Dan M. Roden

According to our database, Dan M. Roden authored at least 36 papers between 2006 and 2024.

Collaborative distances:

• Dijkstra number of four.
• Erdős number of three.

2024

Leveraging generative AI to prioritize drug repurposing candidates for Alzheimer's disease with real-world clinical validation.

Chao Yan, Monika E. Grabowska, Alyson L. Dickson, Bingshan Li, Zhexing Wen, Dan M. Roden, C. Michael Stein, Peter J. Embí, Josh F. Peterson, QiPing Feng, Bradley A. Malin, Wei-Qi Wei

npj Digit. Medicine, 2024

PheMIME: an interactive web app and knowledge base for phenome-wide, multi-institutional multimorbidity analysis.

Siwei Zhang, Nick Strayer, Tess Vessels, Karmel Choi, Geoffrey W. Wang, Yajing Li, Cosmin Adrian Bejan, Ryan S. Hsi, Alex Bick, Digna R. Velez Edwards, Michael R. Savona, Elizabeth J. Phillips, Jill M. Pulley, Wesley H. Self, Consuelo H. Wilkins, Dan M. Roden, Jordan W. Smoller, Douglas M. Ruderfer, Yaomin Xu

J. Am. Medical Informatics Assoc., 2024

Large language models facilitate the generation of electronic health record phenotyping algorithms.

Chao Yan, Henry H. Ong, Monika E. Grabowska, Matthew S. Krantz, Wu-Chen Su, Alyson L. Dickson, Josh F. Peterson, QiPing Feng, Dan M. Roden, C. Michael Stein, Vern Eric Kerchberger, Bradley A. Malin, Wei-Qi Wei

J. Am. Medical Informatics Assoc., 2024

2023

Next-generation phenotyping: introducing phecodeX for enhanced discovery research in medical phenomics.

Megan M. Shuey, William W. Stead, Ida Aka, April L. Barnado, Lisa Bastarache, Elly Brokamp, Meredith Campbell, Robert J. Carroll, Jeffrey A. Goldstein, Adam Lewis, Beth A. Malow, Jonathan D. Mosley, Travis Osterman, Dolly A Padovani-Claudio, Andrea Ramirez, Dan M. Roden, Bryce A Schuler, Edward Siew, Jennifer Sucre, Isaac Thomsen, Rory J. Tinker, Sara Van Driest, Colin Walsh, Jeremy L. Warner, Quinn Stanton Wells, Lee E. Wheless

Bioinform., October, 2023

Interactive network-based clustering and investigation of multimorbidity association matrices with associationSubgraphs.

Nick Strayer, Siwei Zhang, Lydia Yao, Tess Vessels, Cosmin Adrian Bejan, Ryan S. Hsi, Jana K. Shirey-Rice, Justin M. Balko, Douglas B. Johnson, Elizabeth J. Phillips, Alex Bick, Todd L. Edwards, Digna R. Velez Edwards, Jill M. Pulley, Quinn Stanton Wells, Michael R. Savona, Nancy J. Cox, Dan M. Roden, Douglas M. Ruderfer, Yaomin Xu

Bioinform., January, 2023

2022

The <i>All of Us</i> Research Program: Data quality, utility, and diversity.

Andrea H. Ramirez, Lina M. Sulieman, David J. Schlueter, Alese E. Halvorson, Jun Qian, Francis Ratsimbazafy, Roxana Loperena-Cortes, Kelsey R. Mayo, Melissa A. Basford, Nicole Deflaux, Karthik Muthuraman, Karthik Natarajan, Abel N. Kho, Hua Xu, Consuelo H. Wilkins, Hoda Anton-Culver, Eric Boerwinkle, Mine Cicek, Cheryl R. Clark, Elizabeth Cohn, Lucila Ohno-Machado, Sheri D. Schully, Brian K. Ahmedani, Maria Argos, Robert M. Cronin, Christopher J. O'Donnell, Mona Fouad, David B. Goldstein, Philip Greenland, Scott J. Hebbring, Elizabeth W. Karlson, Parinda Khatri, Bruce Korf, Jordan W. Smoller, Stephen Sodeke, John Wilbanks, Justin Hentges, Stephen Mockrin, Christopher Lunt, Stephanie A. Devaney, Kelly Gebo, Joshua C. Denny, Robert J. Carroll, David Glazer, Paul A. Harris, George Hripcsak, Anthony A. Philippakis, Dan M. Roden

