Steffen Klamt

Orcid: 0000-0003-2563-7561

According to our database1, Steffen Klamt authored at least 53 papers between 2001 and 2024.

Collaborative distances:
  • Dijkstra number2 of five.
  • Erdős number3 of four.

Timeline

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Bibliography

2024
Experimentally implemented dynamic optogenetic optimization of ATPase expression using knowledge-based and Gaussian-process-supported models.
CoRR, 2024

2023
Balancing biomass reaction stoichiometry and measured fluxes in flux balance analysis.
Bioinform., October, 2023

Towards a modeling, optimization and predictive control framework for fed-batch metabolic cybergenetics.
CoRR, 2023

2022
StrainDesign: a comprehensive Python package for computational design of metabolic networks.
Bioinform., October, 2022

CNApy: a CellNetAnalyzer GUI in Python for analyzing and designing metabolic networks.
Bioinform., 2022

2021
Designing microbial communities to maximize the thermodynamic driving force for the production of chemicals.
PLoS Comput. Biol., 2021

2020
An extended and generalized framework for the calculation of metabolic intervention strategies based on minimal cut sets.
PLoS Comput. Biol., 2020

Speeding up the core algorithm for the dual calculation of minimal cut sets in large metabolic networks.
BMC Bioinform., 2020

Automatic construction of metabolic models with enzyme constraints.
BMC Bioinform., 2020

2019
Designing Optimal Experiments to Discriminate Interaction Graph Models.
IEEE ACM Trans. Comput. Biol. Bioinform., 2019

RedCom: A strategy for reduced metabolic modeling of complex microbial communities and its application for analyzing experimental datasets from anaerobic digestion.
PLoS Comput. Biol., 2019

Characterizing and ranking computed metabolic engineering strategies.
Bioinform., 2019

2018
Generalizing Diffuse Interface Methods on Graphs: Nonsmooth Potentials and Hypergraphs.
SIAM J. Appl. Math., 2018

OptMDFpathway: Identification of metabolic pathways with maximal thermodynamic driving force and its application for analyzing the endogenous CO2 fixation potential of Escherichia coli.
PLoS Comput. Biol., 2018

2017
From elementary flux modes to elementary flux vectors: Metabolic pathway analysis with arbitrary linear flux constraints.
PLoS Comput. Biol., 2017

2016
TRaCE+: Ensemble inference of gene regulatory networks from transcriptional expression profiles of gene knock-out experiments.
BMC Bioinform., 2016

Exact quantification of cellular robustness in genome-scale metabolic networks.
Bioinform., 2016

2015
Disentangling the Complexity of HGF Signaling by Combining Qualitative and Quantitative Modeling.
PLoS Comput. Biol., 2015

An algorithm for the reduction of genome-scale metabolic network models to meaningful core models.
BMC Syst. Biol., 2015

Extended notions of sign consistency to relate experimental data to signaling and regulatory network topologies.
BMC Bioinform., 2015

Genome-scale strain designs based on regulatory minimal cut sets.
Bioinform., 2015

2014
Enumeration of Smallest Intervention Strategies in Genome-Scale Metabolic Networks.
PLoS Comput. Biol., 2014

A model integration approach linking signalling and gene-regulatory logic with kinetic metabolic models.
Biosyst., 2014

Stoichiometric and Constraint-Based Analysis of Biochemical Reaction Networks.
Proceedings of the Large-Scale Networks in Engineering and Life Sciences, 2014

2013
Detecting and Removing Inconsistencies between Experimental Data and Signaling Network Topologies Using Integer Linear Programming on Interaction Graphs.
PLoS Comput. Biol., 2013

Reconstruction of large-scale regulatory networks based on perturbation graphs and transitive reduction: improved methods and their evaluation.
BMC Syst. Biol., 2013

SBML qualitative models: a model representation format and infrastructure to foster interactions between qualitative modelling formalisms and tools.
BMC Syst. Biol., 2013

Comparison and improvement of algorithms for computing minimal cut sets.
BMC Bioinform., 2013

An effective framework for reconstructing gene regulatory networks from genetical genomics data.
Bioinform., 2013

2012
Minimal cut sets in a metabolic network are elementary modes in a dual network.
Bioinform., 2012

2011
Metabolic network modeling of redox balancing and biohydrogen production in purple nonsulfur bacteria.
BMC Syst. Biol., 2011

An application programming interface for CellNetAnalyzer.
Biosyst., 2011

Special issue: Integration of OMICs datasets into Metabolic Pathway Analysis.
Biosyst., 2011

2010
From Binary to Multivalued to Continuous Models: The Lac Operon as a Case Study.
J. Integr. Bioinform., 2010

Computing Combinatorial Intervention Strategies and Failure Modes in Signaling Networks.
J. Comput. Biol., 2010

TRANSWESD: inferring cellular networks with transitive reduction.
Bioinform., 2010

CASOP GS: Computing Intervention Strategies Targeted at Production Improvement in Genome-scale Metabolic Networks.
Proceedings of the German Conference on Bioinformatics 2010, 2010

2009
The Logic of EGFR/ErbB Signaling: Theoretical Properties and Analysis of High-Throughput Data.
PLoS Comput. Biol., 2009

Hypergraphs and Cellular Networks.
PLoS Comput. Biol., 2009

Transforming Boolean models to continuous models: methodology and application to T-cell receptor signaling.
BMC Syst. Biol., 2009

Computing paths and cycles in biological interaction graphs.
BMC Bioinform., 2009

2008
Computing Knock-Out Strategies in Metabolic Networks.
J. Comput. Biol., 2008

Host-pathogen systems biology: logical modelling of hepatocyte growth factor and Helicobacter pylori induced c-Met signal transduction.
BMC Syst. Biol., 2008

2007
A Logical Model Provides Insights into T Cell Receptor Signaling.
PLoS Comput. Biol., 2007

Structural and functional analysis of cellular networks with CellNetAnalyzer.
BMC Syst. Biol., 2007

2006
Visual setup of logical models of signaling and regulatory networks with ProMoT.
BMC Bioinform., 2006

A methodology for the structural and functional analysis of signaling and regulatory networks.
BMC Bioinform., 2006

2004
Workbench zur Modellbildung, Simulation und Analyse zellulärer Systeme (Workbench for Model Set Up, Simulation, and Analysis of Cellular Systems).
it Inf. Technol., 2004

Computation of elementary modes: a unifying framework and the new binary approach.
BMC Bioinform., 2004

Minimal cut sets in biochemical reaction networks.
Bioinform., 2004

2003
FluxAnalyzer: exploring structure, pathways, and flux distributions in metabolic networks on interactive flux maps.
Bioinform., 2003

Making predictions about robustness and flexibility from metabolic network structure.
Proceedings of the German Conference on Bioinformatics, 2003

2001
FluxAnalyzer: A Graphical User Interface for Analyzing Structural Properties and Fluxes in Balanced Metabolic Networks.
Proceedings of the Computer science and biology: Proceedings of the German Conference on Bioinformatics, 2001


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