Feng Zhu

Orcid: 0000-0001-8069-0053

Affiliations:
  • Zhejiang University, College of Pharmaceutical Sciences, Hangzhou, China
  • Chongqing University, School of Pharmaceutical Sciences, China (2012 - 2017)
  • National University of Singapore, Department of Pharmacy, Singapore (PhD 2011)


According to our database1, Feng Zhu authored at least 76 papers between 2010 and 2025.

Collaborative distances:
  • Dijkstra number2 of four.
  • Erdős number3 of four.

Timeline

Legend:

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Online presence:

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Bibliography

2025
Expanding the sequence spaces of synthetic binding protein using deep learning-based framework ProteinMPNN.
Frontiers Comput. Sci., May, 2025

2024
RVvictor: Virus RNA-directed molecular interactions for RNA virus infection.
Comput. Biol. Medicine, February, 2024

MoDAFold: a strategy for predicting the structure of missense mutant protein based on AlphaFold2 and molecular dynamics.
Briefings Bioinform., January, 2024

MOINER: A Novel Multiomics Early Integration Framework for Biomedical Classification and Biomarker Discovery.
J. Chem. Inf. Model., 2024

Editorial: Cutting-Edge Methodologies in Omics Data Analysis.
J. Chem. Inf. Model., 2024

Editorial: Machine Learning in Materials Science.
J. Chem. Inf. Model., 2024

Discovery of Potent Selective HDAC6 Inhibitors with 5-Phenyl-1<i>H</i>-indole Fragment: Virtual Screening, Rational Design, and Biological Evaluation.
J. Chem. Inf. Model., 2024

OPTICS: An interactive online platform for photosensory and bio-functional proteins in optogenetic systems.
Comput. Biol. Medicine, 2024

2023
EMNPD: a comprehensive endophytic microorganism natural products database for prompt the discovery of new bioactive substances.
J. Cheminformatics, December, 2023

OBMeta: a comprehensive web server to analyze and validate gut microbial features and biomarkers for obesity-associated metabolic diseases.
Bioinform., December, 2023

An interpretable ensemble learning model facilitates early risk stratification of ischemic stroke in intensive care unit: Development and external validation of ICU-ISPM.
Comput. Biol. Medicine, November, 2023

Editorial: Harnessing the Power of Large Language Model-Based Chatbots for Scientific Discovery.
J. Chem. Inf. Model., September, 2023

RNAincoder: a deep learning-based encoder for RNA and RNA-associated interaction.
Nucleic Acids Res., July, 2023

Structure-Based Discovery of a Novel Allosteric Inhibitor against Human Dopamine Transporter.
J. Chem. Inf. Model., July, 2023

SoCube: an innovative end-to-end doublet detection algorithm for analyzing scRNA-seq data.
Briefings Bioinform., May, 2023

Systematic Description of the Content Variation of Natural Products (NPs): To Prompt the Yield of High-Value NPs and the Discovery of New Therapeutics.
J. Chem. Inf. Model., March, 2023

MecDDI: Clarified Drug-Drug Interaction Mechanism Facilitating Rational Drug Use and Potential Drug-Drug Interaction Prediction.
J. Chem. Inf. Model., March, 2023

DRESIS: the first comprehensive landscape of drug resistance information.
Nucleic Acids Res., January, 2023

M6AREG: m6A-centered regulation of disease development and drug response.
Nucleic Acids Res., January, 2023

DrugMAP: molecular atlas and pharma-information of all drugs.
Nucleic Acids Res., January, 2023

CovInter: interaction data between coronavirus RNAs and host proteins.
Nucleic Acids Res., January, 2023

A novel strategy for designing the magic shotguns for distantly related target pairs.
Briefings Bioinform., January, 2023

Label-free proteome quantification and evaluation.
Briefings Bioinform., January, 2023

Editorial: Machine Learning in Bio-cheminformatics.
J. Chem. Inf. Model., 2023

2022
Therapeutic target database update 2022: facilitating drug discovery with enriched comparative data of targeted agents.
Nucleic Acids Res., 2022

SYNBIP: synthetic binding proteins for research, diagnosis and therapy.
Nucleic Acids Res., 2022

NPCDR: natural product-based drug combination and its disease-specific molecular regulation.
Nucleic Acids Res., 2022

VARIDT 2.0: structural variability of drug transporter.
Nucleic Acids Res., 2022

Editorial on Machine Learning.
J. Chem. Inf. Model., 2022

Computational Chemistry in Asia.
J. Chem. Inf. Model., 2022

Application of Machine Learning in Spatial Proteomics.
J. Chem. Inf. Model., 2022

REGLIV: Molecular regulation data of diverse living systems facilitating current multiomics research.
Comput. Biol. Medicine, 2022

PFmulDL: a novel strategy enabling multi-class and multi-label protein function annotation by integrating diverse deep learning methods.
Comput. Biol. Medicine, 2022

A similarity-based deep learning approach for determining the frequencies of drug side effects.
Briefings Bioinform., 2022

ncRNAInter: a novel strategy based on graph neural network to discover interactions between lncRNA and miRNA.
Briefings Bioinform., 2022

