Hirokazu Sugiyama

According to our database, Hirokazu Sugiyama authored at least 20 papers between 2014 and 2024.

Collaborative distances:

• Dijkstra number of five.
• Erdős number of four.

2024

Data-driven parameterization and development of mechanistic cell cultivation models in monoclonal antibody production processes: Shifts in cell metabolic behavior.

Kozue Okamura, Kota Oishi, Sara Badr, Akira Yamada, Hirokazu Sugiyama

Comput. Chem. Eng., 2024

2023

The role of process systems engineering in applying quality by design (QbD) in mesenchymal stem cell production.

Isuru A. Udugama, Sara Badr, Keita Hirono, Benedikt X. Scholz, Yusuke Hayashi, Masahiro Kino-oka, Hirokazu Sugiyama

Comput. Chem. Eng., April, 2023

A CFD model-based design of seeding processes for two-dimensional mesenchymal stem cell cultivation.

Benedikt X. Scholz, Yusuke Hayashi, Isuru A. Udugama, Masahiro Kino-oka, Hirokazu Sugiyama

Comput. Chem. Eng., March, 2023

Surrogate modeling of dissolution behavior toward efficient design of tablet manufacturing processes.

Kensaku Matsunami, Tomohiro Miura, Keita Yaginuma, Shuichi Tanabe, Sara Badr, Hirokazu Sugiyama

Comput. Chem. Eng., March, 2023

Agile process systems engineering education: What to teach, and how to teach.

Daniel R. Lewin, Emilia M. Kondili, Ian T. Cameron, Grégoire Léonard, Seyed Soheil Mansouri, Fernando Gomes Martins, Luis A. Ricardez-Sandoval, Hirokazu Sugiyama, Edwin Zondervan

Comput. Chem. Eng., February, 2023

2022

A multilayered approach to scale-up forced convection-based freezing of human induced pluripotent stem cells.

Benedikt X. Scholz, Yusuke Hayashi, Isuru A. Udugama, Masahiro Kino-oka, Hirokazu Sugiyama

Comput. Chem. Eng., 2022

Model-based comparison of batch and flow syntheses of an active pharmaceutical ingredient using heterogeneous hydrogenation.

Junu Kim, Hironori Yonekura, Takeaki Watanabe, Satoshi Yoshikawa, Hayao Nakanishi, Sara Badr, Hirokazu Sugiyama

Comput. Chem. Eng., 2022

Hybrid-model-based design of fill-freeze-thaw processes for human induced pluripotent stem cells considering productivity and quality.

Yusuke Hayashi, Masahiro Kino-oka, Hirokazu Sugiyama

Comput. Chem. Eng., 2022

2021

Model-based assessment of temperature profiles in slow freezing for human induced pluripotent stem cells.

Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Hirokazu Sugiyama

Comput. Chem. Eng., 2021

Integrated design of biopharmaceutical manufacturing processes: Operation modes and process configurations for monoclonal antibody production.

Sara Badr, Kozue Okamura, Nozomi Takahashi, Vera Ubbenjans, Haruku Shirahata, Hirokazu Sugiyama

Comput. Chem. Eng., 2021

2020

Slow freezing process design for human induced pluripotent stem cells by modeling intracontainer variation.

Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, Hirokazu Sugiyama

Comput. Chem. Eng., 2020

2019

Multiobjective decision-support tools for the choice between single-use and multi-use technologies in sterile filling of biopharmaceuticals.

Haruku Shirahata, Masahiko Hirao, Hirokazu Sugiyama

Comput. Chem. Eng., 2019

Alternative generation and multiobjective evaluation using a design framework: Case study on sterile filling processes of biopharmaceuticals.

Haruku Shirahata, Sara Badr, Shant Dakessian, Hirokazu Sugiyama

Comput. Chem. Eng., 2019

Data mining algorithm for pre-processing biopharmaceutical drug product manufacturing records.

Gioele Casola, Christian Siegmund, Markus Mattern, Hirokazu Sugiyama

Comput. Chem. Eng., 2019

Lasing Characteristics of GalnAsP SCH MQW High-mesa Laser on Silicon Substrate.

Koki Tsushima, Kazuki Uchida, Xu Han, Hirokazu Sugiyama, Masaki Aikawa, Natsuki Hayasaka, Masaki Matsuura, Takahiro Ishizaki, Takuto Shirai, Kazuhiko Shimomura

Proceedings of the 2019 24th OptoElectronics and Communications Conference (OECC) and 2019 International Conference on Photonics in Switching and Computing (PSC), 2019

Lasing characteristics of GalnAsP SCH-MQW Laser Diode on Directly-bonded InP/Si Substrate.

Takahiro Ishizaki, Kazuki Uchida, Hirokazu Sugiyama, Xu Han, Natsuki Hayasaka, Masaki Aikawa, Masaki Matsuura, Koki Tsushima, Takuto Shirai, Kazuhiko Shimomura

Proceedings of the 2019 24th OptoElectronics and Communications Conference (OECC) and 2019 International Conference on Photonics in Switching and Computing (PSC), 2019

2016

Data-driven tiered procedure for enhancing yield in drug product manufacturing.

Lukas Gallus Eberle, Hirokazu Sugiyama, Stavros Papadokonstantakis, Andreas Graser, Rainer Schmidt, Konrad Hungerbühler

Comput. Chem. Eng., 2016

Rigorous approach to scheduling of sterile drug product manufacturing.

Lukas Gallus Eberle, Elisabet Capón-García, Hirokazu Sugiyama, Andreas Graser, Rainer Schmidt, Konrad Hungerbühler

Comput. Chem. Eng., 2016

2015

Systematic retrofitting methodology for pharmaceutical drug purification processes.

Gioele Casola, Satoshi Yoshikawa, Hayao Nakanishi, Masahiko Hirao, Hirokazu Sugiyama

Comput. Chem. Eng., 2015

2014

Improving lead time of pharmaceutical production processes using Monte Carlo simulation.

Lukas Gallus Eberle, Hirokazu Sugiyama, Rainer Schmidt

Comput. Chem. Eng., 2014