Stephen T. C. Wong

Orcid: 0000-0001-9188-6502

Affiliations:
  • Houston Methodist Hospital Research Institute, Department of Systems Medicine and Bioengineering, Houston, TX, USA
  • Harvard Medical School, Boston, MA, USA
  • Lehigh University, Bethlehem, PA, USA (PhD 1991)


According to our database1, Stephen T. C. Wong authored at least 237 papers between 1989 and 2024.

Collaborative distances:

Awards

IEEE Fellow

IEEE Fellow 2018, "For leadership in drug discovery, systems biology, bioinformatics, and health analytics".

Timeline

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Bibliography

2024
Detecting Wilson's disease from unstructured connected speech: An embedding-based approach augmented by attention and bi-directional dependency.
Speech Commun., January, 2024

MUSTANG: Multi-sample spatial transcriptomics data analysis with cross-sample transcriptional similarity guidance.
Patterns, 2024

2023
Artificial Intelligence-Powered Acoustic Analysis System for Dysarthria Severity Assessment.
Adv. Intell. Syst., October, 2023

BBox-Guided Segmentor: Leveraging expert knowledge for accurate stroke lesion segmentation using weakly supervised bounding box prior.
Comput. Medical Imaging Graph., 2023

Storyline-Centric Detection of Aphasia and Dysarthria in Stroke Patient Transcripts.
Proceedings of the 5th Clinical Natural Language Processing Workshop, 2023

2022
A Time-Series Feature-Based Recursive Classification Model to Optimize Treatment Strategies for Improving Outcomes and Resource Allocations of COVID-19 Patients.
IEEE J. Biomed. Health Informatics, 2022

<i>DeepStroke</i>: An efficient stroke screening framework for emergency rooms with multimodal adversarial deep learning.
Medical Image Anal., 2022

A personalized image-guided intervention system for peripheral lung cancer on patient-specific respiratory motion model.
Int. J. Comput. Assist. Radiol. Surg., 2022

hDirect-MAP: projection-free single-cell modeling of response to checkpoint immunotherapy.
Briefings Bioinform., 2022

Patcher: Patch Transformers with Mixture of Experts for Precise Medical Image Segmentation.
Proceedings of the Medical Image Computing and Computer Assisted Intervention - MICCAI 2022, 2022

Asymmetry Disentanglement Network for Interpretable Acute Ischemic Stroke Infarct Segmentation in Non-contrast CT Scans.
Proceedings of the Medical Image Computing and Computer Assisted Intervention - MICCAI 2022, 2022

2021
Memory-Augmented Capsule Network for Adaptable Lung Nodule Classification.
IEEE Trans. Medical Imaging, 2021

DeepStroke: An Efficient Stroke Screening Framework for Emergency Rooms with Multimodal Adversarial Deep Learning.
CoRR, 2021

Retrospective study of deep learning to reduce noise in non-contrast head CT images.
Comput. Medical Imaging Graph., 2021

Deep learning powers cancer diagnosis in digital pathology.
Comput. Medical Imaging Graph., 2021

An imageomics and multi-network based deep learning model for risk assessment of liver transplantation for hepatocellular cancer.
Comput. Medical Imaging Graph., 2021

Adaptive Privacy Preserving Deep Learning Algorithms for Medical Data.
Proceedings of the IEEE Winter Conference on Applications of Computer Vision, 2021

LambdaUNet: 2.5D Stroke Lesion Segmentation of Diffusion-Weighted MR Images.
Proceedings of the Medical Image Computing and Computer Assisted Intervention - MICCAI 2021 - 24th International Conference, Strasbourg, France, September 27, 2021

An Intelligent Augmented Lifelike Avatar App for Virtual Physical Examination of Suspected Strokes.
Proceedings of the 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society, 2021

Multimodal Breast Lesion Classification Using Cross-Attention Deep Networks.
Proceedings of the IEEE EMBS International Conference on Biomedical and Health Informatics, 2021

2020
SCOR: A secure international informatics infrastructure to investigate COVID-19.
J. Am. Medical Informatics Assoc., 2020

Evaluation of Inference Attack Models for Deep Learning on Medical Data.
CoRR, 2020

Computational Intelligence Techniques for Combating COVID-19: A Survey.
IEEE Comput. Intell. Mag., 2020

[Guest Editorial].
IEEE Comput. Intell. Mag., 2020

Toward Rapid Stroke Diagnosis with Multimodal Deep Learning.
Proceedings of the Medical Image Computing and Computer Assisted Intervention - MICCAI 2020, 2020

