Bernard R. Brooks

Orcid: 0000-0002-3586-2730

According to our database1, Bernard R. Brooks authored at least 50 papers between 1994 and 2024.

Collaborative distances:
  • Dijkstra number2 of four.
  • Erdős number3 of four.

Timeline

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Bibliography

2024
MPI-parallelization of the grid inhomogeneous solvation theory calculation.
J. Comput. Chem., April, 2024

2022
Obtaining QM/MM binding free energies in the SAMPL8 drugs of abuse challenge: indirect approaches.
J. Comput. Aided Mol. Des., 2022

GraphVAMPNet, using graph neural networks and variational approach to markov processes for dynamical modeling of biomolecules.
CoRR, 2022

2021
The Extended Eighth-Shell method for periodic boundary conditions with rotational symmetry.
J. Comput. Chem., 2021

A replica exchange umbrella sampling (REUS) approach to predict host-guest binding free energies in SAMPL8 challenge.
J. Comput. Aided Mol. Des., 2021

Variational embedding of protein folding simulations using gaussian mixture variational autoencoders.
CoRR, 2021

2020
A deep learning approach for the blind logP prediction in SAMPL6 challenge.
J. Comput. Aided Mol. Des., 2020

SAMPL6 logP challenge: machine learning and quantum mechanical approaches.
J. Comput. Aided Mol. Des., 2020

Multi-phase Boltzmann weighting: accounting for local inhomogeneity in molecular simulations of water-octanol partition coefficients in the SAMPL6 challenge.
J. Comput. Aided Mol. Des., 2020

Quantum chemical predictions of water-octanol partition coefficients applied to the SAMPL6 logP blind challenge.
J. Comput. Aided Mol. Des., 2020

2018
Absolute and relative pK a predictions via a DFT approach applied to the SAMPL6 blind challenge.
J. Comput. Aided Mol. Des., 2018

An explicit-solvent hybrid QM and MM approach for predicting pKa of small molecules in SAMPL6 challenge.
J. Comput. Aided Mol. Des., 2018

Comparison of the umbrella sampling and the double decoupling method in binding free energy predictions for SAMPL6 octa-acid host-guest challenges.
J. Comput. Aided Mol. Des., 2018

Force matching as a stepping stone to QM/MM CB[8] host/guest binding free energies: a SAMPL6 cautionary tale.
J. Comput. Aided Mol. Des., 2018

Prediction of CB[8] host-guest binding free energies in SAMPL6 using the double-decoupling method.
J. Comput. Aided Mol. Des., 2018

2017
Efficient Strategy for the Calculation of Solvation Free Energies in Water and Chloroform at the Quantum Mechanical/Molecular Mechanical Level.
J. Chem. Inf. Model., October, 2017

OpenMM 7: Rapid development of high performance algorithms for molecular dynamics.
PLoS Comput. Biol., 2017

Absolute binding free energies for octa-acids and guests in SAMPL5 - Evaluating binding free energies for octa-acid and guest complexes in the SAMPL5 blind challenge.
J. Comput. Aided Mol. Des., 2017

Absolute binding free energy calculations of CBClip host-guest systems in the SAMPL5 blind challenge.
J. Comput. Aided Mol. Des., 2017

2016
Self-guided Langevin dynamics via generalized Langevin equation.
J. Comput. Chem., 2016

Blind prediction of distribution in the SAMPL5 challenge with QM based protomer and p<i>K</i> <sub>a</sub> corrections.
J. Comput. Aided Mol. Des., 2016

Calculating distribution coefficients based on multi-scale free energy simulations: an evaluation of MM and QM/MM explicit solvent simulations of water-cyclohexane transfer in the SAMPL5 challenge.
J. Comput. Aided Mol. Des., 2016

Partition coefficients for the SAMPL5 challenge using transfer free energies.
J. Comput. Aided Mol. Des., 2016

Link community detection through global optimization and the inverse resolution limit of partition density.
CoRR, 2016

2015
A Virtual Mixture Approach to the Study of Multistate Equilibrium: Application to Constant pH Simulation in Explicit Water.
PLoS Comput. Biol., 2015

ProBiS-CHARMMing: Web Interface for Prediction and Optimization of Ligands in Protein Binding Sites.
J. Chem. Inf. Model., 2015

Development and implementation of (Q)SAR modeling within the CHARMMing web-user interface.
J. Comput. Chem., 2015

Sigma-RF: prediction of the variability of spatial restraints in template-based modeling by random forest.
BMC Bioinform., 2015

2014
Web-Based Computational Chemistry Education with CHARMMing II: Coarse-Grained Protein Folding.
PLoS Comput. Biol., 2014

Web-Based Computational Chemistry Education with CHARMMing III: Reduction Potentials of Electron Transfer Proteins.
PLoS Comput. Biol., 2014

Web-Based Computational Chemistry Education with CHARMMing I: Lessons and Tutorial.
PLoS Comput. Biol., 2014

Predicting hydration free energies with a hybrid QM/MM approach: an evaluation of implicit and explicit solvation models in SAMPL4.
J. Comput. Aided Mol. Des., 2014

2012
Correlating Protein Hot Spot Surface Analysis Using ProBiS with Simulated Free Energies of Protein-Protein Interfacial Residues.
J. Chem. Inf. Model., 2012

Comparing normal modes across different models and scales: Hessian reduction <i>versus</i> coarse-graining.
J. Comput. Chem., 2012

Simulation of multiphase systems utilizing independent force fields to control intraphase and interphase behavior.
J. Comput. Chem., 2012

Predicting binding affinities of host-guest systems in the SAMPL3 blind challenge: the performance of relative free energy calculations.
J. Comput. Aided Mol. Des., 2012

2011
The distributed diagonal force decomposition method for parallelizing molecular dynamics simulations.
J. Comput. Chem., 2011

2010
Comparative study of various normal mode analysis techniques based on partial Hessians.
J. Comput. Chem., 2010

2009
Artificial reaction coordinate "tunneling" in free-energy calculations: The catalytic reaction of RNase H.
J. Comput. Chem., 2009

CHARMM: The biomolecular simulation program.
J. Comput. Chem., 2009

2008
CHARMMing: A New, Flexible Web Portal for CHARMM.
J. Chem. Inf. Model., 2008

Open Science Grid Study of the Coupling between Conformation and Water Content in the Interior of a Protein.
J. Chem. Inf. Model., 2008

2007
Interfacing Q-Chem and CHARMM to perform QM/MM reaction path calculations.
J. Comput. Chem., 2007

Modeling Of Macromolecular Assemblies with Map Objects.
Proceedings of the International Conference on Bioinformatics & Computational Biology, 2007

2006
Development of small molecules designed to modulate protein-protein interactions.
J. Comput. Aided Mol. Des., 2006

2004
The Local Maximum Clustering Method and Its Application in Microarray Gene Expression Data Analysis.
EURASIP J. Adv. Signal Process., 2004

2003
An improved method for nonbonded list generation: Rapid determination of near-neighbor pairs.
J. Comput. Chem., 2003

1995
Harmonic Analysis of Large Systems. I. Methodology.
J. Comput. Chem., 1995

1994
New Spherical-Cutoff Methods for Long-Range Forces in Macromolecular Simulation.
J. Comput. Chem., 1994

A Truncated Newton Minimizer Adapted for CHARMM and Biomolecular Applications.
J. Comput. Chem., 1994


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