Glen E. P. Ropella

According to our database, Glen E. P. Ropella authored at least 20 papers between 2004 and 2020.

Collaborative distances:

• Dijkstra number of four.
• Erdős number of three.

2020

Contrasting model mechanisms of alanine aminotransferase (ALT) release from damaged and necrotic hepatocytes as an example of general biomarker mechanisms.

Andrew K. Smith, Glen E. P. Ropella, Mitchell R. McGill, Preethi Krishnan, Lopamudra Dutta, Ryan C. Kennedy, Hartmut Jaeschke, C. Anthony Hunt

PLoS Comput. Biol., 2020

2016

Competing Mechanistic Hypotheses of Acetaminophen-Induced Hepatotoxicity Challenged by Virtual Experiments.

Andrew K. Smith, Brenden K. Petersen, Glen E. P. Ropella, Ryan C. Kennedy, Neil Kaplowitz, Murad Ookhtens, C. Anthony Hunt

PLoS Comput. Biol., 2016

Open-Ended Evolution: Perspectives from the OEE Workshop in York.

Tim Taylor, Mark A. Bedau, Alastair Channon, David H. Ackley, Wolfgang Banzhaf, Guillaume Beslon, Emily L. Dolson, Tom Froese, Simon J. Hickinbotham, Takashi Ikegami, Barry McMullin, Norman H. Packard, Steen Rasmussen, Nathaniel Virgo, Eran Agmon, Edward Clark, Simon McGregor, Charles Ofria, Glen E. P. Ropella, Lee Spector, Kenneth O. Stanley, Adam Stanton, Christopher Steven Timperley, Anya E. Vostinar, Michael J. Wiser

Artif. Life, 2016

Virtual experiments help explain intra- and inter-strain variability of AILI-induced hepatic necrosis in mice.

Andrew K. Smith, Glen E. P. Ropella, C. Anthony Hunt, Neil Kaplowitz, Murad Ookhtens

Proceedings of the Agent-Directed Simulation Symposium, 2016

Measuring analog granularity.

Glen E. P. Ropella, C. Anthony Hunt

Proceedings of the Agent-Directed Simulation Symposium, 2016

Implementing a cell-centered, agent-based framework with flexible environment granularities using MASON and VTK.

Ryan C. Kennedy, Glen E. P. Ropella, C. Anthony Hunt

Proceedings of the Agent-Directed Simulation Symposium, 2016

2014

Toward modular biological models: defining analog modules based on referent physiological mechanisms.

Brenden K. Petersen, Glen E. P. Ropella, C. Anthony Hunt

BMC Syst. Biol., 2014

Mechanistic agent-based damage and repair models as hypotheses for patterns of necrosis caused by drug induced liver injury.

Andrew K. Smith, Glen E. P. Ropella, Neil Kaplowitz, Murad Ookhtens, C. Anthony Hunt

Proceedings of the 2014 Summer Simulation Multiconference, 2014

2012

Falsifying an Enzyme Induction Mechanism within a Validated, Multiscale Liver Model.

Glen E. P. Ropella, Ryan C. Kennedy, C. Anthony Hunt

Int. J. Agent Technol. Syst., 2012

Zonation of drug-induced, hepatic enzyme induction: falsifying fine grained mechanisms within a validated, multiscale In Silico Liver.

Glen E. P. Ropella, C. Anthony Hunt

Proceedings of the 2012 Spring Simulation Multiconference, 2012

2010

Agent-Directed Tracing of Multi-Scale Drug Disposition Events within Normal and Diseased In Silico Livers.

Sean H. J. Kim, Sunwoo Park, Glen E. P. Ropella, C. Anthony Hunt

Int. J. Agent Technol. Syst., 2010

Cloud computing and validation of expandable in silico livers.

Glen E. P. Ropella, C. Anthony Hunt

BMC Syst. Biol., 2010

Agent-based simulation of drug disposition in cirrhotic liver.

Sean H. J. Kim, Sunwoo Park, Glen E. P. Ropella, C. Anthony Hunt

Proceedings of the 2010 Spring Simulation Multiconference, 2010

2009

Evaluating an hepatic enzyme induction mechanism through coarse- and fine-grained measurements of an in silico liver.

Glen E. P. Ropella, Sunwoo Park, C. Anthony Hunt

Complex., 2009

Focus on discovering mechanisms: a relativistic, agent-directed, perfused liver.

Tai Ning Lam, Glen E. P. Ropella, C. Anthony Hunt

Proceedings of the 2009 Spring Simulation Multiconference, SpringSim 2009, 2009

2008

Essential operating principles for tumor spheroid growth.

Jesse Engelberg, Glen E. P. Ropella, C. Anthony Hunt

BMC Syst. Biol., 2008

Predicting hepatic disposition properties of cationic drugs using a physiologically based, agent-oriented In Silico Liver.

Li Yan, Sunwoo Park, Shahab Sheikh-Bahaei, Glen E. P. Ropella, C. Anthony Hunt

Proceedings of the 2008 Spring Simulation Multiconference, 2008

2007

Tracking Compounds and Their Interactions within In Silico Liver.

Sunwoo Park, Sean H. J. Kim, Glen E. P. Ropella, C. Anthony Hunt

Proceedings of the ISCA 20th International Conference on Computer Applications in Industry and Engineering, 2007

Affects of Surface Detection on Shape and Growth of Model Tumor Spheroids.

Jesse Engelberg, Glen E. P. Ropella, C. Anthony Hunt

Proceedings of the ISCA 20th International Conference on Computer Applications in Industry and Engineering, 2007

2004

Biomimetic in Silico Devices.

C. Anthony Hunt, Glen E. P. Ropella, Michael S. Roberts, Li Yan

Proceedings of the Computational Methods in Systems Biology, International Conference, 2004