2019
A multi-scale level set method based on local features for segmentation of images with intensity inhomogeneity.
Pattern Recognit., 2019

Preventing inpatient falls with injuries using integrative machine learning prediction: a cohort study.
npj Digit. Medicine, 2019

Driver network as a biomarker: systematic integration and network modeling of multi-omics data to derive driver signaling pathways for drug combination prediction.
Bioinform., 2019

Non-rigid Registration of White Matter Tractography Using Coherent Point Drift Algorithm.
Proceedings of the Multimodal Brain Image Analysis and Mathematical Foundations of Computational Anatomy, 2019

An image informatics pipeline for imaging mass cytometry to characterize the immune landscape in pre- and on-treatment immune therapy and its application in recurrent platinium-resistant epithelial ovarian cancer.
Proceedings of the 2019 IEEE EMBS International Conference on Biomedical & Health Informatics, 2019

2017
Dynamic Respiratory Motion Estimation Using Patch-Based Kernel-PCA Priors for Lung Cancer Radiotherapy.
Proceedings of the Molecular Imaging, Reconstruction and Analysis of Moving Body Organs, and Stroke Imaging and Treatment, 2017

Transductive local fisher discriminant analysis for gene expression profile-based cancer classification.
Proceedings of the 2017 IEEE EMBS International Conference on Biomedical & Health Informatics, 2017

Precise calibration for the coordinates of surgical needle's tip based on transform invariant matrix and spherical constraints.
Proceedings of the 2017 IEEE EMBS International Conference on Biomedical & Health Informatics, 2017

Deep learning analytics for diagnostic support of breast cancer disease management.
Proceedings of the 2017 IEEE EMBS International Conference on Biomedical & Health Informatics, 2017

2016
Transductive Maximum Margin Classification of ADHD Using Resting State fMRI.
Proceedings of the Machine Learning in Medical Imaging - 7th International Workshop, 2016

Data security and privacy management in healthcare applications and clinical data warehouse environment.
Proceedings of the 2016 IEEE-EMBS International Conference on Biomedical and Health Informatics, 2016

When discriminative K-means meets Grassmann manifold: Disease gene identification via a general multi-view clustering method.
Proceedings of the 2016 IEEE-EMBS International Conference on Biomedical and Health Informatics, 2016

DrugMoaMiner: A computational tool for mechanism of action discovery and personalized drug sensitivity prediction.
Proceedings of the 2016 IEEE-EMBS International Conference on Biomedical and Health Informatics, 2016

A three-dimensional medical image segmentation app using graphic theory.
Proceedings of the 2016 IEEE-EMBS International Conference on Biomedical and Health Informatics, 2016

A smartphone app framework for segmented cancer care coordination.
Proceedings of the 2016 IEEE-EMBS International Conference on Biomedical and Health Informatics, 2016

2015
Optimal Drug Prediction From Personal Genomics Profiles.
IEEE J. Biomed. Health Informatics, 2015

Big Data for Health.
IEEE J. Biomed. Health Informatics, 2015

Editorial: Big Data for Health.
IEEE J. Biomed. Health Informatics, 2015

METEOR: An Enterprise Health Informatics Environment to Support Evidence-Based Medicine.
IEEE Trans. Biomed. Eng., 2015

Accurate segmentation of touching cells in multi-channel microscopy images with geodesic distance based clustering.
Neurocomputing, 2015

2014
Guest Editorial: Computational Solutions to Large-Scale Data Management and Analysis in Translational and Personalized Medicine.
IEEE J. Biomed. Health Informatics, 2014

Guest Editorial - Special Issue on '-Omics' Based Companion Diagnostics for Personalized Medicine.
IEEE Trans. Biomed. Circuits Syst., 2014

Enhanced Petri Net: elucidating the pathway-level mechanism of targeted-therapy drugs.
it Inf. Technol., 2014

Fractional anisotropy asymmetry and the side of seizure origin for partial onset-temporal lobe epilepsy.
Comput. Medical Imaging Graph., 2014

DrugComboRanker: drug combination discovery based on target network analysis.
Bioinform., 2014

An Integrated Analytic Pipeline for Identifying and Predicting Genetic Interactions based on Perturbation Data from High Content Double RNAi Screening.
Proceedings of the Annual Conference of the Extreme Science and Engineering Discovery Environment, 2014