Patterns, 2022

A research agenda to support the development and implementation of genomics-based clinical informatics tools and resources.

Ken Wiley, Laura Findley, Madison Goldrich, Tejinder K. Rakhra-Burris, Ana Stevens, Pamela Williams, Carol J. Bult, Rex L. Chisholm, Patricia Deverka, Geoffrey S. Ginsburg, Eric D. Green, Gail P. Jarvik, George A. Mensah, Erin Ramos, Mary V. Relling, Dan M. Roden, Robb Rowley, Gil Alterovitz, Samuel J. Aronson, Lisa Bastarache, James J. Cimino, Erin L. Crowgey, Guilherme Del Fiol, Robert R. Freimuth, Mark A. Hoffman, Janina M. Jeff, Kevin B. Johnson, Kensaku Kawamoto, Subha Madhavan, Eneida A. Mendonça, Lucila Ohno-Machado, Siddharth Pratap, Casey Overby Taylor, Marylyn D. Ritchie, Nephi Walton, Chunhua Weng, Teresa Zayas-Cabán, Teri A. Manolio, Marc S. Williams

J. Am. Medical Informatics Assoc., 2022

Comparing medical history data derived from electronic health records and survey answers in the <i>All of Us</i> Research Program.

Lina M. Sulieman, Robert M. Cronin, Robert J. Carroll, Karthik Natarajan, Kayla Marginean, Brandy Mapes, Dan M. Roden, Paul A. Harris, Andrea H. Ramirez

J. Am. Medical Informatics Assoc., 2022

2021

A retrospective approach to evaluating potential adverse outcomes associated with delay of procedures for cardiovascular and cancer-related diagnoses in the context of COVID-19.

Neil S. Zheng, Jeremy L. Warner, Travis J. Osterman, Quinn Stanton Wells, Xiao-Ou Shu, Stephen A. Deppen, Seth J. Karp, Shon Dwyer, QiPing Feng, Nancy J. Cox, Josh F. Peterson, C. Michael Stein, Dan M. Roden, Kevin B. Johnson, Wei-Qi Wei

J. Biomed. Informatics, 2021

Phenotyping coronavirus disease 2019 during a global health pandemic: Lessons learned from the characterization of an early cohort.

Sarah DeLozier, Sarah Bland, Melissa McPheeters, Quinn Stanton Wells, Eric Farber-Eger, Cosmin Adrian Bejan, Daniel Fabbri, S. Trent Rosenbloom, Dan M. Roden, Kevin B. Johnson, Wei-Qi Wei, Josh F. Peterson, Lisa Bastarache

J. Biomed. Informatics, 2021

DDIWAS: High-throughput electronic health record-based screening of drug-drug interactions.

Patrick Wu, Scott D. Nelson, Juan Zhao, Cosby A. Stone Jr., QiPing Feng, Qingxia Chen, Eric A. Larson, Bingshan Li, Nancy J. Cox, C. Michael Stein, Elizabeth Phillips, Dan M. Roden, Joshua C. Denny, Wei-Qi Wei

J. Am. Medical Informatics Assoc., 2021

Real-time clinical note monitoring to detect conditions for rapid follow-up: A case study of clinical trial enrollment in drug-induced torsades de pointes and Stevens-Johnson syndrome.

