI - 16. Jahrestagung I, Berlin, 6.-10. Oktober 1986, Proceedings, 1986
Proceedings of the VLSI Algorithms and Architectures, 1986
Proceedings of the VLSI Algorithms and Architectures, 1986
1984
Proceedings of the Fachgespräche auf der 14. GI-Jahrestagung, 1984
1983
Efficient Algorithms for the Constraint Generation for Integrated Circuit Layout Compaction.
Proceedings of the WG '83, 1983
1982
Cube-Connected Cycles - Shuffle Exchange Graph - Das aktuelle Schlagwort.
Inform. Spektrum, 1982
The Complexity of Compacting Hierarchically Specified Layouts of Integrated Circuits (Preliminary Version)
Proceedings of the 23rd Annual Symposium on Foundations of Computer Science, 1982
1981
1980
1979
ACM Trans. Program. Lang. Syst., 1979
Proceedings of the 11h Annual ACM Symposium on Theory of Computing, April 30, 1979