Spatial-Temporal Image-Constrained Lung 4D-CT Reconstruction for Radiotherapy Planning.
Proceedings of the Clinical Image-Based Procedures. Translational Research in Medical Imaging, 2014

Estimating Dynamic Lung Images from High-Dimension Chest Surface Motion Using 4D Statistical Model.
Proceedings of the Medical Image Computing and Computer-Assisted Intervention - MICCAI 2014, 2014

2013
A Fast CT and CT-Fluoroscopy Registration Algorithm With Respiratory Motion Compensation for Image-Guided Lung Intervention.
IEEE Trans. Biomed. Eng., 2013

Chapter 17: Bioimage Informatics for Systems Pharmacology.
PLoS Comput. Biol., 2013

A 3D multiscale model of cancer stem cell in tumor development.
BMC Syst. Biol., 2013

A gene signature based method for identifying subtypes and subtype-specific drivers in cancer with an application to medulloblastoma.
BMC Bioinform., 2013

DrugMap Central: an on-line query and visualization tool to facilitate drug repositioning studies.
Bioinform., 2013

Simultaneous Tensor and Fiber Registration (STFR) for Diffusion Tensor Images of the Brain.
Proceedings of the Augmented Reality Environments for Medical Imaging and Computer-Assisted Interventions, 2013

Superpixel-Based Segmentation of Glioblastoma Multiforme from Multimodal MR Images.
Proceedings of the Multimodal Brain Image Analysis - Third International Workshop, 2013

Helical Mode Lung 4D-CT Reconstruction Using Bayesian Model.
Proceedings of the Medical Image Computing and Computer-Assisted Intervention - MICCAI 2013, 2013

A Novel Geodesic Distance Based Clustering Approach to Delineating Boundaries of Touching Cells.
Proceedings of the Advances in Neural Networks - ISNN 2013, 2013

Analyzing grey matter diffusivity of autism in the context of white matter connectivity.
Proceedings of the 10th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2013

A robust semi-automatic approach for ROI segmentation in 3D CT images.
Proceedings of the 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2013

A quantitative analysis of F-actin features and distribution in fluorescence microscopy images to distinguish cells with different modes of motility.
Proceedings of the 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2013

2012
A quantitative analytic pipeline for evaluating neuronal activities by high-throughput synaptic vesicle imaging.
NeuroImage, 2012

A minimally invasive multimodality image-guided (MIMIG) system for peripheral lung cancer intervention and diagnosis.
Comput. Medical Imaging Graph., 2012

Motion correction for cellular-resolution multi-photon fluorescence microscopy imaging of awake head-restrained mice using speed embedded HMM.
Comput. Medical Imaging Graph., 2012

Live-wire-based segmentation of (3D) anatomical structures for image-guided lung interventions.
Proceedings of the Medical Imaging 2012: Image Processing, 2012

A novel approach for three dimensional dendrite spine segmentation and classification.
Proceedings of the Medical Imaging 2012: Image Processing, 2012

Fast CT-CT fluoroscopy registration with respiratory motion compensation for image-guided lung intervention.
Proceedings of the Medical Imaging 2012: Image-Guided Procedures, 2012

Automatic segmentation and centroid detection of skin sensors for lung interventions.
Proceedings of the Medical Imaging 2012: Image-Guided Procedures, 2012

Support vector machine (SVM) active learning for automated Glioblastoma segmentation.
Proceedings of the 9th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2012

Identification of faulty DTI-based sub-networks in autism using network regularized SVM.
Proceedings of the 9th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2012

Three-dimensional dendritic spine detection based on minimal cross-sectional curvature.
Proceedings of the 9th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2012

A 3-dimentional multiscale model to simulate tumor progression in response to interactions between cancer stem cells and tumor microenvironmental factors.
Proceedings of the 6th IEEE International Conference on Systems Biology, 2012

An integrative bioinformatics approach for identifying subtypes and subtype-specific drivers in cancer.
Proceedings of the 2012 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, 2012

Extracting Key Pathways from Gene Signature and Genetic Aberrations in Subtypes of Cancer.
Proceedings of the Computational Intelligence Methods for Bioinformatics and Biostatistics, 2012

2011
A Global Spatial Similarity Optimization Scheme to Track Large Numbers of Dendritic Spines in Time-Lapse Confocal Microscopy.
IEEE Trans. Medical Imaging, 2011

Peak Tree: A New Tool for Multiscale Hierarchical Representation and Peak Detection of Mass Spectrometry Data.
IEEE ACM Trans. Comput. Biol. Bioinform., 2011

