Luonan Chen

Orcid: 0000-0002-3960-0068

According to our database1, Luonan Chen authored at least 192 papers between 1995 and 2024.

Collaborative distances:

Timeline

Legend:

Book 
In proceedings 
Article 
PhD thesis 
Dataset
Other 

Links

On csauthors.net:

Bibliography

2024
Dynamical causality under invisible confounders.
CoRR, 2024

CIDER: Counterfactual-Invariant Diffusion-based GNN Explainer for Causal Subgraph Inference.
CoRR, 2024

Deciphering interventional dynamical causality from non-intervention systems.
CoRR, 2024

Multi-modal domain adaptation for revealing spatial functional landscape from spatially resolved transcriptomics.
Briefings Bioinform., 2024

Survival Analysis of Histopathological Image Based on a Pretrained Hypergraph Model of Spatial Transcriptomics Data.
Proceedings of the Medical Image Computing and Computer Assisted Intervention - MICCAI 2024, 2024

2023
Contrastively generative self-expression model for single-cell and spatial multimodal data.
Briefings Bioinform., September, 2023

Single-cell causal network inferred by cross-mapping entropy.
Briefings Bioinform., September, 2023

Why Increase of Heterogeneity Signals Pre-Deterioration During Tumor Progression: A Unified Mathematical Model.
SIAM J. Appl. Math., April, 2023

Predicting time series by data-driven spatiotemporal information transformation.
Inf. Sci., April, 2023

Cell-type annotation with accurate unseen cell-type identification using multiple references.
PLoS Comput. Biol., 2023

2022
Spatiotemporal Transformer Neural Network for Time-Series Forecasting.
Entropy, November, 2022

Extracting ROI-Based Contourlet Subband Energy Feature From the sMRI Image for Alzheimer's Disease Classification.
IEEE ACM Trans. Comput. Biol. Bioinform., 2022

Brain-inspired chaotic backpropagation for MLP.
Neural Networks, 2022

Predicting high-dimensional time series data with spatial, temporal and global information.
Inf. Sci., 2022

Time Series Prediction by Multi-task GPR with Spatiotemporal Information Transformation.
CoRR, 2022

Detection of Alzheimer's disease using features of brain region-of-interest-based individual network constructed with the sMRI image.
Comput. Medical Imaging Graph., 2022

Identifying network biomarkers of cancer by sample-specific differential network.
BMC Bioinform., 2022

A comprehensive update on CIDO: the community-based coronavirus infectious disease ontology.
J. Biomed. Semant., 2022

Deep latent space fusion for adaptive representation of heterogeneous multi-omics data.
Briefings Bioinform., 2022

Transcriptome analysis method based on differential distribution evaluation.
Briefings Bioinform., 2022

Detecting the critical states during disease development based on temporal network flow entropy.
Briefings Bioinform., 2022

2021
Deep cross-omics cycle attention model for joint analysis of single-cell multi-omics data.
Bioinform., November, 2021

Alzheimer's disease classification using features extracted from nonsubsampled contourlet subband-based individual networks.
Neurocomputing, 2021

c-CSN: Single-cell RNA Sequencing Data Analysis by Conditional Cell-specific Network.
Genom. Proteom. Bioinform., 2021

Advanced Single-cell Omics Technologies and Informatics Tools for Genomics, Proteomics, and Bioinformatics Analysis.
Genom. Proteom. Bioinform., 2021

Spatiotemporal convolutional network for time-series prediction and causal inference.
CoRR, 2021

Revealing dynamic regulations and the related key proteins of myeloma-initiating cells by integrating experimental data into a systems biological model.
Bioinform., 2021

Deep-joint-learning analysis model of single cell transcriptome and open chromatin accessibility data.
Briefings Bioinform., 2021

Disease characterization using a partial correlation-based sample-specific network.
Briefings Bioinform., 2021

2020
Efficient Mining Multi-Mers in a Variety of Biological Sequences.
IEEE ACM Trans. Comput. Biol. Bioinform., 2020

Quantifying Direct Dependencies in Biological Networks by Multiscale Association Analysis.
IEEE ACM Trans. Comput. Biol. Bioinform., 2020

