Stephan C. Schürer

According to our database, Stephan C. Schürer authored at least 37 papers between 2005 and 2023.

Collaborative distances:

• Dijkstra number of four.
• Erdős number of four.

2023

An extension of the BioAssay Ontology to include pharmacokinetic/pharmacodynamic terminology for the enrichment of scientific workflows.

Steve Penn, Jane Lomax, Anneli Karlsson, Vincent Antonucci, Carl-Dieter Zachmann, Samantha Kanza, Stephan C. Schürer, John Turner

J. Biomed. Semant., December, 2023

Correction: AI-Assisted chemical probe discovery for the understudied Calcium-Calmodulin Dependent Kinase, PNCK.

Derek J. Essegian, Valery Chavez, Rabia Khurshid, Jaime R. Merchan, Stephan C. Schürer

PLoS Comput. Biol., November, 2023

Pharos 2023: an integrated resource for the understudied human proteome.

Keith J. Kelleher, Timothy Sheils, Stephen L. Mathias, Jeremy J. Yang, Vincent T. Metzger, Vishal B. Siramshetty, Dac-Trung Nguyen, Lars Juhl Jensen, Dusica Vidovic, Stephan C. Schürer, Jayme Holmes, Karlie R. Sharma, Ajay Pillai, Cristian Bologa, Jeremy S. Edwards, Ewy A. Mathé, Tudor I. Oprea

Nucleic Acids Res., January, 2023

AI-Assisted chemical probe discovery for the understudied Calcium-Calmodulin Dependent Kinase, PNCK.

Derek J. Essegian, Valery Chavez, Rabia Khurshid, Jaime R. Merchan, Stephan C. Schürer

PLoS Comput. Biol., 2023

2022

The Clinical Kinase Index (CKI): A user friendly application to prioritize kinases as prospective cancer drug targets.

Rimpi Khurana, Stephan C. Schürer

Softw. Impacts, 2022

SigCom LINCS: data and metadata search engine for a million gene expression signatures.

John Erol Evangelista, Daniel J. B. Clarke, Zhuorui Xie, Alexander Lachmann, Minji Jeon, Kerwin Chen, Kathleen M. Jagodnik, Sherry L. Jenkins, Maxim V. Kuleshov, Megan L. Wojciechowicz, Stephan C. Schürer, Mario Medvedovic, Avi Ma'ayan

Nucleic Acids Res., 2022

2021

TCRD and Pharos 2021: mining the human proteome for disease biology.

Timothy Sheils, Stephen L. Mathias, Keith J. Kelleher, Vishal B. Siramshetty, Dac-Trung Nguyen, Cristian Bologa, Lars Juhl Jensen, Dusica Vidovic, Amar Koleti, Stephan C. Schürer, Anna Waller, Jeremy J. Yang, Jayme Holmes, Giovanni Bocci, Noel Southall, Poorva Dharkar, Ewy A. Mathé, Anton Simeonov, Tudor I. Oprea

Nucleic Acids Res., 2021

2020

LINCS Data Portal 2.0: next generation access point for perturbation-response signatures.

Vasileios Stathias, John Paul Turner, Amar Koleti, Dusica Vidovic, Daniel J. Cooper, Mehdi Fazel-Najafabadi, Marcin Pilarczyk, Raymond Terryn, Caty Chung, Afoma Umeano, Daniel J. B. Clarke, Alexander Lachmann, John Erol Evangelista, Avi Ma'ayan, Mario Medvedovic, Stephan C. Schürer

Nucleic Acids Res., 2020

piNET: a versatile web platform for downstream analysis and visualization of proteomics data.

Behrouz Shamsaei, Szymon Chojnacki, Marcin Pilarczyk, Mehdi Fazel-Najafabadi, Wen Niu, Chuming Chen, Karen Ross, Andrea Matlock, Jeremy Muhlich, Somchai Chutipongtanate, Jie Zheng, John Turner, Dusica Vidovic, Jake Jaffe, Michael J. MacCoss, Cathy Wu, Ajay Pillai, Avi Ma'ayan, Stephan C. Schürer, Michal Kouril, Mario Medvedovic, Jarek Meller

Nucleic Acids Res., 2020

2019

DrugCentral 2018: an update.