Tissue probability map constrained 4D clustering algorithm for increased accuracy and robustness in SerialMR brain image segmentation.
Int. J. Medical Eng. Informatics, 2011

Diffusion tensor-based fast marching for modeling human brain connectivity network.
Comput. Medical Imaging Graph., 2011

An enhanced Petri-net model to predict synergistic effects of pairwise drug combinations from gene microarray data.
Bioinform., 2011

Automated Nuclear Segmentation of Coherent Anti-Stokes Raman Scattering Microscopy Images by Coupling Superpixel Context Information with Artificial Neural Networks.
Proceedings of the Machine Learning in Medical Imaging - Second International Workshop, 2011

Coupling Oriented Hidden Markov Random Field Model with Local Clustering for Segmenting Blood Vessels and Measuring Spatial Structures in Images of Tumor Microenvironment.
Proceedings of the IEEE International Conference on Bioinformatics and Biomedicine, 2011

Quantitative synaptic vesicle imaging for evaluating neuron activities in neurodegenerative diseases.
Proceedings of the Conference Record of the Forty Fifth Asilomar Conference on Signals, 2011

2010
Bayesian peptide peak detection for high resolution TOF mass spectrometry.
IEEE Trans. Signal Process., 2010

Multiple Nuclei Tracking Using Integer Programming for Quantitative Cancer Cell Cycle Analysis.
IEEE Trans. Medical Imaging, 2010

An Automatic and Robust Algorithm of Reestablishment of Digital Dental Occlusion.
IEEE Trans. Medical Imaging, 2010

Fabrication of Localized Surface Plasmon Resonance Fiber Probes Using Ionic Self-Assembled Gold Nanoparticles.
Sensors, 2010

Oriented Markov Random Field Based Dendritic Spine Segmentation for Fluorescence Microscopy Images.
Neuroinformatics, 2010

A neurocomputational method for fully automated 3D dendritic spine detection and segmentation of medium-sized spiny neurons.
NeuroImage, 2010

A local fast marching-based diffusion tensor image registration algorithm by simultaneously considering spatial deformation and tensor orientation.
NeuroImage, 2010

A hybrid approach to automatic clustering of white matter fibers.
NeuroImage, 2010

Joint registration and segmentation of serial lung CT images for image-guided lung cancer diagnosis and therapy.
Comput. Medical Imaging Graph., 2010

Image segmentation by EM-based adaptive pulse coupled neural networks in brain magnetic resonance imaging.
Comput. Medical Imaging Graph., 2010

Semi-supervised drug-protein interaction prediction from heterogeneous biological spaces.
BMC Syst. Biol., 2010

Conditional random pattern model for copy number aberration detection.
BMC Bioinform., 2010

Reconstruction of the neuromuscular junction connectome.
Bioinform., 2010

Optimal Live Cell Tracking for Cell Cycle Study Using Time-Lapse Fluorescent Microscopy Images.
Proceedings of the Machine Learning in Medical Imaging, First International Workshop, 2010

Online 4-D CT Estimation for Patient-Specific Respiratory Motion Based on Real-Time Breathing Signals.
Proceedings of the Medical Image Computing and Computer-Assisted Intervention, 2010

Motion Artifact Correction of Multi-Photon Imaging of Awake Mice Models Using Speed Embedded HMM.
Proceedings of the Medical Image Computing and Computer-Assisted Intervention, 2010

Distinguishing Left or Right Temporal Lobe Epilepsy from Controls Using Fractional Anisotropy Asymmetry Analysis.
Proceedings of the Medical Imaging and Augmented Reality - 5th International Workshop, 2010

A Motion Correction Algorithm for Microendoscope Video Computing in Image-Guided Intervention.
Proceedings of the Medical Imaging and Augmented Reality - 5th International Workshop, 2010

Peripheral Lung Cancer Detection by Vascular Tumor Labeling Using In-Vivo Microendoscopy under Real Time 3D CT Image Guided Intervention.
Proceedings of the Medical Imaging and Augmented Reality - 5th International Workshop, 2010

PICE: prior information constrained evolution for 3-D and 4-D brain tumor segmentation.
Proceedings of the 2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2010

A Minimally Invasive Multimodality Image-Guided (MIMIG) Molecular Imaging System for Peripheral Lung Cancer Intervention and Diagnosis.
Proceedings of the Information Processing in Computer-Assisted Interventions, 2010

Neural stem cell segmentation using local complex phase information.
Proceedings of the International Conference on Image Processing, 2010