A Branch Point on Differentiation Trajectory is the Bifurcating Event Revealed by Dynamical Network Biomarker Analysis of Single-Cell Data.
IEEE ACM Trans. Comput. Biol. Bioinform., 2020

ZokorDB: tissue specific regulatory network annotation for non-coding elements of plateau zokor.
Quant. Biol., 2020

Critical transitions and tipping points in EMT.
Quant. Biol., 2020

A plausible accelerating function of intermediate states in cancer metastasis.
PLoS Comput. Biol., 2020

Kinase-substrate Edge Biomarkers Provide A More Accurate Prognostic Prediction in ER-negative Breast Cancer.
Genom. Proteom. Bioinform., 2020

Identification of Key Genes for the Ultrahigh Yield of Rice Using Dynamic Cross-tissue Network Analysis.
Genom. Proteom. Bioinform., 2020

Single-sample landscape entropy reveals the imminent phase transition during disease progression.
Bioinform., 2020

Corrigendum to: Single-sample landscape entropy reveals the imminent phase transition during disease progression.
Bioinform., 2020

Quantifying Waddington's epigenetic landscape: a comparison of single-cell potency measures.
Briefings Bioinform., 2020

Network control principles for identifying personalized driver genes in cancer.
Briefings Bioinform., 2020

Identification of Alzheimer's disease based on wavelet transformation energy feature of the structural MRI image and NN classifier.
Artif. Intell. Medicine, 2020

CIDO: The Community-Based Coronavirus Infectious Disease Ontology.
Proceedings of the 11th International Conference on Biomedical Ontologies (ICBO) joint with the 10th Workshop on Ontologies and Data in Life Sciences (ODLS) and part of the Bolzano Summer of Knowledge (BoSK 2020), 2020

Efficient Mining Closed k-Mers from DNA and Protein Sequences.
Proceedings of the 2020 IEEE International Conference on Big Data and Smart Computing, 2020

Network biomarker for quantifying regular state of a biological system, and dynamic network biomarker for quantifying critical state of a biological system.
Proceedings of the IEEE International Conference on Bioinformatics and Biomedicine, 2020

2019
A Semisupervised Classification Approach for Multidomain Networks With Domain Selection.
IEEE Trans. Neural Networks Learn. Syst., 2019

Associating lncRNAs with small molecules via bilevel optimization reveals cancer-related lncRNAs.
PLoS Comput. Biol., 2019

Quantifying pluripotency landscape of cell differentiation from scRNA-seq data by continuous birth-death process.
PLoS Comput. Biol., 2019

A novel network control model for identifying personalized driver genes in cancer.
PLoS Comput. Biol., 2019

Victors: a web-based knowledge base of virulence factors in human and animal pathogens.
Nucleic Acids Res., 2019

Systems biology intertwines with single cell and AI.
BMC Bioinform., 2019

2018
Integrating data- and model-driven strategies in systems biology.
BMC Syst. Biol., 2018

Improved flower pollination algorithm for identifying essential proteins.
BMC Syst. Biol., 2018

Single cell clustering based on cell-pair differentiability correlation and variance analysis.
Bioinform., 2018

Discovering personalized driver mutation profiles of single samples in cancer by network control strategy.
Bioinform., 2018

2017
Quantifying critical states of complex diseases using single-sample dynamic network biomarkers.
PLoS Comput. Biol., 2017

Differential function analysis: identifying structure and activation variations in dysregulated pathways.
Sci. China Inf. Sci., 2017

Detecting causality from short time-series data based on prediction of topologically equivalent attractors.
BMC Syst. Biol., 2017

Understanding biological systems through the lens of data.
BMC Syst. Biol., 2017

Comparative network stratification analysis for identifying functional interpretable network biomarkers.
BMC Bioinform., 2017

Pattern fusion analysis by adaptive alignment of multiple heterogeneous omics data.
Bioinform., 2017

Mining K-mers of Various Lengths in Biological Sequences.
Proceedings of the Bioinformatics Research and Applications - 13th International Symposium, 2017

2016
Inference of Gene Regulatory Network Based on Local Bayesian Networks.
PLoS Comput. Biol., 2016

CMIP: a software package capable of reconstructing genome-wide regulatory networks using gene expression data.
BMC Bioinform., 2016

