Hans-Peter Lenhof

Orcid: 0000-0002-5820-9961

Affiliations:
  • Saarland University, Center for Bioinformatics, Saarbrücken, Germany


According to our database1, Hans-Peter Lenhof authored at least 80 papers between 1992 and 2024.

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Timeline

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Bibliography

2024
Trust me if you can: a survey on reliability and interpretability of machine learning approaches for drug sensitivity prediction in cancer.
Briefings Bioinform., 2024

A comprehensive benchmarking of machine learning algorithms and dimensionality reduction methods for drug sensitivity prediction.
Briefings Bioinform., 2024

2021
miRTargetLink 2.0 - interactive miRNA target gene and target pathway networks.
Nucleic Acids Res., 2021

MERIDA: a novel Boolean logic-based integer linear program for personalized cancer therapy.
Bioinform., 2021

2020
miRPathDB 2.0: a novel release of the miRNA Pathway Dictionary Database.
Nucleic Acids Res., 2020

GeneTrail 3: advanced high-throughput enrichment analysis.
Nucleic Acids Res., 2020

2019
Machine Learning to Detect Alzheimer's Disease from Circulating Non-coding RNAs.
Genom. Proteom. Bioinform., 2019

ClinOmicsTrailbc: a visual analytics tool for breast cancer treatment stratification.
Bioinform., 2019

2018
miRCarta: a central repository for collecting miRNA candidates.
Nucleic Acids Res., 2018

Genome-wide MicroRNA Expression Profiles in COPD: Early Predictors for Cancer Development.
Genom. Proteom. Bioinform., 2018

REGGAE: a novel approach for the identification of key transcriptional regulators.
Bioinform., 2018

A high-resolution map of the human small non-coding transcriptome.
Bioinform., 2018

2017
RegulatorTrail: a web service for the identification of key transcriptional regulators.
Nucleic Acids Res., 2017

miRPathDB: a new dictionary on microRNAs and target pathways.
Nucleic Acids Res., 2017

Phylogenomics with Paralogs.
CoRR, 2017

2016
EDISON-WMW: Exact Dynamic Programing Solution of the Wilcoxon-Mann-Whitney Test.
Genom. Proteom. Bioinform., 2016

Multi-omics enrichment analysis using the GeneTrail2 web service.
Bioinform., 2016

2015
Network-based interactive navigation and analysis of large biological datasets.
it Inf. Technol., 2015

CausalTrail: Testing hypothesis using causal Bayesian networks.
F1000Research, 2015

ballaxy: web services for structural bioinformatics.
Bioinform., 2015

2014
Efficient computation of root mean square deviations under rigid transformations.
J. Comput. Chem., 2014

2013
NightShift: NMR Shift Inference by General Hybrid Model Training - a Framework for NMR Chemical Shift Prediction.
BMC Bioinform., 2013

NetworkTrail - a web service for identifying and visualizing deregulated subnetworks.
Bioinform., 2013

Efficient Interpretation of Tandem Mass Tags in Top-Down Proteomics.
Proceedings of the German Conference on Bioinformatics 2013, 2013

PresentaBALL - A powerful package for presentations and lessons in structural biology.
Proceedings of the IEEE Symposium on Biological Data Visualization, 2013

2012
miRTrail - a comprehensive webserver for analyzing gene and miRNA patterns to enhance the understanding of regulatory mechanisms in diseases.
BMC Bioinform., 2012

ProteinScanAR - An Augmented Reality Web Application for High School Education in Biomolecular Life Sciences.
Proceedings of the 16th International Conference on Information Visualisation, 2012

2011
Automated bond order assignment as an optimization problem.
Bioinform., 2011

2010
A new Lamarckian genetic algorithm for flexible ligand-receptor docking.
J. Comput. Chem., 2010

Visuelle Analytik biologischer Daten.
Inform. Spektrum, 2010

BALL - biochemical algorithms library 1.3.
BMC Bioinform., 2010

Real-Time Ray Tracing of Complex Molecular Scenes.
Proceedings of the 14th International Conference on Information Visualisation, 2010

Measuring properties of molecular surfaces using ray casting.
Proceedings of the 24th IEEE International Symposium on Parallel and Distributed Processing, 2010

2009
A consensus line search algorithm for molecular potential energy functions.
J. Comput. Chem., 2009

A new method for the gradient-based optimization of molecular complexes.
J. Comput. Chem., 2009

Large-scale antibody profiling of human blood sera: The future of molecular diagnosis.
Inform. Spektrum, 2009

A novel algorithm for detecting differentially regulated paths based on gene set enrichment analysis.
Bioinform., 2009

Automated Bond Order Assignment as an Optimization Problem.
Proceedings of the German Conference on Bioinformatics 2009, 2009

Integer Linear Programming in Computational Biology.
Proceedings of the Efficient Algorithms, 2009