2009
A Novel Cell Segmentation Method and Cell Phase Identification Using Markov Model.
IEEE Trans. Inf. Technol. Biomed., 2009

Unraveling the signal-transduction networks in cancer metastasis [Life Sciences].
IEEE Signal Process. Mag., 2009

Recognition and analysis of cell nuclear phases for high-content screening based on morphological features.
Pattern Recognit., 2009

Online phenotype discovery based on minimum classification error model.
Pattern Recognit., 2009

Automated Axon Tracking of 3D Confocal Laser Scanning Microscopy Images Using Guided Probabilistic Region Merging.
Neuroinformatics, 2009

An Automated Pipeline for Dendrite Spine Detection and Tracking of 3D Optical Microscopy Neuron Images of In Vivo Mouse Models.
Neuroinformatics, 2009

Robust 3D reconstruction and identification of dendritic spines from optical microscopy imaging.
Medical Image Anal., 2009

An image score inference system for RNAi genome-wide screening based on fuzzy mixture regression modeling.
J. Biomed. Informatics, 2009

Automated brain tumor segmentation using spatial accuracy-weighted hidden Markov Random Field.
Comput. Medical Imaging Graph., 2009

Conditional random pattern algorithm for LOH inference and segmentation.
Bioinform., 2009

Tissue probability map constrained CLASSIC for increased accuracy and robustness in serial image segmentation.
Proceedings of the Medical Imaging 2009: Image Processing, 2009

Cell Segmentation Using Front Vector Flow Guided Active Contours.
Proceedings of the Medical Image Computing and Computer-Assisted Intervention, 2009

Voles: Vascularity-Oriented Level Set Algorithm for Pulmonary Vessel Segmentation in Image Guided Intervention Therapy.
Proceedings of the 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Boston, MA, USA, June 28, 2009

Online Three-Dimensional Dendritic Spines Mophological Classification Based on Semi-Supervised Learning.
Proceedings of the 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Boston, MA, USA, June 28, 2009

Integrating Multi-Scale Blob/Curvilinear Detector Techniques and Multi-Level Sets for Automated Segmentation of Stem Cell Images.
Proceedings of the 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Boston, MA, USA, June 28, 2009

A Novel Surface-Based Geometric Approach for 3D Dendritic Spine Detection from Multi-Photon Excitation Microscopy Images.
Proceedings of the 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Boston, MA, USA, June 28, 2009

Simultaneous Consideration of Spatial Deformation and Tensor Orientation in Diffusion Tensor Image Registration Using Local Fast Marching Patterns.
Proceedings of the Information Processing in Medical Imaging, 2009

2008
Automatic Segmentation of High-Throughput RNAi Fluorescent Cellular Images.
IEEE Trans. Inf. Technol. Biomed., 2008

Registration of 3-D CT and 2-D Flat Images of Mouse via Affine Transformation.
IEEE Trans. Inf. Technol. Biomed., 2008

Computational Prediction Models for Early Detection of Risk of Cardiovascular Events Using Mass Spectrometry Data.
IEEE Trans. Inf. Technol. Biomed., 2008

Computational Systems Bioinformatics and Bioimaging for Pathway Analysis and Drug Screening.
Proc. IEEE, 2008

An Automated Method for Cell Detection in Zebrafish.
Neuroinformatics, 2008

Workflow and Methods of High-Content Time-Lapse Analysis for Quantifying Intracellular Calcium Signals.
Neuroinformatics, 2008

Reconstruction of central cortical surface from brain MRI images: Method and application.
NeuroImage, 2008

3D Axon Structure Extraction and Analysis in Confocal Fluorescence Microscopy Images.
Neural Comput., 2008

Using nonlinear diffusion and mean shift to detect and connect cross-sections of axons in 3D optical microscopy images.
Medical Image Anal., 2008

Comparison of reversible-jump Markov-chain-Monte-Carlo learning approach with other methods for missing enzyme identification.
J. Biomed. Informatics, 2008

Peak detection using peak tree approach for mass spectrometry data.
Int. J. Hybrid Intell. Syst., 2008

Comparison of Bayesian and regression models in missing enzyme identification.
Int. J. Bioinform. Res. Appl., 2008

Classification and Uncertainty Visualization of Dendritic Spines from Optical Microscopy Imaging.
Comput. Graph. Forum, 2008

Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens.
BMC Bioinform., 2008

Novel cell segmentation and online SVM for cell cycle phase identification in automated microscopy.
Bioinform., 2008