Sarah DeLozier, Peter Speltz, Jason Brito, Leigh Anne Tang, Janey Wang, Joshua C. Smith, Dario A. Giuse, Elizabeth Phillips, Kristina Williams, T. Stephen Strickland, Giovanni Davogustto, Dan M. Roden, Joshua C. Denny

J. Am. Medical Informatics Assoc., 2021

2020

A structural variation reference for medical and population genetics.

Ryan L. Collins, Harrison Brand, Konrad J. Karczewski, Xuefang Zhao, Jessica Alföldi, Laurent C. Francioli, Amit V. Khera, Chelsea Lowther, Laura D. Gauthier, Harold Wang, Nicholas A. Watts, Matthew Solomonson, Alexander Baumann, Ruchi Munshi, Mark Walker, Christopher W. Whelan, Yongqing Huang, Ted Brookings, Ted Sharpe, Matthew R. Stone, Elise Valkanas, Jack Fu, Grace Tiao, Kristen M. Laricchia, Valentín Ruano-Rubio, Christine Stevens, Namrata Gupta, Caroline Cusick, Lauren Margolin, Irina M. Armean, Eric Banks, Louis Bergelson, Kristian Cibulskis, Kristen M. Connolly, Miguel Covarrubias, Beryl B. Cummings, Mark J. Daly, Stacey Donnelly, Yossi Farjoun, Steven Ferriera, Stacey Gabriel, Jeff Gentry, Thibault Jeandet, Diane Kaplan, Christopher Llanwarne, Eric V. Minikel, Benjamin M. Neale, Sam Novod, Anne H. O'Donnell-Luria, Nikelle Petrillo, Timothy Poterba, David Roazen, Andrea Saltzman, Kaitlin E. Samocha, Molly Schleicher, Cotton Seed, José Soto, Kathleen Tibbetts, Charlotte Tolonen, Christopher Vittal, Gordon Wade, Arcturus Wang, Qingbo Wang, James S. Ware, Ben Weisburd, Nicola Whiffin, Carlos A. Aguilar Salinas, Tariq Ahmad, Christine M. Albert, Diego Ardissino, Gil Atzmon, John Barnard, Laurent Beaugerie, Emelia J. Benjamin, Michael Boehnke, Lori L. Bonnycastle, Erwin P. Bottinger, Donald W. Bowden, Matthew J. Bown, John C. Chambers, Juliana C. Chan, Daniel Chasman, Judy Cho, Mina K. Chung, Bruce Cohen, Adolfo Correa, Dana Dabelea, Dawood Darbar, Ravindranath Duggirala, Josée Dupuis, Patrick T. Ellinor, Roberto Elosua, Jeanette Erdmann, Tõnu Esko, Martti Färkkilä, Jose Florez, Andre Franke, Gad Getz, Benjamin Glaser, Stephen J. Glatt, David Goldstein, Clicerio Gonzalez, Leif Groop, Christopher A. Haiman, Craig Hanis, Matthew Harms, Mikko Hiltunen, Matti M. Holi, Christina M. Hultman, Mikko Kallela, Jaakko Kaprio, Sekar Kathiresan, Bong-Jo Kim, Young Jin Kim, George Kirov, Jaspal Kooner, Seppo Koskinen, Harlan M. Krumholz, Subra Kugathasan, Soo Heon Kwak, Markku Laakso, Terho Lehtimäki, Ruth J. F. Loos, Steven A. Lubitz, Ronald C. W. Ma, Daniel G. MacArthur, Jaume Marrugat, Kari M. Mattila, Steven A. McCarroll, Mark I. McCarthy, Dermot McGovern, Ruth McPherson, James B. Meigs, Olle Melander, Andres Metspalu, Peter M. Nilsson, Michael C. O'Donovan, Dost Öngür, Lorena Orozco, Michael J. Owen, Colin N. A. Palmer, Aarno Palotie, Kyong Soo Park, Carlos Pato, Ann E. Pulver, Nazneen Rahman, Anne M. Remes, John D. Rioux, Samuli Ripatti, Dan M. Roden, Danish Saleheen, Veikko Salomaa, Nilesh J. Samani, Jeremiah Scharf, Heribert Schunkert, Moore B. Shoemaker, Pamela Sklar, Hilkka Soininen, Harry Sokol, Tim Spector, Patrick F. Sullivan, Jaana Suvisaari, E. Shyong Tai, Yik Ying Teo, Tuomi Tiinamaija, Ming Tsuang, Dan Turner, Teresa Tusie-Luna, Erkki Vartiainen, Hugh Watkins, Rinse K. Weersma, Maija Wessman, James G. Wilson, Ramnik J. Xavier, Kent D. Taylor, Henry J. Lin, Stephen S. Rich, Wendy S. Post, Yii-Der Ida Chen, Jerome I. Rotter, Chad Nusbaum, Anthony A. Philippakis, Eric S. Lander, Michael E. Talkowski