Detecting critical state before phase transition of complex biological systems by hidden Markov model.
Bioinform., 2016

Big-data-based edge biomarkers: study on dynamical drug sensitivity and resistance in individuals.
Briefings Bioinform., 2016

Integration of multiple heterogeneous omics data.
Proceedings of the IEEE International Conference on Bioinformatics and Biomedicine, 2016

2015
Guest Editorial for Special Section on ISB/TBC 2014.
IEEE ACM Trans. Comput. Biol. Bioinform., 2015

Inferring Sequential Order of Somatic Mutations during Tumorgenesis based on Markov Chain Model.
IEEE ACM Trans. Comput. Biol. Bioinform., 2015

Dynamics of an HBV Model with Drug Resistance Under Intermittent Antiviral Therapy.
Int. J. Bifurc. Chaos, 2015

Identifying overlapping communities in social networks using multi-scale local information expansion.
CoRR, 2015

Measuring robustness of community structure in complex networks.
CoRR, 2015

Identifying module biomarker in type 2 diabetes mellitus by discriminative area of functional activity.
BMC Bioinform., 2015

Systematic computation with functional gene-sets among leukemic and hematopoietic stem cells reveals a favorable prognostic signature for acute myeloid leukemia.
BMC Bioinform., 2015

Identifying cancer-related microRNAs based on gene expression data.
Bioinform., 2015

Clustered model reduction of positive directed networks.
Autom., 2015

Identification of phenotypic networks based on whole transcriptome by comparative network decomposition.
Proceedings of the 2015 IEEE International Conference on Bioinformatics and Biomedicine, 2015

2014
The Dynamics of DNA Methylation Covariation Patterns in Carcinogenesis.
PLoS Comput. Biol., 2014

Predicting Time Series from Short-Term High-Dimensional Data.
Int. J. Bifurc. Chaos, 2014

Big Biological Data: Challenges and Opportunities.
Genom. Proteom. Bioinform., 2014

Prediction and early diagnosis of complex diseases by edge-network.
Bioinform., 2014

Identifying critical transitions of complex diseases based on a single sample.
Bioinform., 2014

Detecting tissue-specific early warning signals for complex diseases based on dynamical network biomarkers: study of type 2 diabetes by cross-tissue analysis.
Briefings Bioinform., 2014

Detecting Phosphorylation Determined Active Protein Interaction Network during Cancer Development by Robust Network Component Analysis.
Proceedings of the ACM 8th International Workshop on Data and Text Mining in Bioinformatics, 2014

DTMBIO 2014: International Workshop on Data and Text Mining in Biomedical Informatics.
Proceedings of the 23rd ACM International Conference on Conference on Information and Knowledge Management, 2014

2013
Dynamical network biomarkers for identifying critical transitions and their driving networks of biologic processes.
Quant. Biol., 2013

Research and applications: An integrated approach to identify causal network modules of complex diseases with application to colorectal cancer.
J. Am. Medical Informatics Assoc., 2013

Investigation of anti-cancer mechanisms by comparative analysis of naked mole rat and rat.
BMC Syst. Biol., 2013

Computational systems biology in the big data era.
BMC Syst. Biol., 2013

NOA: a cytoscape plugin for network ontology analysis.
Bioinform., 2013

NARROMI: a noise and redundancy reduction technique improves accuracy of gene regulatory network inference.
Bioinform., 2013

<i>eFG</i>: an electronic resource for <i>Fusarium graminearum</i>.
Database J. Biol. Databases Curation, 2013

Identifying Critical Transitions of Biological Processes by Dynamical Network Biomarkers.
Proceedings of the Bioinformatics Research and Applications, 9th International Symposium, 2013

2012
Guest Editorial: Bioinformatics and Computational Systems Biology.
IEEE ACM Trans. Comput. Biol. Bioinform., 2012

Identifying disease genes and module biomarkers by differential interactions.
J. Am. Medical Informatics Assoc., 2012

Correction: Tracing dynamic biological processes during phase transition.
BMC Syst. Biol., 2012

Tracing dynamic biological processes during phase transition.
BMC Syst. Biol., 2012

Modelling biological systems from molecules to dynamical networks.
BMC Syst. Biol., 2012