Oleg Ursu, Jayme Holmes, Cristian Bologa, Jeremy J. Yang, Stephen L. Mathias, Vasileios Stathias, Dac-Trung Nguyen, Stephan C. Schürer, Tudor I. Oprea

Nucleic Acids Res., 2019

OSCI: standardized stem cell ontology representation and use cases for stem cell investigation.

Yongqun He, William D. Duncan, Daniel J. Cooper, Jens Hansen, Ravi Iyengar, Edison Ong, Kendal Walker, Omar Tibi, Sam Smith, Lucas M. Serra, Jie Zheng, Sirarat Sarntivijai, Stephan C. Schürer, K. Sue O'Shea, Alexander D. Diehl

BMC Bioinform., 2019

2018

Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data.

Amar Koleti, Raymond Terryn, Vasileios Stathias, Caty Chung, Daniel J. Cooper, John Paul Turner, Dusica Vidovic, Michele Forlin, Tanya T. Kelley, Alessandro D'Urso, Bryce K. Allen, Denis Torre, Kathleen M. Jagodnik, Lily Wang, Sherry L. Jenkins, Christopher Mader, Wen Niu, Mehdi Fazel, Naim Al Mahi, Marcin Pilarczyk, Nicholas A. Clark, Behrouz Shamsaei, Jarek Meller, Juozas Vasiliauskas, John Reichard, Mario Medvedovic, Avi Ma'ayan, Ajay Pillai, Stephan C. Schürer

Nucleic Acids Res., 2018

CEDAR: Semantic Web Technology to Support Open Science.

Mark A. Musen, Susanna-Assunta Sansone, Kei-Hoi Cheung, Steven H. Kleinstein, Morgan Crafts, Stephan C. Schürer, John Graybeal

Proceedings of the Companion of the The Web Conference 2018 on The Web Conference 2018, 2018

A Gene Family-led Meta-Analysis of Drug-Target Interactions.

Qiong Cheng, Saurabh Mehta, Stephan C. Schürer

Proceedings of the IEEE International Conference on Bioinformatics and Biomedicine, 2018

2017

Pharos: Collating protein information to shed light on the druggable genome.

Dac-Trung Nguyen, Stephen L. Mathias, Cristian Bologa, Søren Brunak, Nicolas F. Fernandez, Anna Gaulton, Anne Hersey, Jayme Holmes, Lars Juhl Jensen, Anneli Karlsson, Guixia Liu, Avi Ma'ayan, Geetha Mandava, Subramani Mani, Saurabh Mehta, John P. Overington, Juhee Patel, Andrew D. Rouillard, Stephan C. Schürer, Timothy Sheils, Anton Simeonov, Larry A. Sklar, Noel Southall, Oleg Ursu, Dusica Vidovic, Anna Waller, Jeremy J. Yang, Ajit Jadhav, Tudor I. Oprea, Rajarshi Guha

Nucleic Acids Res., 2017

Developing a framework for digital objects in the Big Data to Knowledge (BD2K) commons: Report from the Commons Framework Pilots workshop.

Kathleen M. Jagodnik, Simon Koplev, Sherry L. Jenkins, Lucila Ohno-Machado, Benedict Paten, Stephan C. Schürer, Michel Dumontier, Ruben Verborgh, Alex Bui, Peipei Ping, Neil J. McKenna, Ravi K. Madduri, Ajay Pillai, Avi Ma'ayan

J. Biomed. Informatics, 2017

Ontological representation, integration, and analysis of LINCS cell line cells and their cellular responses.

Edison Ong, Jiangan Xie, Zhaohui Ni, Qingping Liu, Sirarat Sarntivijai, Yu Lin, Daniel J. Cooper, Raymond Terryn, Vasileios Stathias, Caty Chung, Stephan C. Schürer, Yongqun He

BMC Bioinform., 2017

Drug target ontology to classify and integrate drug discovery data.