Nat., 2020

PheMap: a multi-resource knowledge base for high-throughput phenotyping within electronic health records.

Neil S. Zheng, QiPing Feng, Vern Eric Kerchberger, Juan Zhao, Todd L. Edwards, Nancy J. Cox, C. Michael Stein, Dan M. Roden, Joshua C. Denny, Wei-Qi Wei

J. Am. Medical Informatics Assoc., 2020

The All of Us Research Program Researcher Workbench: Cloud based access and analytics to advance precision medicine.

Andrea H. Ramirez, Kelsey R. Mayo, Robert J. Carroll, Karthik Muthuraman, Melissa A. Basford, David Glazer, Paul A. Harris, Anthony A. Philippakis, Dan M. Roden

Proceedings of the AMIA 2020, 2020

The All of Us Research Program Researcher Workbench Phenotype Library: Five Disease Implementations.

Izabelle P. Humes, Roxana Loperena-Cortes, Melissa A. Basford, Kelsey R. Mayo, Joseph DiPaolo, David J. Schlueter, Jun Qian, Wei-Qi Wei, Robert J. Carroll, David Glazer, Paul A. Harris, Anthony A. Philippakis, Dan M. Roden, Andrea H. Ramirez

Proceedings of the AMIA 2020, 2020

Real-time Clinical Note Monitoring to Detect Conditions for Follow-up: a Case Study of Clinical Trial Enrollment in Drug-induced Torsades de Pointes and Stevens-Johnson Syndrome.

Sarah DeLozier, Peter Speltz, Jason Brito, Leigh Anne Tang, Janey Wang, Joshua C. Smith, Dario A. Giuse, Elizabeth Phillips, Kristina Williams, Teresa Strickland, Giovanni Davogustto, Dan M. Roden, Joshua C. Denny

Proceedings of the AMIA 2020, 2020

2019

Improving the phenotype risk score as a scalable approach to identifying patients with Mendelian disease.

Lisa Bastarache, Jacob J. Hughey, Jeffery A. Goldstein, Julie A. Bastraache, Satya Das, Neil Charles Zaki, Chenjie Zeng, Leigh Anne Tang, Dan M. Roden, Joshua C. Denny

J. Am. Medical Informatics Assoc., 2019

2018

A case study evaluating the portability of an executable computable phenotype algorithm across multiple institutions and electronic health record environments.

Jennifer A. Pacheco, Luke V. Rasmussen, Richard C. Kiefer, Thomas R. Campion Jr., Peter Speltz, Robert J. Carroll, Sarah C. Stallings, Huan Mo, Monika Ahuja, Guoqian Jiang, Eric R. LaRose, Peggy L. Peissig, Ning Shang, Barbara Benoit, Vivian S. Gainer, Kenneth Borthwick, Kathryn L. Jackson, Ambrish Sharma, Andy Yizhou Wu, Abel N. Kho, Dan M. Roden, Jyotishman Pathak, Joshua C. Denny, William K. Thompson

J. Am. Medical Informatics Assoc., 2018

Evaluating statistical approaches to leverage large clinical datasets for uncovering therapeutic and adverse medication effects.