A computational procedure for identifying master regulator candidates: a case study on diabetes progression in Goto-Kakizaki rats.
BMC Syst. Biol., 2012

Rational drug repositioning guided by an integrated pharmacological network of protein, disease and drug.
BMC Syst. Biol., 2012

Inferring a protein interaction map of Mycobacterium tuberculosis based on sequences and interologs.
BMC Bioinform., 2012

Identifying dysregulated pathways in cancers from pathway interaction networks.
BMC Bioinform., 2012

Inferring gene regulatory networks from gene expression data by path consistency algorithm based on conditional mutual information.
Bioinform., 2012

Network clustering along diabetes progression in three tissues of Goto-Kakizaki rats.
Proceedings of the 6th IEEE International Conference on Systems Biology, 2012

A fixed-point blind source extraction algorithm and its application to ECG data analysis.
Proceedings of the 6th IEEE International Conference on Systems Biology, 2012

Module network rewiring in response to therapy.
Proceedings of the 6th IEEE International Conference on Systems Biology, 2012

in silico identification of novel cancer-related genes by comparative genomics of naked mole rat and rat.
Proceedings of the 6th IEEE International Conference on Systems Biology, 2012

A new method to identify repositioned drugs for prostate cancer.
Proceedings of the 6th IEEE International Conference on Systems Biology, 2012

Construction and analysis of genome-wide SNP networks.
Proceedings of the 6th IEEE International Conference on Systems Biology, 2012

A Gaussian graphical model for identifying significantly responsive regulatory networks from time series gene expression data.
Proceedings of the 6th IEEE International Conference on Systems Biology, 2012

Comparative analysis of protein-coding genes and long non-coding RNAs of prostate cancer between Caucasian and Chinese populations.
Proceedings of the 6th IEEE International Conference on Systems Biology, 2012

Clustering-based ℌ2-state aggregation of positive networks and its application to reduction of chemical master equations.
Proceedings of the 51th IEEE Conference on Decision and Control, 2012

Reconstructing dynamic gene regulatory network for the development process of hepatocellular carcinoma.
Proceedings of the 2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops, 2012

Dynamical modeling of chronic myeloid leukemia progression and the development of mutations.
Proceedings of the 2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops, 2012

2011
Network screening of Goto-Kakizaki rat liver microarray data during diabetic progression.
BMC Syst. Biol., 2011

Computational systems biology: integration of sequence, structure, network, and dynamics.
BMC Syst. Biol., 2011

Multi-equilibrium property of metabolic networks: SSI module.
BMC Syst. Biol., 2011

Neural fate decisions mediated by <i>trans</i>-activation and <i>cis</i>-inhibition in Notch signaling.
Bioinform., 2011

Inferring Protein-Protein Interactions Based on Sequences and Interologs in Mycobacterium Tuberculosis.
Proceedings of the Bio-Inspired Computing and Applications, 2011

2010
The effect of coupled feedback on noise filtering in signal transduction networks.
J. Syst. Sci. Complex., 2010

Self-organizing map of complex networks for community detection.
J. Syst. Sci. Complex., 2010

Editorial.
J. Syst. Sci. Complex., 2010

A systems biology approach to identify effective cocktail drugs.
BMC Syst. Biol., 2010

Optimization meets systems biology.
BMC Syst. Biol., 2010

FGsub: Fusarium graminearum protein subcellular localizations predicted from primary structures.
BMC Syst. Biol., 2010

Identifying dysfunctional crosstalk of pathways in various regions of Alzheimer's disease brains.
BMC Syst. Biol., 2010

Detecting disease associated modules and prioritizing active genes based on high throughput data.
BMC Bioinform., 2010

Prediction of protein-RNA binding sites by a random forest method with combined features.
Bioinform., 2010

Inferring gene regulatory networks from expression data with prior knowledge by linear programming.
Proceedings of the International Conference on Machine Learning and Cybernetics, 2010

Bioinformatics Methods for Protein Identification Using Peptide Mass Fingerprinting.
Proceedings of the Proteome Bioinformatics, 2010

2009
Fuzzy System Methods in Modeling Gene Expression and Analyzing Protein Networks.
Proceedings of the Fuzzy Systems in Bioinformatics and Computational Biology, 2009