Yu Lin, Saurabh Mehta, Hande Küçük-McGinty, John Paul Turner, Dusica Vidovic, Michele Forlin, Amar Koleti, Dac-Trung Nguyen, Lars Juhl Jensen, Rajarshi Guha, Stephen L. Mathias, Oleg Ursu, Vasileios Stathias, Jianbin Duan, Nooshin Nabizadeh, Caty Chung, Christopher Mader, Ubbo Visser, Jeremy J. Yang, Cristian Bologa, Tudor I. Oprea, Stephan C. Schürer

J. Biomed. Semant., 2017

TIN-X: target importance and novelty explorer.

Daniel Cannon, Jeremy J. Yang, Stephen L. Mathias, Oleg Ursu, Subramani Mani, Anna Waller, Stephan C. Schürer, Lars Juhl Jensen, Larry A. Sklar, Cristian Bologa, Tudor I. Oprea

Bioinform., 2017

The SmartAPI Ecosystem for Making Web APIs FAIR.

Shima Dastgheib, Trish Whetzel, Amrapali Zaveri, Cyrus Afrasiabi, Pedro Assis, Paul Avillach, Kathleen M. Jagodnik, Gabor Korodi, Marcin Pilarczyk, Jeff de Pons, Stephan C. Schürer, Raymond Terryn, Ruben Verborgh, Chunlei Wu, Michel Dumontier

Proceedings of the ISWC 2017 Posters & Demonstrations and Industry Tracks co-located with 16th International Semantic Web Conference (ISWC 2017), Vienna, Austria, October 23rd - to, 2017

Learning reference-enriched approach towards large scale active ontology alignment and integration.

Qiong Cheng, Oleg Ursu, Tudor I. Oprea, Stephan C. Schürer

Proceedings of the 2017 IEEE International Conference on Bioinformatics and Biomedicine, 2017

The ontology reference model for visual selectivity analysis in drug-target interactions.

Qiong Cheng, Felix A. Lopez, Celia Duran, Christopher Camarillo, Tudor I. Oprea, Stephan C. Schürer

Proceedings of the 2017 IEEE International Conference on Bioinformatics and Biomedicine, 2017

2016

The Cell Line Ontology Integration and Analysis of the Knowledge of LINCS Cell Lines.

Edison Ong, Jiangan Xie, Zhaohui Ni, Qingping Liu, Yu Lin, Vasileios Stathias, Caty Chung, Stephan C. Schürer, Yongqun He

Proceedings of the Joint International Conference on Biological Ontology and BioCreative, 2016

Building Concordant Ontologies for Drug Discovery.

Hande Küçük-McGinty, Saurabh Mehta, Yu Lin, Nooshin Nabizadeh, Vasileios Stathias, Dusica Vidovic, Amar Koleti, Christopher Mader, Jianbin Duan, Ubbo Visser, Stephan C. Schürer

Proceedings of the Joint International Conference on Biological Ontology and BioCreative, 2016

2015

BioAssay Research Database (BARD): chemical biology and probe-development enabled by structured metadata and result types.

E. A. Howe, Andrea de Souza, David L. Lahr, S. Chatwin, Philip Montgomery, B. R. Alexander, Dac-Trung Nguyen, Yasel Cruz, D. A. Stonich, G. Walzer, J. T. Rose, Shaita C. Picard, Zihan Liu, Jamie N. Rose, X. Xiang, Jacob K. Asiedu, D. Durkin, J. Levine, J. J. Yang, Stephan C. Schürer, John C. Braisted, Noel Southall, Mark R. Southern, T. D. Y. Chung, Steve Brudz, C. Tanega, Stuart L. Schreiber, Joshua A. Bittker, Rajarshi Guha, Paul A. Clemons

Nucleic Acids Res., 2015

2014

CLO: The cell line ontology.