Leena Choi, Robert J. Carroll, Cole Beck, Jonathan D. Mosley, Dan M. Roden, Joshua C. Denny, Sara L. Van Driest

Bioinform., 2018

Evaluation of a Novel System to Enhance Clinicians' Recognition of Preadmission Adverse Drug Reactions.

Joshua C. Smith, Qingxia Chen, Joshua C. Denny, Dan M. Roden, Kevin B. Johnson, Randolph A. Miller

Appl. Clin. Inform., 2018

2017

Evaluating electronic health record data sources and algorithmic approaches to identify hypertensive individuals.

Pedro L. Teixeira, Wei-Qi Wei, Robert M. Cronin, Huan Mo, Jacob P. VanHouten, Robert J. Carroll, Eric LaRose, Lisa Bastarache, S. Trent Rosenbloom, Todd L. Edwards, Dan M. Roden, Thomas A. Lasko, Richard A. Dart, Anne M. Nikolai, Peggy L. Peissig, Joshua C. Denny

J. Am. Medical Informatics Assoc., 2017

Strategies for Equitable Pharmacogenomic-Guided Warfarin Dosing Among European and African American Individuals in a Clinical Population.

Laura K. Wiley, Jacob P. VanHouten, David Samuels, Melinda Aldrich, Dan M. Roden, Josh F. Peterson, Joshua C. Denny

Proceedings of the Biocomputing 2017: Proceedings of the Pacific Symposium, 2017

A comparative study of different methods for automatic identification of clopidogrel-induced bleedings in electronic health records.

Hee-Jin Lee, Min Jiang, Yonghui Wu, Christian Shaffer, John H. Cleator, Eitan Friedman, Joshua P. Lewis, Dan M. Roden, Joshua C. Denny, Hua Xu

Proceedings of the Summit on Clinical Research Informatics, 2017

2016

PheKB: a catalog and workflow for creating electronic phenotype algorithms for transportability.

Jacqueline Kirby, Peter Speltz, Luke V. Rasmussen, Melissa A. Basford, Omri Gottesman, Peggy L. Peissig, Jennifer A. Pacheco, Gerard Tromp, Jyotishman Pathak, David S. Carrell, Stephen B. Ellis, Todd Lingren, William K. Thompson, Guergana Savova, Jonathan L. Haines, Dan M. Roden, Paul A. Harris, Joshua C. Denny

J. Am. Medical Informatics Assoc., 2016

2015

Deciphering Signaling Pathway Networks to Understand the Molecular Mechanisms of Metformin Action.

Jingchun Sun, Min Zhao, Peilin Jia, Lily Wang, Yonghui Wu, Carissa Iverson, Yubo Zhou, Erica A. Bowton, Dan M. Roden, Joshua C. Denny, Melinda C. Aldrich, Hua Xu, Zhongming Zhao

PLoS Comput. Biol., 2015

Validating drug repurposing signals using electronic health records: a case study of metformin associated with reduced cancer mortality.

Hua Xu, Melinda C. Aldrich, Qingxia Chen, Hongfang Liu, Neeraja B. Peterson, Qi Dai, Mia A. Levy, Anushi Shah, Han Xue, Xiaoyang Ruan, Min Jiang, Ying Li, Jamii St Julien, Jeremy L. Warner, Carol Friedman, Dan M. Roden, Joshua C. Denny

J. Am. Medical Informatics Assoc., 2015

Desiderata for computable representations of electronic health records-driven phenotype algorithms.