ZFIQ: a software package for zebrafish biology.
Bioinform., 2008

A Novel Method for Cortical Sulcal Fundi Extraction.
Proceedings of the Medical Image Computing and Computer-Assisted Intervention, 2008

Joint Registration and Segmentation of Serial Lung CT Images in Microendoscopy Molecular Image-Guided Therapy.
Proceedings of the Medical Imaging and Augmented Reality, 4th International Workshop, 2008

Classification of Mass Spectrometry Based Protein Markers by Kriging Error Matching.
Proceedings of the Advances in Mass Data Analysis of Images and Signals in Medicine, 2008

Reversible jump MCMC approach for peak identification for stroke SELDI mass spectrometry using mixture model.
Proceedings of the Proceedings 16th International Conference on Intelligent Systems for Molecular Biology (ISMB), 2008

Active microscopic cellular image annotation by superposable graph transduction with imbalanced labels.
Proceedings of the 2008 IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR 2008), 2008

2007
Nanotechnology for genomic signal processing in cancer research - A focus on the genomic signal processing hardware design of the nanotools for cancer ressearch.
IEEE Signal Process. Mag., 2007

Automated Axon Tracking of 3D Confocal Laser Scanning Microscopy Images Using Guided Probabilistic Region Merging.
Neuroinformatics, 2007

Automated neurite extraction using dynamic programming for high-throughput screening of neuron-based assays.
NeuroImage, 2007

Dendritic spine detection using curvilinear structure detector and LDA classifier.
NeuroImage, 2007

Brain tissue segmentation based on DTI data.
NeuroImage, 2007

Automated recognition of cellular phenotypes by support vector machines with feature reduction.
Int. J. Knowl. Based Intell. Eng. Syst., 2007

Least-square conformal brain mapping with spring energy.
Comput. Medical Imaging Graph., 2007

Context based mixture model for cell phase identification in automated fluorescence microscopy.
BMC Bioinform., 2007

Registration of 3D FMT and CT Images of Mouse Via Affine Transformation with Bayesian Iterative Closest Points.
Proceedings of the Advances in Neural Networks, 2007

Detecting Biomarkers for Major Adverse Cardiac Events Using SVM with PLS Feature Selection and Extraction.
Proceedings of the Advances in Neural Networks, 2007

Study of CuO Nanoparticle-induced Cell Death by High Content Cellular Fluorescence Imaging and Analysis.
Proceedings of the International Symposium on Circuits and Systems (ISCAS 2007), 2007

Enabling Technologies in Drug Delivery and Clinical Care.
Proceedings of the International Symposium on Circuits and Systems (ISCAS 2007), 2007

Automated Spine Detection Using Curvilinear Structure Detector and LDA Classifier.
Proceedings of the 2007 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2007

Using Coherent Anti-Stokes Raman Scattering (CARS) to Image Brain Tissues.
Proceedings of the 2007 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2007

Dynamic Local Tracing for 3d Axon Curvilinear Structure Detection from Microscopic Image Stack.
Proceedings of the 2007 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2007

Novel Cell Segmentation and Online Learning Algorithms for Cell Phase Identification in Automated Time-lapse Microscopy.
Proceedings of the 2007 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2007

3-D Centerline Extraction of Axons in Microscopic Stacks for the Study of Motor Neuron Behavior in Developing Muscles.
Proceedings of the 2007 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2007

Reconstruction of Central Cortical Surface from Brain Mri Images: Method and Application.
Proceedings of the 2007 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2007

Segmentation of Touching Cells Using Gradient Flow Tracking.
Proceedings of the 2007 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2007

Deformable Registration of Dti and Spgr Images.
Proceedings of the 2007 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2007

Graph Cut Based Active Contour for Automated Cellular Image Segmentation in High Throughput Rna Interface (rnai) Screening.
Proceedings of the 2007 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2007

Tracking of Migrating Glioma Cells in Feature Space.
Proceedings of the 2007 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2007

A 3D Self-Adjust Region Growing Method for Axon Extraction.
Proceedings of the International Conference on Image Processing, 2007

A New Nonlinear Diffusion Method to Improve Image Quality.
Proceedings of the International Conference on Image Processing, 2007

2006
Automated segmentation, classification, and tracking of cancer cell nuclei in time-lapse microscopy.
IEEE Trans. Biomed. Eng., 2006

Informatics challenges of high-throughput microscopy.
IEEE Signal Process. Mag., 2006

Optical microscopic image processing of dendritic spines morphology.
IEEE Signal Process. Mag., 2006

