Elsje Pienaar

According to our database, Elsje Pienaar authored at least 10 papers between 2006 and 2024.

Collaborative distances:

• Dijkstra number of six.
• Erdős number of five.

2024

Agent-based model predicts that layered structure and 3D movement work synergistically to reduce bacterial load in 3D in vitro models of tuberculosis granuloma.

Alexa Petrucciani, Alexis Hoerter, Leigh Kotze, Nelita Du Plessis, Elsje Pienaar

PLoS Comput. Biol., 2024

2023

Mathematical modeling indicates that regulatory inhibition of CD8+ T cell cytotoxicity can limit efficacy of IL-15 immunotherapy in cases of high pre-treatment SIV viral load.

Jonathan W. Cody, Amy L. Ellis-Connell, Shelby L. O'Connor, Elsje Pienaar

PLoS Comput. Biol., 2023

2021

Mathematical modeling of N-803 treatment in SIV-infected non-human primates.

Jonathan W. Cody, Amy L. Ellis-Connell, Shelby L. O'Connor, Elsje Pienaar

PLoS Comput. Biol., 2021

2017

Comparing efficacies of moxifloxacin, levofloxacin and gatifloxacin in tuberculosis granulomas using a multi-scale systems pharmacology approach.

Elsje Pienaar, Jansy Sarathy, Brendan Prideaux, Jillian Dietzold, Véronique Dartois, Denise E. Kirschner, Jennifer J. Linderman

PLoS Comput. Biol., 2017

2015

<i>In silico</i> evaluation and exploration of antibiotic tuberculosis treatment regimens.

Elsje Pienaar, Véronique Dartois, Jennifer J. Linderman, Denise E. Kirschner

BMC Syst. Biol., 2015

2012

A state-time epidemiology model of tuberculosis: Importance of re-infection.

Steve J. Viljoen, Elsje Pienaar, Hendrik J. Viljoen

Comput. Biol. Chem., 2012

2010

A model of tuberculosis transmission and intervention strategies in an urban residential area.

Elsje Pienaar, Aaron M. Fluitt, Scott E. Whitney, Alison G. Freifeld, Hendrik J. Viljoen

Comput. Biol. Chem., 2010

2008

A fundamental study of the PCR amplification of GC-rich DNA templates.

T. G. Mamedov, Elsje Pienaar, Scott E. Whitney, J. R. TerMaat, G. Carvill, R. Goliath, A. Subramanian, Hendrik J. Viljoen

Comput. Biol. Chem., 2008

2007

Ribosome kinetics and aa-tRNA competition determine rate and fidelity of peptide synthesis.

Aaron M. Fluitt, Elsje Pienaar, Hendrik J. Viljoen

Comput. Biol. Chem., 2007

2006

A quantitative model of error accumulation during PCR amplification.

Elsje Pienaar, Melanie Theron, Michael Nelson, Hendrik J. Viljoen

Comput. Biol. Chem., 2006