Huan Mo, William K. Thompson, Luke V. Rasmussen, Jennifer A. Pacheco, Guoqian Jiang, Richard C. Kiefer, Qian Zhu, Jie Xu, Enid N. H. Montague, David S. Carrell, Todd Lingren, Frank D. Mentch, Yizhao Ni, Firas H. Wehbe, Peggy L. Peissig, Gerard Tromp, Eric B. Larson, Christopher G. Chute, Jyotishman Pathak, Joshua C. Denny, Peter Speltz, Abel N. Kho, Gail P. Jarvik, Cosmin Adrian Bejan, Marc S. Williams, Kenneth Borthwick, Terrie E. Kitchner, Dan M. Roden, Paul A. Harris

J. Am. Medical Informatics Assoc., 2015

2014

Size matters: How population size influences genotype-phenotype association studies in anonymized data.

Raymond Heatherly, Joshua C. Denny, Jonathan L. Haines, Dan M. Roden, Bradley A. Malin

J. Biomed. Informatics, 2014

Utilization of an EMR-Biorepository to Identify the Genetic Predictors of Calcineurin-Inhibitor Toxicity in Heart Transplant Recipients.

Matthew Oetjens, William S. Bush, Kelly A. Birdwell, Holli H. Dilks, Erica A. Bowton, Joshua C. Denny, Russell A. Wilke, Dan M. Roden, Dana C. Crawford

Proceedings of the Biocomputing 2014: Proceedings of the Pacific Symposium, 2014

Replication of SCN5A Associations with Electrocardiographic Traits in African Americans from Clinical and Epidemiologic Studies.

Janina M. Jeff, Kristin Brown-Gentry, Robert J. Goodloe, Marylyn D. Ritchie, Joshua C. Denny, Abel N. Kho, Loren L. Armstrong, Bob McClellan Jr., Ping Mayo, Melissa Allen, Hailing Jin, Niloufar B. Gillani, Nathalie Schnetz-Boutaud, Holli H. Dilks, Melissa A. Basford, Jennifer A. Pacheco, Gail P. Jarvik, Rex L. Chisholm, Dan M. Roden, M. Geoffrey Hayes, Dana C. Crawford

Proceedings of the Applications of Evolutionary Computation - 17th European Conference, 2014

2011

Facilitating pharmacogenetic studies using electronic health records and natural-language processing: a case study of warfarin.

Hua Xu, Min Jiang, Matthew Oetjens, Erica A. Bowton, Andrea H. Ramirez, Janina M. Jeff, Melissa A. Basford, Jill M. Pulley, James D. Cowan, Xiaoming Wang, Marylyn D. Ritchie, Daniel R. Masys, Dan M. Roden, Dana C. Crawford, Joshua C. Denny

J. Am. Medical Informatics Assoc., 2011

Visual Integration of Results from a Large Dna Biobank (Biovu) Using Synthesis-View.

Sarah A. Pendergrass, Scott M. Dudek, Dan M. Roden, Dana C. Crawford, Marylyn D. Ritchie

Proceedings of the Biocomputing 2011: Proceedings of the Pacific Symposium, 2011

2010

An analytical approach to characterize morbidity profile dissimilarity between distinct cohorts using electronic medical records.

Jonathan S. Schildcrout, Melissa A. Basford, Jill M. Pulley, Daniel R. Masys, Dan M. Roden, Deede Wang, Christopher G. Chute, Iftikhar J. Kullo, David Carrell, Peggy L. Peissig, Abel N. Kho, Joshua C. Denny

J. Biomed. Informatics, 2010

PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations.

Joshua C. Denny, Marylyn D. Ritchie, Melissa A. Basford, Jill M. Pulley, Lisa Bastarache, Kristin Brown-Gentry, Deede Wang, Daniel R. Masys, Dan M. Roden, Dana C. Crawford

Bioinform., 2010

2006

Risk Factor Interactions and Genetic Effects Associated with Post-Operative Atrial Fibrillation.

Alison A. Motsinger, Brian S. Donahue, Nancy J. Brown, Dan M. Roden, Marylyn D. Ritchie

Proceedings of the Biocomputing 2006, 2006