Taking pictures with E. coli: signal processing using synthetic biology.
IEEE Signal Process. Mag., 2006

Mutual information-based feature selection in studying perturbation of dendritic structure caused by TSC2 inactivation.
Neuroinformatics, 2006

Genotype-image phenotype studies in neuroscience.
Neuroinformatics, 2006

Bayesian variable selection for gene expression modeling with regulatory motif binding sites in neuroinflammatory events.
Neuroinformatics, 2006

76-Space analysis of grey matter diffusivity: Methods and applications.
NeuroImage, 2006

Repulsive force based snake model to segment and track neuronal axons in 3D microscopy image stacks.
NeuroImage, 2006

A computerized cellular imaging system for high content analysis in Monastrol suppressor screens.
J. Biomed. Informatics, 2006

Integrated Algorithms for Image Analysis and Classification of Nuclear Division for High-Content Cell-Cycle Screening.
Int. J. Comput. Intell. Appl., 2006

Protein structure similarity from principle component correlation analysis.
BMC Bioinform., 2006

Gene Selection Using Gaussian Kernel Support Vector Machine Based Recursive Feature Elimination with Adaptive Kernel Width Strategy.
Proceedings of the Rough Sets and Knowledge Technology, First International Conference, 2006

Automated Recognition of Cellular Phenotypes by Support Vector Machines with Feature Reduction.
Proceedings of the Knowledge-Based Intelligent Information and Engineering Systems, 2006

Identification of Cell-Cycle Phases Using Neural Network and Steerable Filter Features.
Proceedings of the Advances in Neural Networks - ISNN 2006, Third International Symposium on Neural Networks, Chengdu, China, May 28, 2006

Stochastic Robust Stability Analysis for Markovian Jump Discrete-Time Delayed Neural Networks with Multiplicative Nonlinear Perturbations.
Proceedings of the Advances in Neural Networks - ISNN 2006, Third International Symposium on Neural Networks, Chengdu, China, May 28, 2006

A shape analysis method to detect dendritic spine in 3D optical microscopy image.
Proceedings of the 2006 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2006

Automated labeling of neurites in fluorescence microscopy images.
Proceedings of the 2006 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2006

Least square conformal mapping with spring energy.
Proceedings of the 2006 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2006

Deformation invariant attribute vector for 3D image registration: method and validation.
Proceedings of the 2006 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2006

Brain tissue segmentation based on DWI/DTI data.
Proceedings of the 2006 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2006

Shape-constrained repulsive snake method to segment and track neurons in 3D microscopy images.
Proceedings of the 2006 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2006

An Effective System for Optical Microscopy Cell Image Segmentation, Tracking and Cell Phase Identification.
Proceedings of the International Conference on Image Processing, 2006

Segmentation of Drosophila RNAI Fluorescence Images Using Level Sets.
Proceedings of the International Conference on Image Processing, 2006

Robust Feature Extraction and Reduction of Mass Spectrometry Data for Cancer Classification.
Proceedings of the Workshops Proceedings of the 6th IEEE International Conference on Data Mining (ICDM 2006), 2006

2005
Emerging biomedical technologies at the micro and nano levels.
IEEE Signal Process. Mag., 2005

Towards Automated Cellular Image Segmentation for RNAi Genome-Wide Screening.
Proceedings of the Medical Image Computing and Computer-Assisted Intervention, 2005

Model the Relationship Between Gene Expression and TFBSs Using a Simplified Neural Network with Bayesian Variable Selection.
Proceedings of the Advances in Neural Networks - ISNN 2005, Second International Symposium on Neural Networks, Chongqing, China, May 30, 2005

Robust Stability for Delayed Neural Networks with Nonlinear Perturbation.
Proceedings of the Advances in Neural Networks - ISNN 2005, Second International Symposium on Neural Networks, Chongqing, China, May 30, 2005

Dynamic sub-cellular behavior study in high content imaging using a multi-threshold approach.
Proceedings of the International Symposium on Circuits and Systems (ISCAS 2005), 2005

A computer-based system to analyze neuron images.
Proceedings of the International Symposium on Circuits and Systems (ISCAS 2005), 2005

Automated dynamic cellular analysis in high throughput drug screens.
Proceedings of the International Symposium on Circuits and Systems (ISCAS 2005), 2005

2004
DBMap: a space-conscious data visualization and knowledge discovery framework for biomedical data warehouse.
IEEE Trans. Inf. Technol. Biomed., 2004

