Denis Fourches

Orcid: 0000-0001-5642-8303

Affiliations:
  • North Carolina State University, Department of Chemistry, Raleigh, NC, USA


According to our database1, Denis Fourches authored at least 29 papers between 2004 and 2021.

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Bibliography

2021
SMILES Pair Encoding: A Data-Driven Substructure Tokenization Algorithm for Deep Learning.
J. Chem. Inf. Model., 2021

2020
Benchmarking 2D/3D/MD-QSAR Models for Imatinib Derivatives: How Far Can We Predict?
J. Chem. Inf. Model., 2020

SIME: synthetic insight-based macrolide enumerator to generate the V1B library of 1 billion macrolides.
J. Cheminformatics, 2020

Inductive transfer learning for molecular activity prediction: Next-Gen QSAR Models with MolPMoFiT.
J. Cheminformatics, 2020

2019
Identifying individual risk rare variants using protein structure guided local tests (POINT).
PLoS Comput. Biol., 2019

Cheminformatics approach to exploring and modeling trait-associated metabolite profiles.
J. Cheminformatics, 2019

2018
Chemistry-Wide Association Studies (CWAS): A Novel Framework for Identifying and Interpreting Structure-Activity Relationships.
J. Chem. Inf. Model., 2018

Cheminformatics-based enumeration and analysis of large libraries of macrolide scaffolds.
J. Cheminformatics, 2018

Adverse drug reactions triggered by the common HLA-B*57: 01 variant: virtual screening of DrugBank using 3D molecular docking.
J. Cheminformatics, 2018

Exploring drug space with ChemMaps.com.
Bioinform., 2018

2017
Characterizing the Chemical Space of ERK2 Kinase Inhibitors Using Descriptors Computed from Molecular Dynamics Trajectories.
J. Chem. Inf. Model., June, 2017

Adverse drug reactions triggered by the common HLA-B*57: 01 variant: a molecular docking study.
J. Cheminformatics, 2017

RealityConvert: a tool for preparing 3D models of biochemical structures for augmented and virtual reality.
Bioinform., 2017

2016
Trust, but Verify II: A Practical Guide to Chemogenomics Data Curation.
J. Chem. Inf. Model., 2016

Cheminformatics-aided pharmacovigilance: application to Stevens-Johnson Syndrome.
J. Am. Medical Informatics Assoc., 2016

2015
Target-Specific Native/Decoy Pose Classifier Improves the Accuracy of Ligand Ranking in the CSAR 2013 Benchmark.
J. Chem. Inf. Model., 2015

2014
Data Set Modelability by QSAR.
J. Chem. Inf. Model., 2014

Chemistry-wide association studies (CWAS) to determine joint toxicity effects of co-occurring chemical features.
J. Cheminformatics, 2014

Fishing out the signal in polypharmacological high-throughput screening data using novel navigator cheminformatics software.
J. Cheminformatics, 2014

HTS navigator: freely accessible cheminformatics software for analyzing high-throughput screening data.
Bioinform., 2014

2013
Discovery of Novel Antimalarial Compounds Enabled by QSAR-Based Virtual Screening.
J. Chem. Inf. Model., 2013

Predicting Binding Affinity of CSAR Ligands Using Both Structure-Based and Ligand-Based Approaches.
J. Chem. Inf. Model., 2013

2010
Applicability Domains for Classification Problems: Benchmarking of Distance to Models for Ames Mutagenicity Set.
J. Chem. Inf. Model., 2010

Trust, But Verify: On the Importance of Chemical Structure Curation in Cheminformatics and QSAR Modeling Research.
J. Chem. Inf. Model., 2010

2008
Combinatorial QSAR Modeling of Chemical Toxicants Tested against Tetrahymena pyriformis.
J. Chem. Inf. Model., 2008

Critical Assessment of QSAR Models of Environmental Toxicity against <i>Tetrahymena pyriformis: </i> Focusing on Applicability Domain and Overfitting by Variable Selection.
J. Chem. Inf. Model., 2008

2006
Benchmarking of Linear and Nonlinear Approaches for Quantitative Structure-Property Relationship Studies of Metal Complexation with Ionophores.
J. Chem. Inf. Model., 2006

2005
Substructural fragments: an universal language to encode reactions, molecular and supramolecular structures.
J. Comput. Aided Mol. Des., 2005

2004
"In Silico" Design of New Uranyl Extractants Based on Phosphoryl-Containing Podands: QSPR Studies, Generation and Screening of Virtual Combinatorial Library, and Experimental Tests.
J. Chem. Inf. Model., 2004


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