Pedro Alexandrino Fernandes

Orcid: 0000-0003-2748-4722

According to our database1, Pedro Alexandrino Fernandes authored at least 23 papers between 2003 and 2024.

Collaborative distances:
  • Dijkstra number2 of five.
  • Erdős number3 of four.

Timeline

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Bibliography

2024
DszA Catalyzes C-S Bond Cleavage through N<sup>5</sup>-Hydroperoxyl Formation.
J. Chem. Inf. Model., 2024

2023
Deciphering the Catalytic Mechanism of Virginiamycin B Lyase with Multiscale Methods and Molecular Dynamics Simulations.
J. Chem. Inf. Model., October, 2023

Unraveling the Reaction Mechanism of Russell's Viper Venom Factor X Activator: A Paradigm for the Reactivity of Zinc Metalloproteinases?
J. Chem. Inf. Model., July, 2023

Engineering DszC Mutants from Transition State Macrodipole Considerations and Evolutionary Sequence Analysis.
J. Chem. Inf. Model., 2023

2022
Transmembrane Protease Serine 2 Proteolytic Cleavage of the SARS-CoV-2 Spike Protein: A Mechanistic Quantum Mechanics/Molecular Mechanics Study to Inspire the Design of New Drugs To Fight the COVID-19 Pandemic.
J. Chem. Inf. Model., 2022

Role of Enzyme and Active Site Conformational Dynamics in the Catalysis by α-Amylase Explored with QM/MM Molecular Dynamics.
J. Chem. Inf. Model., 2022

2020
A Computational and Modeling Study of the Reaction Mechanism of Staphylococcus aureus Monoglycosyltransferase Reveals New Insights on the GT51 Family of Enzymes.
J. Chem. Inf. Model., 2020

Assessing the validity of DLPNO-CCSD(T) in the calculation of activation and reaction energies of ubiquitous enzymatic reactions.
J. Comput. Chem., 2020

2017
New Parameters for Higher Accuracy in the Computation of Binding Free Energy Differences upon Alanine Scanning Mutagenesis on Protein-Protein Interfaces.
J. Chem. Inf. Model., 2017

2016
Calculation of distribution coefficients in the SAMPL5 challenge from atomic solvation parameters and surface areas.
J. Comput. Aided Mol. Des., 2016

2015
A Weighted Constraint Optimization Approach to the Nurse Scheduling Problem.
Proceedings of the 18th IEEE International Conference on Computational Science and Engineering, 2015

2013
Comparative analysis of the performance of commonly available density functionals in the determination of geometrical parameters for copper complexes.
J. Comput. Chem., 2013

2010
Protein-protein docking dealing with the unknown.
J. Comput. Chem., 2010

2009
Comparative analysis of the performance of commonly available density functionals in the determination of geometrical parameters for zinc complexes.
J. Comput. Chem., 2009

Role of the variable active site residues in the function of thioredoxin family oxidoreductases.
J. Comput. Chem., 2009

2008
Mechanistic studies on the formation of glycosidase-substrate and glycosidase-inhibitor covalent intermediates.
J. Comput. Chem., 2008

2007
Theoretical studies on farnesyl transferase: Evidence for thioether product coordination to the active-site zinc sphere.
J. Comput. Chem., 2007

Computational alanine scanning mutagenesis - An improved methodological approach.
J. Comput. Chem., 2007

2006
Determination of the pKa between the active site cysteines of thioredoxin and DsbA.
J. Comput. Chem., 2006

2004
Mechanism for ribonucleotide reductase inactivation by the anticancer drug gemcitabine.
J. Comput. Chem., 2004

Theoretical study of ribonucleotide reductase mechanism-based inhibition by 2-azido-2-deoxyribonucleoside 5-diphosphates.
J. Comput. Chem., 2004

Ribonucleotide activation by enzyme ribonucleotide reductase: Understanding the role of the enzyme.
J. Comput. Chem., 2004

2003
New designs for MRI contrast agents.
J. Comput. Aided Mol. Des., 2003


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