Chang-Guo Zhan

Orcid: 0000-0002-4128-7269

According to our database1, Chang-Guo Zhan authored at least 17 papers between 2003 and 2023.

Collaborative distances:
  • Dijkstra number2 of five.
  • Erdős number3 of four.

Timeline

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Bibliography

2023
Free energy perturbation-based large-scale virtual screening for effective drug discovery against COVID-19.
Int. J. High Perform. Comput. Appl., 2023

Multi-objective Molecular Optimization for Opioid Use Disorder Treatment Using Generative Network Complex.
CoRR, 2023

2019
In Silico Observation of the Conformational Opening of the Glutathione-Binding Site of Microsomal Prostaglandin E2 Synthase-1.
J. Chem. Inf. Model., 2019

2014
Application of the 4D Fingerprint Method with a Robust Scoring Function for Scaffold-Hopping and Drug Repurposing Strategies.
J. Chem. Inf. Model., 2014

Novel Mycosin Protease MycP<sub>1</sub> Inhibitors Identified by Virtual Screening and 4D Fingerprints.
J. Chem. Inf. Model., 2014

2013
Computational gibberellin-binding channel discovery unraveling the unexpected perception mechanism of hormone signal by gibberellin receptor.
J. Comput. Chem., 2013

2012
Modeling of Pharmacokinetics of Cocaine in Human Reveals the Feasibility for Development of Enzyme Therapies for Drugs of Abuse.
PLoS Comput. Biol., 2012

Ligand-Based Virtual Screening Approach Using a New Scoring Function.
J. Chem. Inf. Model., 2012

2010
Computational determination of fundamental pathway and activation barriers for acetohydroxyacid synthase-catalyzed condensation reactions of alpha-keto acids.
J. Comput. Chem., 2010

2009
Computational Simulations of the Interactions between Acetyl-Coenzyme-A Carboxylase and Clodinafop: Resistance Mechanism Due to Active and Nonactive Site Mutations.
J. Chem. Inf. Model., 2009

2008
Combined 3D-QSAR Modeling and Molecular Docking Study on Indolinone Derivatives as Inhibitors of 3-Phosphoinositide-Dependent Protein Kinase-1.
J. Chem. Inf. Model., 2008

Human Microsomal Prostaglandin E Synthase-1 (mPGES-1) Binding with Inhibitors and the Quantitative Structure-Activity Correlation.
J. Chem. Inf. Model., 2008

Dynamic structures of phosphodiesterase-5 active site by combined molecular dynamics simulations and hybrid quantum mechanical/molecular mechanical calculations.
J. Comput. Chem., 2008

Rational design of an enzyme mutant for anti-cocaine therapeutics.
J. Comput. Aided Mol. Des., 2008

2005
First-principle studies of intermolecular and intramolecular catalysis of protonated cocaine.
J. Comput. Chem., 2005

2004
Quantitative Structure-Activity Relationship for Cyclic Imide Derivatives of Protoporphyrinogen Oxidase Inhibitors: A Study of Quantum Chemical Descriptors from Density Functional Theory.
J. Chem. Inf. Model., 2004

2003
Coordination number of zinc ions in the phosphotriesterase active site by molecular dynamics and quantum mechanics.
J. Comput. Chem., 2003


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