Biological activities of drug inactive ingredients.
Briefings Bioinform., 2022

RNA-RNA interactions between SARS-CoV-2 and host benefit viral development and evolution during COVID-19 infection.
Briefings Bioinform., 2022

LargeMetabo: an out-of-the-box tool for processing and analyzing large-scale metabolomic data.
Briefings Bioinform., 2022

POSREG: proteomic signature discovered by simultaneously optimizing its reproducibility and generalizability.
Briefings Bioinform., 2022

ConSIG: consistent discovery of molecular signature from OMIC data.
Briefings Bioinform., 2022

2021
Functional characterization of disease/comorbidity-associated lncRNA.
Quant. Biol., December, 2021

Out-of-the-box deep learning prediction of pharmaceutical properties by broadly learned knowledge-based molecular representations.
Nat. Mach. Intell., 2021

INTEDE: interactome of drug-metabolizing enzymes.
Nucleic Acids Res., 2021

GIMICA: host genetic and immune factors shaping human microbiota.
Nucleic Acids Res., 2021

The mechanistic, diagnostic and therapeutic novel nucleic acids for hepatocellular carcinoma emerging in past score years.
Briefings Bioinform., 2021

The miRNA: a small but powerful RNA for COVID-19.
Briefings Bioinform., 2021

MetaFS: Performance assessment of biomarker discovery in metaproteomics.
Briefings Bioinform., 2021

Pharmacometabonomics: data processing and statistical analysis.
Briefings Bioinform., 2021

2020
VARIDT 1.0: variability of drug transporter database (Corrigendum).
Nucleic Acids Res., 2020

VARIDT 1.0: variability of drug transporter database.
Nucleic Acids Res., 2020

NOREVA: enhanced normalization and evaluation of time-course and multi-class metabolomic data.
Nucleic Acids Res., 2020

Therapeutic target database 2020: enriched resource for facilitating research and early development of targeted therapeutics.
Nucleic Acids Res., 2020

Consistent gene signature of schizophrenia identified by a novel feature selection strategy from comprehensive sets of transcriptomic data.
Briefings Bioinform., 2020

A novel bioinformatics approach to identify the consistently well-performing normalization strategy for current metabolomic studies.
Briefings Bioinform., 2020

A critical assessment of the feature selection methods used for biomarker discovery in current metaproteomics studies.
Briefings Bioinform., 2020

ANPELA: analysis and performance assessment of the label-free quantification workflow for metaproteomic studies.
Briefings Bioinform., 2020

Comprehensive assessment of nine docking programs on type II kinase inhibitors: prediction accuracy of sampling power, scoring power and screening power.
Briefings Bioinform., 2020

Clinical trials, progression-speed differentiating features and swiftness rule of the innovative targets of first-in-class drugs.
Briefings Bioinform., 2020

Protein functional annotation of simultaneously improved stability, accuracy and false discovery rate achieved by a sequence-based deep learning.
Briefings Bioinform., 2020

Convolutional neural network-based annotation of bacterial type IV secretion system effectors with enhanced accuracy and reduced false discovery.
Briefings Bioinform., 2020

Genome-wide identification and analysis of the eQTL lncRNAs in multiple sclerosis based on RNA-seq data.
Briefings Bioinform., 2020

2019
HawkDock: a web server to predict and analyze the protein-protein complex based on computational docking and MM/GBSA.
Nucleic Acids Res., 2019

Clustering Bioactive Molecules in 3D Chemical Space with Unsupervised Deep Learning.
CoRR, 2019

farPPI: a webserver for accurate prediction of protein-ligand binding structures for small-molecule PPI inhibitors by MM/PB(GB)SA methods.
Bioinform., 2019

2018
Therapeutic target database update 2018: enriched resource for facilitating bench-to-clinic research of targeted therapeutics.
Nucleic Acids Res., 2018

Cheminformatic Insight into the Differences between Terrestrial and Marine Originated Natural Products.
J. Chem. Inf. Model., 2018

The Comprehensive Assessment of the Normalization Methods Applied to Metabolomics Data.
Proceedings of the 2018 7th International Conference on Bioinformatics and Biomedical Science, 2018

2017
Discovery of Novel and Selective Adenosine A<sub>2A</sub> Receptor Antagonists for Treating Parkinson's Disease through Comparative Structure-Based Virtual Screening.
J. Chem. Inf. Model., June, 2017

NOREVA: normalization and evaluation of MS-based metabolomics data.
Nucleic Acids Res., 2017

HawkRank: a new scoring function for protein-protein docking based on weighted energy terms.
J. Cheminformatics, 2017

A protein network descriptor server and its use in studying protein, disease, metabolic and drug targeted networks.
Briefings Bioinform., 2017

2016
Therapeutic target database update 2016: enriched resource for bench to clinical drug target and targeted pathway information.
Nucleic Acids Res., 2016

2015
The Discrimination of Learning Styles by Bayes-Based Statistics: an Extended Study on ILS System.
Control. Intell. Syst., 2015

2014
Therapeutic target database update 2014: a resource for targeted therapeutics.
Nucleic Acids Res., 2014

2012
Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery.
Nucleic Acids Res., 2012

2010
Update of TTD: Therapeutic Target Database.
Nucleic Acids Res., 2010


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