Chao Shen

Orcid: 0000-0003-2783-5529

Affiliations:
  • Zhejiang University, College of Pharmaceutical Sciences, Hangzhou, China
  • CarbonSilicon AI Technology Co., Ltd, Hangzhou, Zhejiang, China


According to our database1, Chao Shen authored at least 25 papers between 2019 and 2024.

Collaborative distances:
  • Dijkstra number2 of four.
  • Erdős number3 of four.

Timeline

Legend:

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Links

Online presence:

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Bibliography

2024
Comprehensive Evaluation of 10 Docking Programs on a Diverse Set of Protein-Cyclic Peptide Complexes.
J. Chem. Inf. Model., 2024

DrugFlow: An AI-Driven One-Stop Platform for Innovative Drug Discovery.
J. Chem. Inf. Model., 2024

Token-Mol 1.0: Tokenized drug design with large language model.
CoRR, 2024

2023
TB-IECS: an accurate machine learning-based scoring function for virtual screening.
J. Cheminformatics, December, 2023

ResGen is a pocket-aware 3D molecular generation model based on parallel multiscale modelling.
Nat. Mac. Intell., September, 2023

ML-PLIC: a web platform for characterizing protein-ligand interactions and developing machine learning-based scoring functions.
Briefings Bioinform., September, 2023

Can molecular dynamics simulations improve predictions of protein-ligand binding affinity with machine learning?
Briefings Bioinform., March, 2023

PROTAC-DB 2.0: an updated database of PROTACs.
Nucleic Acids Res., January, 2023

Learning with uncertainty to accelerate the discovery of histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitors.
Briefings Bioinform., January, 2023

Efficient and accurate large library ligand docking with KarmaDock.
Nat. Comput. Sci., 2023

2022
VGSC-DB: an online database of voltage-gated sodium channels.
J. Cheminformatics, 2022

2021
PROTAC-DB: an online database of PROTACs.
Nucleic Acids Res., 2021

ASFP (Artificial Intelligence based Scoring Function Platform): a web server for the development of customized scoring functions.
J. Cheminformatics, 2021

The impact of cross-docked poses on performance of machine learning classifier for protein-ligand binding pose prediction.
J. Cheminformatics, 2021

Could graph neural networks learn better molecular representation for drug discovery? A comparison study of descriptor-based and graph-based models.
J. Cheminformatics, 2021

Identification of active molecules against Mycobacterium tuberculosis through machine learning.
Briefings Bioinform., 2021

Improving structure-based virtual screening performance via learning from scoring function components.
Briefings Bioinform., 2021

Do we need different machine learning algorithms for QSAR modeling? A comprehensive assessment of 16 machine learning algorithms on 14 QSAR data sets.
Briefings Bioinform., 2021

Accuracy or novelty: what can we gain from target-specific machine-learning-based scoring functions in virtual screening?
Briefings Bioinform., 2021

Can machine learning consistently improve the scoring power of classical scoring functions? Insights into the role of machine learning in scoring functions.
Briefings Bioinform., 2021

Beware of the generic machine learning-based scoring functions in structure-based virtual screening.
Briefings Bioinform., 2021

2020
Improving Docking-Based Virtual Screening Ability by Integrating Multiple Energy Auxiliary Terms from Molecular Docking Scoring.
J. Chem. Inf. Model., 2020

ADMET evaluation in drug discovery. 20. Prediction of breast cancer resistance protein inhibition through machine learning.
J. Cheminformatics, 2020

Comprehensive assessment of nine docking programs on type II kinase inhibitors: prediction accuracy of sampling power, scoring power and screening power.
Briefings Bioinform., 2020

2019
ADMET Evaluation in Drug Discovery. 19. Reliable Prediction of Human Cytochrome P450 Inhibition Using Artificial Intelligence Approaches.
J. Chem. Inf. Model., 2019


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