Leszek Konieczny

According to our database, Leszek Konieczny authored at least 52 papers between 1995 and 2024.

Collaborative distances:

• Dijkstra number of five.
• Erdős number of four.

2024

The outer-membrane componentof the multi-drug efflux system -a structural analysis based onhydrophobicity distribution.

Irena Roterman, Leszek Konieczny, Katarzyna Stapor

Bio Algorithms Med Syst., 2024

2023

Role of environmental specificity in CASP results.

Irena Roterman, Katarzyna Stapor, Leszek Konieczny

BMC Bioinform., December, 2023

Ab initio protein structure prediction: the necessary presence of external force field as it is delivered by Hsp40 chaperone.

Irena Roterman, Katarzyna Stapor, Leszek Konieczny

BMC Bioinform., December, 2023

Protein Is an Intelligent Micelle.

Irena Roterman, Leszek Konieczny

Entropy, June, 2023

2021

Divergence Entropy-Based Evaluation of Hydrophobic Core in Aggressive and Resistant Forms of Transthyretin.

Mateusz Banach, Katarzyna Stapor, Piotr Fabian, Leszek Konieczny, Irena Roterman

Entropy, 2021

2020

Alternative Hydrophobic Core in Proteins - The Effect of Specific Synergy.

Piotr Fabian, Katarzyna Stapor, Mateusz Banach, Magdalena Ptak-Kaczor, Leszek Konieczny, Irena Roterman

Symmetry, 2020

The Status of Edge Strands in Ferredoxin-Like Fold.

Mateusz Banach, Piotr Fabian, Katarzyna Stapor, Leszek Konieczny, Magdalena Ptak-Kaczor, Irena Roterman

Symmetry, 2020

System to simulate the activity of living organism - construction of proteome.

Krzysztof Mikuta, Leszek Konieczny, Irena Roterman

J. Comput. Sci., 2020

Protein folding vs. COVID-19 and the Mediterranean diet.

Irena Roterman, Leszek Konieczny

Bio Algorithms Med Syst., 2020

2019

Symmetry and Dissymmetry in Protein Structure - System-Coding Its Biological Specificity.

Mateusz Banach, Leszek Konieczny, Irena Roterman

Symmetry, 2019

Structural analysis of the Aβ(11-42) amyloid fibril based on hydrophobicity distribution.

Irena Roterman, Dawid Dulak, Malgorzata Gadzala, Mateusz Banach, Leszek Konieczny

J. Comput. Aided Mol. Des., 2019

The living organism: evolutionary design or an accident.

Irena Roterman, Leszek Konieczny

Bio Algorithms Med Syst., 2019

Personalized precision medicine.

Leszek Konieczny, Irena Roterman

Bio Algorithms Med Syst., 2019

2018

Comparison of the structure of Aβ(1-40) amyloid with the one in complex with polyphenol ε-viniferin glucoside (EVG).

Dawid Dulak, Mateusz Banach, Zdzislaw Wisniowski, Leszek Konieczny, Irena Roterman

Bio Algorithms Med Syst., 2018

Chromatin 3D - will it make understanding of cancer transformation finally possible?

Grazyna Drabik, Jolanta Kaszuba-Zwoinska, Zdzislaw Wisniowski, Leszek Konieczny, Irena Roterman

Bio Algorithms Med Syst., 2018

Fragment Aβ(18-41) presented within the CDR3 loop region of a shark immunoglobulin new antigen receptor single-variable domain antibody analyzed based on the fuzzy oil drop model.

Mateusz Banach, Leszek Konieczny, Zdzislaw Wisniowski, Irena Roterman

Bio Algorithms Med Syst., 2018

2017

Application of the Fuzzy Oil Drop Model Describes Amyloid as a Ribbonlike Micelle.

Irena Roterman, Mateusz Banach, Leszek Konieczny

Entropy, 2017

Chain-chain complexation and heme binding in haemoglobin with respect to the hydrophobic core structure.

Magdalena Ptak, Mateusz Banach, Zdzislaw Wisniowski, Leszek Konieczny, Irena Roterman

Bio Algorithms Med Syst., 2017

Role of the hydrophobic core in cytoskeleton protein: cardiac myosin binding protein C.

