Douglas B. Kell

Orcid: 0000-0001-5838-7963

Affiliations:
  • University of Manchester, School of Chemistry, UK


According to our database1, Douglas B. Kell authored at least 56 papers between 1998 and 2020.

Collaborative distances:
  • Dijkstra number2 of four.
  • Erdős number3 of four.

Timeline

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Bibliography

2020
DeepGraphMolGen, a multi-objective, computational strategy for generating molecules with desirable properties: a graph convolution and reinforcement learning approach.
J. Cheminformatics, 2020

2018
PartsGenie: an integrated tool for optimizing and sharing synthetic biology parts.
Bioinform., 2018

Selenzyme: enzyme selection tool for pathway design.
Bioinform., 2018

2017
CodonGenie: optimised ambiguous codon design tools.
PeerJ Prepr., 2017

Analysis of drug-endogenous human metabolite similarities in terms of their maximum common substructures.
J. Cheminformatics, 2017

Evolutionary algorithms and synthetic biology for directed evolution: commentary on "on the mapping of genotype to phenotype in evolutionary algorithms" by Peter A. Whigham, Grant Dick, and James Maclaurin.
Genet. Program. Evolvable Mach., 2017

What do we need to build explainable AI systems for the medical domain?
CoRR, 2017

2016
Computing exponentially faster: Implementing a nondeterministic universal Turing machine using DNA.
CoRR, 2016

2015
Software review: the KNIME workflow environment and its applications in genetic programming and machine learning.
Genet. Program. Evolvable Mach., 2015

2014
GeneGenie: optimized oligomer design for directed evolution.
Nucleic Acids Res., 2014

2013
Path2Models: large-scale generation of computational models from biochemical pathway maps.
BMC Syst. Biol., 2013

A method for integrating and ranking the evidence for biochemical pathways by mining reactions from text.
Bioinform., 2013

2012
The genetic control of growth rate: a systems biology study in yeast.
BMC Syst. Biol., 2012

Improving metabolic flux predictions using absolute gene expression data.
BMC Syst. Biol., 2012

Extracting semantically enriched events from biomedical literature.
BMC Bioinform., 2012

Automated workflows for accurate mass-based putative metabolite identification in LC/MS-derived metabolomic datasets.
Bioinform., 2012

2011
The SuBliMinaL Toolbox: automating steps in the reconstruction of metabolic networks.
J. Integr. Bioinform., 2011

Interactions among oscillatory pathways in NF-kappa B signaling.
BMC Syst. Biol., 2011

Predicting the points of interaction of small molecules in the NF-κB pathway.
BMC Syst. Biol., 2011

2010
Further developments towards a genome-scale metabolic model of yeast.
BMC Syst. Biol., 2010

Systematic integration of experimental data and models in systems biology.
BMC Bioinform., 2010

Arcadia: a visualization tool for metabolic pathways.
Bioinform., 2010

Predictive models for population performance on real biological fitness landscapes.
Bioinform., 2010

Utopia documents: linking scholarly literature with research data.
Bioinform., 2010

2009
Deterministic mathematical models of the cAMP pathway in Saccharomyces cerevisiae.
BMC Syst. Biol., 2009

Visualising biological data: a semantic approach to tool and database integration.
BMC Bioinform., 2009

Information management for high content live cell imaging.
BMC Bioinform., 2009

KiPar, a tool for systematic information retrieval regarding parameters for kinetic modelling of yeast metabolic pathways.
Bioinform., 2009

2008
Defrosting the Digital Library: Bibliographic Tools for the Next Generation Web.
PLoS Comput. Biol., 2008

Facilitating the development of controlled vocabularies for metabolomics technologies with text mining.
BMC Bioinform., 2008

Performing statistical analyses on quantitative data in Taverna workflows: An example using R and maxdBrowse to identify differentially-expressed genes from microarray data.
BMC Bioinform., 2008

Automated manipulation of systems biology models using libSBML within Taverna workflows.
Bioinform., 2008

Bayesian inference of the sites of perturbations in metabolic pathways via Markov chain Monte Carlo.
Bioinform., 2008

The landscape adaptive particle swarm optimizer.
Appl. Soft Comput., 2008

Rapid prediction of optimum population size in genetic programming using a novel genotype -: fitness correlation.
Proceedings of the Genetic and Evolutionary Computation Conference, 2008

Molecular Structure Elucidation Using Ant Colony Optimization: A Preliminary Study.
Proceedings of the Ant Colony Optimization and Swarm Intelligence, 2008

2007
Multiobjective Optimization in Bioinformatics and Computational Biology.
IEEE ACM Trans. Comput. Biol. Bioinform., 2007

Towards a mathematical model of the cAMP pathway in S. cerevisiae.
BMC Syst. Biol., 2007

Peptide detectability following ESI mass spectrometry: prediction using genetic programming.
Proceedings of the Genetic and Evolutionary Computation Conference, 2007

Improving Data Fitting of a Signal Transduction Model by Global Sensitivity Analysis.
Proceedings of the American Control Conference, 2007

Taverna/<sup>my</sup>Grid: Aligning a Workflow System with the Life Sciences Community.
Proceedings of the Workflows for e-Science, Scientific Workflows for Grids., 2007

2006
MeMo: a hybrid SQL/XML approach to metabolomic data management for functional genomics.
BMC Bioinform., 2006

2005
maxdLoad2 and maxdBrowse: standards-compliant tools for microarray experimental annotation, data management and dissemination.
BMC Bioinform., 2005

Computational cluster validation in post-genomic data analysis.
Bioinform., 2005

2003
Landscape State Machines: Tools for Evolutionary Algorithm Performance Analyses and Landscape/Algorithm Mapping.
Proceedings of the Applications of Evolutionary Computing, 2003

2002
Observed dynamics of Large Scale Parallel Evolutionary Algorithms with Implications for protein Engineering.
Proceedings of the Recent Advances in Simulated Evolution and Learning [extended and revised papers selected from the 4th Asia-Pacific Conference on Simulated Evolution and Learning, 2002

On Fitness Distributions and Expected Fitness Gain of Mutation Rates in Parallel Evolutionary Algorithms.
Proceedings of the Parallel Problem Solving from Nature, 2002

Fitness Gains and Mutation Patterns: Deriving Mutation Rates by Exploiting Landscape Data.
Proceedings of the Seventh Workshop on Foundations of Genetic Algorithms, 2002

2001
Developing a Logical Model of Yeast Metabolism.
Electron. Trans. Artif. Intell., 2001

Combining Inductive Logic Programming, Active Learning and Robotics to Discover the Function of Genes.
Electron. Trans. Artif. Intell., 2001

MEG (Model Extender for Gepasi): a program for the modelling of complex, heterogeneous, cellular systems.
Bioinform., 2001

Compression of proteome gel images using complex wavelet transform.
Proceedings of the Computer science and biology: Proceedings of the German Conference on Bioinformatics, 2001

Spectral analysis via supervised genetic search with application-specific mutations.
Proceedings of the 2001 Congress on Evolutionary Computation, 2001

2000
Explanatory Analysis of the Metabolome Using Genetic Programming of Simple, Interpretable Rules.
Genet. Program. Evolvable Mach., 2000

Genomic computing: explanatory modelling for functional genomics.
Proceedings of the Genetic and Evolutionary Computation Conference (GECCO '00), 2000

1998
Non-linear optimization of biochemical pathways: applications to metabolic engineering and parameter estimation.
Bioinform., 1998


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