Aleksander S. Popel

According to our database, Aleksander S. Popel authored at least 22 papers between 1990 and 2024.

Collaborative distances:

• Dijkstra number of five.
• Erdős number of four.

2024

From virtual patients to digital twins in immuno-oncology: lessons learned from mechanistic quantitative systems pharmacology modeling.

Hanwen Wang, Theinmozhi Arulraj, Alberto Ippolito, Aleksander S. Popel

npj Digit. Medicine, 2024

Leveraging multi-omics data to empower quantitative systems pharmacology in immuno-oncology.

Theinmozhi Arulraj, Hanwen Wang, Alberto Ippolito, Shuming Zhang, Elana J. Fertig, Aleksander S. Popel

Briefings Bioinform., 2024

2022

Label Cleaning Multiple Instance Learning: Refining Coarse Annotations on Single Whole-Slide Images.

Zhenzhen Wang, Carla Saoud, Sintawat Wangsiricharoen, Aaron W. James, Aleksander S. Popel, Jeremias Sulam

IEEE Trans. Medical Imaging, 2022

Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology model.

Alvaro Ruiz-Martinez, Chang Gong, Hanwen Wang, Richard J. Sové, Haoyang Mi, Holly Kimko, Aleksander S. Popel

PLoS Comput. Biol., 2022

2021

Label Cleaning Multiple Instance Learning: Refining Coarse Annotations on Single Whole-Slide Images.

Zhenzhen Wang, Aleksander S. Popel, Jeremias Sulam

CoRR, 2021

2019

A mechanistic integrative computational model of macrophage polarization: Implications in human pathophysiology.

Chen Zhao, Adam C. Mirando, Richard J. Sové, Thalyta X. Medeiros, Brian H. Annex, Aleksander S. Popel

PLoS Comput. Biol., 2019

2017

Transcriptional and Post-Transcriptional Regulation of Thrombospondin-1 Expression: A Computational Model.

Chen Zhao, Jeffrey S. Isenberg, Aleksander S. Popel

PLoS Comput. Biol., 2017

Computational investigation of sphingosine kinase 1 (SphK1) and calcium dependent ERK1/2 activation downstream of VEGFR2 in endothelial cells.

Hojjat Bazzazi, Aleksander S. Popel

PLoS Comput. Biol., 2017

An agent-based model of triple-negative breast cancer: the interplay between chemokine receptor CCR5 expression, cancer stem cells, and hypoxia.

Kerri-Ann Norton, Travis Wallace, Niranjan B. Pandey, Aleksander S. Popel

BMC Syst. Biol., 2017

2015

Computational Model of MicroRNA Control of HIF-VEGF Pathway: Insights into the Pathophysiology of Ischemic Vascular Disease and Cancer.

Chen Zhao, Aleksander S. Popel

PLoS Comput. Biol., 2015

A 3D Fractal-Based Approach towards Understanding Changes in the Infarcted Heart Microvasculature.

Polyxeni Gkontra, Magdalena M. Zak, Kerri-Ann Norton, Andrés Santos, Aleksander S. Popel, Alicia G. Arroyo

Proceedings of the Medical Image Computing and Computer-Assisted Intervention - MICCAI 2015 - 18th International Conference Munich, Germany, October 5, 2015

2011

Formation of VEGF isoform-specific spatial distributions governing angiogenesis: computational analysis.

Prakash Vempati, Aleksander S. Popel, Feilim Mac Gabhann

BMC Syst. Biol., 2011

Pharmacokinetics and pharmacodynamics of VEGF-neutralizing antibodies.

Stacey D. Finley, Marianne O. Engel-Stefanini, Princess I. Imoukhuede, Aleksander S. Popel

BMC Syst. Biol., 2011

2009

The Presence of VEGF Receptors on the Luminal Surface of Endothelial Cells Affects VEGF Distribution and VEGF Signaling.

Marianne O. Stefanini, Florence T. H. Wu, Feilim Mac Gabhann, Aleksander S. Popel

PLoS Comput. Biol., 2009

Elongation, proliferation & migration differentiate endothelial cell phenotypes and determine capillary sprouting.

Amina A. Qutub, Aleksander S. Popel

BMC Syst. Biol., 2009

Integration of Angiogenesis Modules at Multiple Scales: From Molecular to Tissue.

Amina A. Qutub, Gang Liu, Prakash Vempati, Aleksander S. Popel

Proceedings of the Biocomputing 2009: Proceedings of the Pacific Symposium, 2009

2008

A compartment model of VEGF distribution in blood, healthy and diseased tissues.

Marianne O. Stefanini, Florence T. H. Wu, Feilim Mac Gabhann, Aleksander S. Popel

BMC Syst. Biol., 2008

2006

Targeting Neuropilin-1 to Inhibit VEGF Signaling in Cancer: Comparison of Therapeutic Approaches.

Feilim Mac Gabhann, Aleksander S. Popel

PLoS Comput. Biol., 2006

Computational Model of Vascular Endothelial Growth Factor Spatial Distribution in Muscle and Pro-Angiogenic Cell Therapy.

Feilim Mac Gabhann, James W. Ji, Aleksander S. Popel

PLoS Comput. Biol., 2006

1999

Canine sternal force-displacement relationship during cardiopulmonary resuscitation.

Kreg G. Gruben, Henry R. Halperin, Aleksander S. Popel, Joshua E. Tsitlik

IEEE Trans. Biomed. Eng., 1999

1996

Potential distribution for a spheroidal cell having a conductive membrane in an electric field.

Rocco A. Jerry, Aleksander S. Popel, William E. Brownell

IEEE Trans. Biomed. Eng., 1996

1990

Identification of dynamic mechanical parameters of the human chest during manual cadiopulmonary resuscitation.

Isaac N. Bankman, Kreg G. Gruben, Henry R. Halperin, Aleksander S. Popel, Alan D. Guerci, Joshua E. Tsitlik

IEEE Trans. Biomed. Eng., 1990