2008
GeneTrailExpress: a web-based pipeline for the statistical evaluation of microarray experiments.
BMC Bioinform., 2008

2007
SePaCS - a web-based application for classification of seroreactivity profiles.
Nucleic Acids Res., 2007

GeneTrail - advanced gene set enrichment analysis.
Nucleic Acids Res., 2007

Abstract analysis of pathways using the BN++ software framework.
BMC Syst. Biol., 2007

BNDB - The Biochemical Network Database.
BMC Bioinform., 2007

Computation of significance scores of unweighted Gene Set Enrichment Analyses.
BMC Bioinform., 2007

Electrostatic potentials of proteins in water: a structured continuum approach.
Bioinform., 2007

2006
A branch-and-cut algorithm for multiple sequence alignment.
Math. Program., 2006

BN++ - A Biological Information System.
J. Integr. Bioinform., 2006

A minimally invasive multiple marker approach allows highly efficient detection of meningioma tumors.
BMC Bioinform., 2006

BALLView: a tool for research and education in molecular modeling.
Bioinform., 2006

2005
GraBCas: a bioinformatics tool for score-based prediction of Caspase- and Granzyme B-cleavage sites in protein sequences.
Nucleic Acids Res., 2005

BALLView: An object-oriented molecular visualization and modeling framework.
J. Comput. Aided Mol. Des., 2005

Glycosylation Patterns of Proteins Studied by Liquid Chromatography-Mass Spectrometry and Bioinformatic Tools.
Proceedings of the Computational Proteomics, 20.-25. November 2005, 2005

2004
Molekulare Bioinformatik.
it Inf. Technol., 2004

2002
A Combinatorial Approach to Protein Docking with Flexible Side Chains.
J. Comput. Biol., 2002

BioMiner - modeling, analyzing, and visualizing biochemical pathways and networks.
Proceedings of the European Conference on Computational Biology (ECCB 2002), 2002

Multiple sequence alignment with arbitrary gap costs: Computing an optimal solution using polyhedral combinatorics.
Proceedings of the European Conference on Computational Biology (ECCB 2002), 2002

2001
A NMR-spectra-based scoring function for protein docking.
Proceedings of the Fifth Annual International Conference on Computational Biology, 2001

2000
Rapid Software Prototyping in Molecular Modeling Using the Biochemical Algorithms Library (BALL).
ACM J. Exp. Algorithmics, 2000

Simulating synthetic polymer chains in parallel.
Future Gener. Comput. Syst., 2000

A polyhedral approach to sequence alignment problems.
Discret. Appl. Math., 2000

BALL-rapid software prototyping in computational molecular biology.
Bioinform., 2000

Workshop "Molekulare Bioinformatik".
Proceedings of the Informatik 2000, 2000

1999
An exact solution for the segment-to-segment multiple sequence alignment problem.
Bioinform., 1999

BALL: Biochemical Algorithms Library.
Proceedings of the Algorithm Engineering, 1999

<i>q</i>-gram based database searching using a suffix array (QUASAR).
Proceedings of the Third Annual International Conference on Research in Computational Molecular Biology, 1999

Rapid Software Prototyping in Computational Molecular Biology.
Proceedings of the German Conference on Bioinformatics, 1999

1998
A Polyhedral Approach to RNA Sequence Structure Alignment.
J. Comput. Biol., 1998

1997
A branch-and-cut algorithm for multiple sequence alignment.
Proceedings of the First Annual International Conference on Research in Computational Molecular Biology, 1997

New contact measures for the protein docking problem.
Proceedings of the First Annual International Conference on Research in Computational Molecular Biology, 1997

Parallel MD-Simulations of Synthetic Polymers.
Proceedings of the Eighth SIAM Conference on Parallel Processing for Scientific Computing, 1997

1995
Static and Dynamic Algorithms for <i>k</i>-Point Clustering Problems.
J. Algorithms, 1995

Sequential and parallel algorithms for the k closest pairs problem.
Int. J. Comput. Geom. Appl., 1995

Maintaining the Visibility Map of Spheres While Moving the Viewpoint on a Circle at Infinity.
Algorithmica, 1995

1994
Using Persistent Data Structures for Adding Range Restrictions to Searching Problems.
RAIRO Theor. Informatics Appl., 1994

An Animation of a Fixed-Radius All-Nearest-Neighbors Algorithm.
Proceedings of the Tenth Annual Symposium on Computational Geometry, 1994

1993
Distanz- und Suchprobleme in der algorithmischen Geometrie und Anwendungen in der Bioinformatik.
PhD thesis, 1993

An optimal construction method for generalized convex layers.
Int. J. Comput. Geom. Appl., 1993

Static and Dynamic Algorithms for k-Point Clustering Problems.
Proceedings of the Algorithms and Data Structures, Third Workshop, 1993

1992
Enumerating the k Closest Pairs Optimally
Proceedings of the 33rd Annual Symposium on Foundations of Computer Science, 1992


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