Gary An

According to our database, Gary An authored at least 24 papers between 2007 and 2024.

Collaborative distances:

• Dijkstra number of four.
• Erdős number of four.

2024

Examining B-cell dynamics and responsiveness in different inflammatory milieus using an agent-based model.

Bryan Shin, Gary An, Chase Cockrell

PLoS Comput. Biol., January, 2024

Toward mechanistic medical digital twins: some use cases in immunology.

Reinhard C. Laubenbacher, Fred Adler, Gary An, Filippo Castiglione, Stephen Eubank, Luis L. Fonseca, James A. Glazier, Tomás Helikar, Marti Jett-Tilton, Denise Kirschner, Paul Macklin, Borna Mehrad, Beth Moore, Virginia Pasour, Ilya Shmulevich, Amber Smith, Isabel Voigt, Thomas E. Yankeelov, Tjalf Ziemssen

Frontiers Digit. Health, 2024

2023

Generating synthetic multi-dimensional molecular-mediator time series data for artificial intelligence-based disease trajectory forecasting and drug development digital twins: Considerations.

Gary An, Chase Cockrell

CoRR, 2023

2022

Building digital twins of the human immune system: toward a roadmap.

Reinhard C. Laubenbacher, Anna Niarakis, Tomás Helikar, Gary An, B. Shapiro, Rahuman S. Malik-Sheriff, T. J. Sego, Adam C. Knapp, Paul Macklin, James A. Glazier

npj Digit. Medicine, 2022

Facilitating automated conversion of scientific knowledge into scientific simulation models with the Machine Assisted Generation, Calibration, and Comparison (MAGCC) Framework.

Chase Cockrell, Scott Christley, Gary An

CoRR, 2022

2021

Nested active learning for efficient model contextualization and parameterization: pathway to generating simulated populations using multi-scale computational models.

Chase Cockrell, Jonathan Ozik, Nick Collier, Gary An

Simul., 2021

2019

Deep Reinforcement Learning and Simulation as a Path Toward Precision Medicine.

Brenden K. Petersen, Jiachen Yang, Will S. Grathwohl, Chase Cockrell, Claudio Santiago, Gary An, Daniel M. Faissol

J. Comput. Biol., 2019

2018

Extreme-Scale Dynamic Exploration of a Distributed Agent-Based Model With the EMEWS Framework.

Jonathan Ozik, Nicholson T. Collier, Justin M. Wozniak, Charles M. Macal, Gary An

IEEE Trans. Comput. Soc. Syst., 2018

Examining the controllability of sepsis using genetic algorithms on an agent-based model of systemic inflammation.

Chase Cockrell, Gary An

PLoS Comput. Biol., 2018

Precision medicine as a control problem: Using simulation and deep reinforcement learning to discover adaptive, personalized multi-cytokine therapy for sepsis.

Brenden K. Petersen, Jiachen Yang, Will S. Grathwohl, Chase Cockrell, Claudio Santiago, Gary An, Daniel M. Faissol

CoRR, 2018

High-throughput cancer hypothesis testing with an integrated PhysiCell-EMEWS workflow.

Jonathan Ozik, Nicholson T. Collier, Justin M. Wozniak, Charles M. Macal, Chase Cockrell, Samuel H. Friedman, Ahmadreza Ghaffarizadeh, Randy W. Heiland, Gary An, Paul Macklin

BMC Bioinform., 2018

2015

A Computational, Tissue-Realistic Model of Pressure Ulcer Formation in Individuals with Spinal Cord Injury.

Cordelia Ziraldo, Alexey Solovyev, Ana Allegretti, Shilpa Krishnan, M. Kristi Henzel, Gwendolyn A. Sowa, David M. Brienza, Gary An, Qi Mi, Yoram Vodovotz

PLoS Comput. Biol., 2015

Computational Studies of the Intestinal Host-Microbiota Interactome.

Scott Christley, Chase Cockrell, Gary An

Comput., 2015

2014

Investigation of Inflammation and Tissue Patterning in the Gut Using a Spatially Explicit General-Purpose Model of Enteric Tissue (SEGMEnT).

Chase Cockrell, Scott Christley, Gary An

PLoS Comput. Biol., 2014

2013

A multiscale modeling approach to inflammation: A case study in human endotoxemia.

Jeremy D. Scheff, Panteleimon D. Mavroudis, Panagiota T. Foteinou, Gary An, Steve E. Calvano, John Doyle, Thomas E. Dick, Stephen F. Lowry, Yoram Vodovotz, Ioannis P. Androulakis

J. Comput. Phys., 2013

Examining the dynamics of epithelial metaplasia and pouchitis in an ileal pouch with a spatially-explicit computational multi-scale gut model (MSGM).

Chase Cockrell, Scott Christley, Gary An, Eugene Chang, Marc Ward

Proceedings of the Agent-Directed Simulation Symposium, 2013

2012

Data-parallel techniques for simulating a mega-scale agent-based model of systemic inflammatory response syndrome on graphics processing units.

Samuel Alberts, Michael K. Keenan, Roshan M. D'Souza, Gary An

Simul., 2012

A proposal for augmenting biological model construction with a semi-intelligent computational modeling assistant.

Scott Christley, Gary An

Comput. Math. Organ. Theory, 2012

2011

A proposed method for dynamic knowledge representation via agent-directed composition from biomedical and simulation ontologies: an example using gut mucus layer dynamics.

Scott Christley, Gary An

Proceedings of the 2011 Spring Simulation Multi-conference, 2011

2010

SPARK: A Framework for Multi-Scale Agent-Based Biomedical Modeling.

Alexey Solovyev, Maxim Mikheev, Leming Zhou, Joyeeta Dutta-Moscato, Cordelia Ziraldo, Gary An, Yoram Vodovotz, Qi Mi

Int. J. Agent Technol. Syst., 2010

Djangology: A Light-weight Web-based Tool for Distributed Collaborative Text Annotation.

Emilia Apostolova, Sean Neilan, Gary An, Noriko Tomuro, Steven L. Lytinen

Proceedings of the International Conference on Language Resources and Evaluation, 2010

2009

Computational disease modeling - fact or fiction?

Jesper Tegnér, Albert Compte, Charles Auffray, Gary An, Gunnar Cedersund, Gilles Clermont, Boris S. Gutkin, Zoltán N. Oltvai, Klaas Enno Stephan, Randy Thomas, Pablo Villoslada

BMC Syst. Biol., 2009

2008

Translational Systems Biology of Inflammation.

Yoram Vodovotz, Márie Csete, John Bartels, Steven Chang, Gary An

PLoS Comput. Biol., 2008

2007

A hybrid simulation model for studying acute inflammatory response.

Wayne W. Wakeland, Louis M. Macovsky, Gary An

Proceedings of the 2007 Spring Simulation Multiconference, 2007