Maria Golda, Mateusz Banach, Zdzislaw Wisniowski, Wojciech Ziajka, Leszek Konieczny, Irena Roterman

Bio Algorithms Med Syst., 2017

Mechanism of ligand binding - PDZ domain taken as example.

Dawid Dulak, Mateusz Banach, Zdzislaw Wisniowski, Leszek Konieczny, Irena Roterman

Bio Algorithms Med Syst., 2017

The variability of protein structure with respect to the hydrophobic core.

Mateusz Banach, Zdzislaw Wisniowski, Barbara Kalinowska, Leszek Konieczny, Irena Roterman

Bio Algorithms Med Syst., 2017

Structure of hydrophobic core in plant carboxylesterase.

Mateusz Banach, Leszek Konieczny, Zdzislaw Wisniowski, Irena Roterman

Bio Algorithms Med Syst., 2017

2016

Influence of the Aqueous Environment on Protein Structure - A Plausible Hypothesis Concerning the Mechanism of Amyloidogenesis.

Irena Roterman, Mateusz Banach, Barbara Kalinowska, Leszek Konieczny

Entropy, 2016

Role of Disulfide Bonds in Stabilizing the Conformation of Selected Enzymes - An Approach Based on Divergence Entropy Applied to the Structure of Hydrophobic Core in Proteins.

Mateusz Banach, Barbara Kalinowska, Leszek Konieczny, Irena Roterman

Entropy, 2016

Dissimilar sequence: similar structure of proteins.

Mateusz Banach, Leszek Konieczny, Irena Roterman

Bio Algorithms Med Syst., 2016

2015

Application of Divergence Entropy to Characterize the Structure of the Hydrophobic Core in DNA Interacting Proteins.

Barbara Kalinowska, Mateusz Banach, Leszek Konieczny, Irena Roterman

Entropy, 2015

Hydrophobic core structure of macromomycin - the apoprotein of the antitumor antibiotic auromomycin - fuzzy oil drop model applied.

Irena Roterman-Konieczna, Mateusz Banach, Leszek Konieczny

Bio Algorithms Med Syst., 2015

The use of Titan yellow dye as a metal ion binding marker for studies on the formation of specific complexes by supramolecular Congo red.

Katarzyna Chlopas, Anna Jagusiak, Leszek Konieczny, Barbara Piekarska, Irena Roterman, Janina Rybarska, Barbara Stopa, Grzegorz Zemanek, Elzbieta Bielanska, Piotr Piwowar, Krystyna Sadlik

Bio Algorithms Med Syst., 2015

2014

Attempt at a systemic outlook on aging and carcinogenesis.

Monika Piwowar, Jacek Dygut, Piotr Piwowar, Leszek Konieczny, Irena Roterman

Bio Algorithms Med Syst., 2014

2013

Structural role of exon-coded fragments in proteins.

Monika Piwowar, Mateusz Banach, Leszek Konieczny, Irena Roterman

Bio Algorithms Med Syst., 2013

Structural role of exons in hemoglobin.

Monika Piwowar, Mateusz Banach, Leszek Konieczny, Jacques Chomilier, Irena Roterman

Bio Algorithms Med Syst., 2013

2012

BIOLOGICAL CLOCK - Is the Need for a Clock a Common Issue for Cells and Computers?

Pawel Spólnik, Leszek Konieczny, Irena Roterman, Michal Markiewicz

Bio Algorithms Med Syst., 2012

Technical Solutions for Bio-Measurements.

Leszek Konieczny, Michal Markiewicz, Piotr Piwowar, Irena Roterman

Bio Algorithms Med Syst., 2012

Stability of Two Natural Homologous Proteins with Different Folds.

Leszek Konieczny, Mateusz Banach, Irena Roterman

Bio Algorithms Med Syst., 2012

2011

The criteria of life and aging from a molecular viewpoint. The role of protein aggregation in the process of aging.

Pawel Spólnik, Leszek Konieczny, Barbara Piekarska, Janina Rybarska, Barbara Stopa, Grzegorz Zemanek

Bio Algorithms Med Syst., 2011

2010

The criterion of biological life in the developing robot era.