Evaluating Protein Similarity from Coarse Structures.
IEEE ACM Trans. Comput. Biol. Bioinform., 2009

Disease-Aging Network Reveals Significant Roles of Aging Genes in Connecting Genetic Diseases.
PLoS Comput. Biol., 2009

Self-organizing map approaches for the haplotype assembly problem.
Math. Comput. Simul., 2009

Automatic Modeling of Signaling Pathways by Network Flow Model.
J. Bioinform. Comput. Biol., 2009

Robustness of interval gene networks with multiple time-varying delays and noise.
Neurocomputing, 2009

Modeling post-transcriptional regulation activity of small non-coding RNAs in <i>Escherichia coli</i>.
BMC Bioinform., 2009

Dynamically dysfunctional protein interactions in the development of Alzheimer's disease.
Proceedings of the IEEE International Conference on Systems, 2009

Analysis and Optimality on Network Traffic Flows.
Proceedings of the CSIE 2009, 2009 WRI World Congress on Computer Science and Information Engineering, March 31, 2009

Multiple Phase Transitions in the Culture Dissemination.
Proceedings of the Complex Sciences, 2009

Analysis on steady states of photosynthetic carbon metabolic system.
Proceedings of the 48th IEEE Conference on Decision and Control, 2009

A New Balanced Ensemble Classifier for Predicting Fungi Protein Subcellular Localization Based on Protein Primary Structures.
Proceedings of the 2nd International Conference on BioMedical Engineering and Informatics, 2009

2008
Modeling and Analyzing Biological Oscillations in Molecular Networks.
Proc. IEEE, 2008

Clustering complex networks and biological networks by nonnegative matrix factorization with various similarity measures.
Neurocomputing, 2008

Associative memory with a controlled chaotic neural network.
Neurocomputing, 2008

Protein function prediction with the shortest path in functional linkage graph and boosting.
Int. J. Bioinform. Res. Appl., 2008

Protein cavity clustering based on community structure of pocket similarity network.
Int. J. Bioinform. Res. Appl., 2008

Biomolecular network querying: a promising approach in systems biology.
BMC Syst. Biol., 2008

Gene function prediction using labeled and unlabeled data.
BMC Bioinform., 2008

Domain-Domain Interaction Identification with a Feature Selection Approach.
Proceedings of the Pattern Recognition in Bioinformatics, 2008

A Novel Classifier Based on Enhanced Lipschitz Embedding for Speech Emotion Recognition.
Proceedings of the Advanced Intelligent Computing Theories and Applications. With Aspects of Theoretical and Methodological Issues, 2008

Reconstruction of Regulator Activity in E. coli Post-Transcription Processes.
Proceedings of the 2008 IEEE International Conference on Bioinformatics and Biomedicine, 2008

Automatic Modeling of Signal Pathways from Protein-Protein Interaction Networks.
Proceedings of the 6th Asia-Pacific Bioinformatics Conference, 2008

2007
Stochastic Stability of Genetic Networks With Disturbance Attenuation.
IEEE Trans. Circuits Syst. II Express Briefs, 2007

A Systems Biology Perspective on Signal Processing in Genetic Network Motifs [Life Sciences].
IEEE Signal Process. Mag., 2007

Supervised classification of protein structures based on convex hull representation.
Int. J. Bioinform. Res. Appl., 2007

Stochastic synchronization of genetic oscillator networks.
BMC Syst. Biol., 2007

Analysis on multi-domain cooperation for predicting protein-protein interactions.
BMC Bioinform., 2007

Predicting gene ontology functions from protein's regional surface structures.
BMC Bioinform., 2007

Inferring transcriptional regulatory networks from high-throughput data.
Bioinform., 2007

Alignment of molecular networks by integer quadratic programming.
Bioinform., 2007

Detecting Community Structure in Complex Networks by Optimal Rearrangement Clustering.
Proceedings of the Emerging Technologies in Knowledge Discovery and Data Mining, 2007

Frequency Synchronization of a Set of Cells Coupled by Quorum Sensing.
Proceedings of the Life System Modeling and Simulation, International Conference, 2007