Sirarat Sarntivijai, Yu Lin, Zuoshuang Xiang, Terrence F. Meehan, Alexander D. Diehl, Uma D. Vempati, Stephan C. Schürer, Chao Pang, James Malone, Helen E. Parkinson, Yue Liu, Terue Takatsuki, Kaoru Saijo, Hiroshi Masuya, Yukio Nakamura, Matthew H. Brush, Melissa A. Haendel, Jie Zheng, Christian J. Stoeckert Jr., Bjoern Peters, Christopher J. Mungall, Thomas E. Carey, David J. States, Brian D. Athey, Yongqun He

J. Biomed. Semant., 2014

Evolving BioAssay Ontology (BAO): modularization, integration and applications.

Saminda Abeyruwan, Uma D. Vempati, Hande Küçük-McGinty, Ubbo Visser, Amar Koleti, Ahsan Mir, Kunie Sakurai, Caty Chung, Joshua A. Bittker, Paul A. Clemons, Steve Brudz, Anosha Siripala, Arturo J. Morales, Martin Romacker, David Twomey, Svetlana Bureeva, Vance P. Lemmon, Stephan C. Schürer

J. Biomed. Semant., 2014

2013

Kinome-wide Activity Modeling from Diverse Public High-Quality Data Sets.

Stephan C. Schürer, Steven M. Muskal

J. Chem. Inf. Model., 2013

GPCR ontology: development and application of a G protein-coupled receptor pharmacology knowledge framework.

Magdalena Przydzial, Barun Bhhatarai, Amar Koleti, Uma Vempati, Stephan C. Schürer

Bioinform., 2013

PrOntoLearn: Unsupervised Lexico-Semantic Ontology Generation Using Probabilistic Methods.

Saminda Abeyruwan, Ubbo Visser, Vance P. Lemmon, Stephan C. Schürer

Proceedings of the Uncertainty Reasoning for the Semantic Web II, 2013

2012

Novel Kinase Inhibitors by Reshuffling Ligand Functionalities Across the Human Kinome.

Dusica Vidovic, Steven M. Muskal, Stephan C. Schürer

J. Chem. Inf. Model., 2012

2011

Distinct functional and conformational states of the human lymphoid tyrosine phosphatase catalytic domain can be targeted by choice of the inhibitor chemotype.

Dusica Vidovic, Yuli Xie, Alison Rinderspacher, Shi-Xian Deng, Donald W. Landry, Caty Chung, Deborah H. Smith, Lutz Tautz, Stephan C. Schürer

J. Comput. Aided Mol. Des., 2011

BioAssay Ontology (BAO): A Semantic Description of Bioassays and High-Throughput Screening Results.

Ubbo Visser, Saminda Abeyruwan, Uma Vempati, Robin P. Smith, Vance P. Lemmon, Stephan C. Schürer

BMC Bioinform., 2011

Bioassay Ontology to Describe High-Throughput Screening Assays and their Results.

Uma Vempati, Ubbo Visser, Saminda Abeyruwan, Kunie Sakurai, Magdalena Przydzial, Caty Chung, Robin P. Smith, Amar Koleti, Christopher Mader, Vance P. Lemmon, Stephan C. Schürer

Proceedings of the 2nd International Conference on Biomedical Ontology, 2011

Cell Line Ontology: Redesigning the Cell Line Knowledgebase to Aid Integrative Translational Informatics.

Sirarat Sarntivijai, Zuoshuang Xiang, Terrence F. Meehan, Alexander D. Diehl, Uma Vempati, Stephan C. Schürer, Chao Pang, James Malone, Helen E. Parkinson, Brian D. Athey, Yongqun He

Proceedings of the 2nd International Conference on Biomedical Ontology, 2011

2008

Utilizing high throughput screening data for predictive toxicology models: protocols and application to MLSCN assays.

Rajarshi Guha, Stephan C. Schürer

J. Comput. Aided Mol. Des., 2008

2005

Prospective Exploration of Synthetically Feasible, Medicinally Relevant Chemical Space.

Stephan C. Schürer, Prashant Tyagi, Steven M. Muskal

J. Chem. Inf. Model., 2005