A web-based federated neuroinformatics model for surgical planning and clinical research applications in epilepsy.
Neuroinformatics, 2004

Cancer classification and prediction using logistic regression with Bayesian gene selection.
J. Biomed. Informatics, 2004

High Content Cellular Analysis and Their Applications.
Proceedings of the 3rd International IEEE Computer Society Computational Systems Bioinformatics Conference, 2004

2003
Workflow-enabled distributed component-based information architecture for digital medical imaging enterprises.
IEEE Trans. Inf. Technol. Biomed., 2003

Towards effective and rewarding data sharing.
Neuroinformatics, 2003

An XML message broker framework for exchange and integration of microarray data.
Bioinform., 2003

Integrating Bioinformatics Advances into Disease Management Systems to Improve Quality of Care.
Proceedings of the 2nd IEEE Computer Society Bioinformatics Conference, 2003

Quantitative effectiveness analysis of radiation therapy in temporal lobe epilepsy using diffusion tensor imaging techniques.
Proceedings of the CARS 2003. Computer Assisted Radiology and Surgery. Proceedings of the 17th International Congress and Exhibition, 2003

2002
Application of Information Technology: Design and Applications of a Multimodality Image Data Warehouse Framework.
J. Am. Medical Informatics Assoc., 2002

Storage, data management, and retrieval in bioinformatics.
Proceedings of the Storage and Retrieval for Media Databases 2002, 2002

2001
Human Brain Program Research Progress in Biomedical Imaging/ Neuroscience, 2001.
J. Am. Medical Informatics Assoc., 2001

Human Brain Program Research Progress in Bioinformatics/ Neuroinformatics.
J. Am. Medical Informatics Assoc., 2001

1999
A digital library for biomedical imaging on the Internet.
IEEE Commun. Mag., 1999

Digital Teaching Files in Diagnostic Imaging.
IEEE Computer Graphics and Applications, 1999

1998
Security for the digital information age of medicine: Issues, applications, and implementation.
J. Digit. Imaging, 1998

1997
Coping with conflict in cooperative knowledge-based systems.
IEEE Trans. Syst. Man Cybern. Part A, 1997

Issues and Applications of Digital Library Technology in Biomedical Imaging.
Int. J. Digit. Libr., 1997

Editorial.
Int. J. Digit. Libr., 1997

Networked Multimedia for Medical Imaging.
IEEE Multim., 1997

Design of a multimedia system for multispecialty medical conferences.
Proceedings of the Medical Imaging 1997: Image Display, 1997

Medical workstation design: enhancing graphical interface with 3D anatomical atlas.
Proceedings of the Medical Imaging 1997: Image Display, 1997

1996
A hospital integrated framework for multimodality image base management.
IEEE Trans. Syst. Man Cybern. Part A, 1996

A Deductive Object-Oriented Database System for Situated Inference in Law.
IEEE Trans. Knowl. Data Eng., 1996

Research Paper: A Cryptologic Based Trust Center for Medical Images.
J. Am. Medical Informatics Assoc., 1996

Multimodal image fusion for noninvasive epilepsy surgery planning.
IEEE Computer Graphics and Applications, 1996

1994
An Open System Knowledge Framework and its Bridge Evaluation Application.
IEEE Trans. Syst. Man Cybern. Syst., 1994

Preference-Based Decision Making for Cooperative Knowledge-Based Systems.
ACM Trans. Inf. Syst., 1994

1993
COSMO: a communication scheme for cooperative knowledge-based systems.
IEEE Trans. Syst. Man Cybern., 1993

Design Guidelines for Object-Oriented Deductive Systems.
IEEE Trans. Knowl. Data Eng., 1993

A Multi-Level Description Scheme of Protein Conformation.
Proceedings of the 1st International Conference on Intelligent Systems for Molecular Biology, 1993

A Product Assembly and Restoration Planning System for Ecologically Conscious Factories.
Proceedings of the Information Infrastructure Systems for Manufacturing, 1993

A Computational Model for Trial Reasoning.
Proceedings of the Fourth International Conference on Artificial intelligence and Law, 1993

1989
Object Formation in A Hybrid Knowledge Representation.
Proceedings of the SEKE'89, 1989

Extending knowledge-based systems through closely-coupled graphics and windows.
Proceedings of the Second International Conference on Industrial & Engineering Applications of Artificial Intelligence & Expert Systems, IEA/AIE 1989, June 6-9, 1989, Tullahoma, TN, USA, 1989


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