Pawel Spólnik, Leszek Konieczny

Bio Algorithms Med Syst., 2010

2007

Prediction of Functional Sites Based on the Fuzzy Oil Drop Model.

Michal Brylinski, Katarzyna Prymula, Wiktor Jurkowski, Marek Kochanczyk, Ewa Stawowczyk, Leszek Konieczny, Irena Roterman

PLoS Comput. Biol., 2007

Is the protein folding an aim-oriented process? Human haemoglobin as example.

Michal Brylinski, Leszek Konieczny, Irena Roterman

Int. J. Bioinform. Res. Appl., 2007

2006

Gauss-Function-Based Model of Hydrophobicity Density in Proteins.

Leszek Konieczny, Michal Brylinski, Irena Roterman

Silico Biol., 2006

Sequence-Structure-Function Relation Characterized in silico.

Michal Brylinski, Marek Kochanczyk, Leszek Konieczny, Irena Roterman

Silico Biol., 2006

Hydrophobic collapse in (<i>in silico</i>) protein folding.

Michal Brylinski, Leszek Konieczny, Irena Roterman

Comput. Biol. Chem., 2006

Protein complexes with supramolecular ligands formed and revealed in two-dimensional electrophoresis. The search for computer analysis of results.

Joanna Rybarska, Pawel Spólnik, Anna Drozd, Leszek Konieczny, Barbara Piekarska, Barbara Stopa, Grzegorz Zemanek, Marcin Król, Irena Roterman-Konieczna

Bio Algorithms Med Syst., 2006

Specific supramolecular ligands with proteins. Possible practical application.

Joanna Grabska-Chrzastowska, Anna Drozd, Leszek Konieczny, Janina Rybarska, Barbara Stopa, Barbara Piekarska, Irena Roterman, Marcin Król, Pawel Spólnik, Grzegorz Zemanek

Bio Algorithms Med Syst., 2006

How specially adapted chromatographic bed material might be used for the controlled formation of immune complexes and studies of congo red binding to bivalent antibodies.

Anna Drozd, Leszek Konieczny, Barbara Piekarska, Janina Rybarska, Barbara Stopa, Grzegorz Zemanek

Bio Algorithms Med Syst., 2006

2004

Force-field parametrization and molecular dynamics simulations of Congo red.

Marcin Król, Tomasz Borowski, Irena Roterman, Barbara Piekarska, Barbara Stopa, Joanna Rybarska, Leszek Konieczny

J. Comput. Aided Mol. Des., 2004

SPI - Structure predictability index for protein sequences.

Michal Brylinski, Leszek Konieczny, Irena Roterman

Silico Biol., 2004

Limited conformational space for early-stage protein folding simulation.

Michal Brylinski, Wiktor Jurkowski, Leszek Konieczny, Irena Roterman

Bioinform., 2004

2003

Search for structural similarity in proteins.

Jacek Leluk, Leszek Konieczny, Irena Roterman

Bioinform., 2003

2000

Why do Congo Red, Evans Blue, and Trypan Blue differ in their complexation properties?

Marek Skowronek, Irena Roterman, Leszek Konieczny, Barbara Stopa, Janina Rybarska, Barbara Piekarska

J. Comput. Chem., 2000

The Conformational Characteristics of Congo Red, Evans Blue and Trypan Blue.

Marek Skowronek, Irena Roterman, Leszek Konieczny, Barbara Stopa, Janina Rybarska, Barbara Piekarska, Andrzej Górecki, Marek Król

Comput. Chem., 2000

1998

Congo Red Bound to -1-Proteinase Inhibitor As a Model of Supramolecular Ligand and Protein Complex.

Irena Roterman, Janina Rybarska, Leszek Konieczny, Marek Skowronek, Barbara Stopa, Barbara Piekarska, Grzegorz Bakalarski

Comput. Chem., 1998

1995

Geometrical Analysis of Structural Changes in Immunoglobulin Domains' Transition From Native to Molten State.

Irena Roterman, Leszek Konieczny

Comput. Chem., 1995