Identifying Modules in Complex Networks by a Graph-Theoretical Method and Its Application in Protein Interaction Networks.
Proceedings of the Advanced Intelligent Computing Theories and Applications. With Aspects of Artificial Intelligence, 2007

Double Three-Level Inverter Based Variable Frequency Drive with Minimal Total Harmonic Distortion Using Particle Swarm Optimization.
Proceedings of the Advanced Intelligent Computing Theories and Applications. With Aspects of Theoretical and Methodological Issues, 2007

2006
Stability of Genetic Networks With SUM Regulatory Logic: Lur'e System and LMI Approach.
IEEE Trans. Circuits Syst. I Regul. Pap., 2006

Designing Gene Regulatory Networks With Specified Functions.
IEEE Trans. Circuits Syst. I Regul. Pap., 2006

Transient Resetting: A Novel Mechanism for Synchrony and Its Biological Examples.
PLoS Comput. Biol., 2006

Inferring gene regulatory networks from multiple microarray datasets.
Bioinform., 2006

Synchronizing a multicellular system by external input: an artificial control strategy.
Bioinform., 2006

Automatic Classification of Protein Structures Based on Convex Hull Representation by Integrated Neural Network.
Proceedings of the Theory and Applications of Models of Computation, 2006

Designing synthetic biological networks.
Proceedings of the International Symposium on Circuits and Systems (ISCAS 2006), 2006

Forecasting Electricity Demand by Hybrid Machine Learning Model.
Proceedings of the Neural Information Processing, 13th International Conference, 2006

Supervised Inference of Gene Regulatory Networks by Linear Programming.
Proceedings of the Computational Intelligence and Bioinformatics, 2006

Design and Implementation of Probability-Based Scoring Function for Peptide Mass Fingerprinting Protein Identification.
Proceedings of the 28th International Conference of the IEEE Engineering in Medicine and Biology Society, 2006

Alignment of Protein Interaction Networks by Integer Quadratic Programming.
Proceedings of the 28th International Conference of the IEEE Engineering in Medicine and Biology Society, 2006

2005
Aligning Multiple Protein Structures by Deterministic Annealing.
J. Bioinform. Comput. Biol., 2005

Exploring Protein's Optimal Hp Configurations by Self-organizing Mapping.
J. Bioinform. Comput. Biol., 2005

A parsimonious tree-grow method for haplotype inference.
Bioinform., 2005

Protein structure alignment by deterministic annealing.
Bioinform., 2005

Noise-induced cooperative behavior in a multicell system.
Bioinform., 2005

Peak Load Forecasting Using the Self-organizing Map.
Proceedings of the Advances in Neural Networks - ISNN 2005, Second International Symposium on Neural Networks, Chongqing, China, May 30, 2005

Cooperative dynamics coordinated by stochastic noise in a multi-cell system.
Proceedings of the International Symposium on Circuits and Systems (ISCAS 2005), 2005

Reducing Gene Regulatory Networks by Decomposition.
Proceedings of the Fourth International IEEE Computer Society Computational Systems Bioinformatics Conference Workshops & Poster Abstracts, 2005

2004
Designing Synthetic Biological Systems by Multiple Time Scale Networks.
Proceedings of the 3rd International IEEE Computer Society Computational Systems Bioinformatics Conference, 2004

2003
Uniform asymptotic stability of hybrid dynamical systems with delay.
IEEE Trans. Autom. Control., 2003

Multiple Protein Structure Alignment by Deterministic Annealing.
Proceedings of the 2nd IEEE Computer Society Bioinformatics Conference, 2003

2002
Design of Genetic Switches with Only Positive Feedback Loops.
Proceedings of the 1st IEEE Computer Society Bioinformatics Conference, 2002

Designing Oscillators in Synthetic Gene Networks Based on Multi-Scale Dynamics.
Proceedings of the 1st IEEE Computer Society Bioinformatics Conference, 2002

1998
Bifurcation analysis of hybrid dynamical systems.
Proceedings of the IEEE International Conference on Systems, Man and Cybernetics, 1998

1995
Chaotic simulated annealing by a neural network model with transient chaos.
Neural Networks, 1995

An application of mean field theory to optimal power flow.
Proceedings of International Conference on Neural Networks (ICNN'95), Perth, WA, Australia, November 27, 1995


  Loading...