A proof-of-concept pipeline to guide evaluation of tumor tissue perfusion by dynamic contrast-agent imaging: Direct simulation and inverse tracer-kinetic procedures.
Frontiers Bioinform., May, 2023
Quantitative modeling identifies critical cell mechanics driving bile duct lumen formation.
PLoS Comput. Biol., 2022
Guided interactive image segmentation using machine learning and color-based image set clustering.
Bioinform., 2022
Guided interactive image segmentation using machine learning and color based data set clustering.
CoRR, 2020
Quantitative cell-based model predicts mechanical stress response of growing tumor spheroids over various growth conditions and cell lines.
PLoS Comput. Biol., 2019
Automated Quantification of Amyloid Fibrils Morphological Features by Image Processing Techniques.
Proceedings of the 16th IEEE International Symposium on Biomedical Imaging, 2019
Tumor Cell Load and Heterogeneity Estimation From Diffusion-Weighted MRI Calibrated With Histological Data: an Example From Lung Cancer.
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IEEE Trans. Medical Imaging, 2018
Inferring Growth Control Mechanisms in Growing Multi-cellular Spheroids of NSCLC Cells from Spatial-Temporal Image Data.
PLoS Comput. Biol., 2016
TiQuant: software for tissue analysis, quantification and surface reconstruction.
Bioinform., 2015
Modeling Dynamics of Cell-to-Cell Variability in TRAIL-Induced Apoptosis Explains Fractional Killing and Predicts Reversible Resistance.
PLoS Comput. Biol., 2014
Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration.
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Proc. Natl. Acad. Sci. USA, 2010
Individual fates of mesenchymal stem cells in vitro.
BMC Syst. Biol., 2010
A cell-based simulation software for multi-cellular systems.
Bioinform., 2010
Gene network inference from incomplete expression data: transcriptional control of hematopoietic commitment.
Bioinform., 2006
Emergence of Regulatory Networks in Simulated Evolutionary Processes.
Adv. Complex Syst., 2005
Coarse Graining in Simulated Cell Populations.
Adv. Complex Syst., 2005
An individual cell-based model of the growth regulation of epithelial cell-populations in-vitro.
Proceedings of the German Conference on Bioinformatics, 2003
Scaling Laws and Similarity Detection in Sequence Alignment with Gaps.
J. Comput. Biol., 2000
A Statistical Theory of Sequence Alignment with Gaps.
Proceedings of the 6th International Conference on Intelligent Systems for Molecular Biology (ISMB-98), Montréal, Québec, Canada, June 28, 1998